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Comprehensive Neurodegenerative Disease Market Forecast 2025-2034: Growth Trends and Strategic Shifts

07-04-2025 08:00 AM CET | Health & Medicine

Press release from: The Business Research Company

Neurodegenerative Disease

Neurodegenerative Disease

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Neurodegenerative Disease Market Size Valuation Forecast: What Will the Market Be Worth by 2025?
In recent times, the neurodegenerative disease market has seen substantial growth. The market, which is projected to ascend from $52.3 billion in 2024 to $57.23 billion in 2025, is projected to increase at a compound annual growth rate (CAGR) of 9.4%. This expansion in past years has been encouraged by the advancement in diagnostic tools, escalated demand for remedies towards symptoms, an increase in clinical studies, growth in public-private associations, and an escalating burden of unaddressed healthcare requirements.

Neurodegenerative Disease Market Size Forecast: What's the Projected Valuation by 2029?
In the coming years, the neurodegenerative disease market is anticipated to experience robust expansion, reaching $81.23 billion in 2029 with a compound annual growth rate (CAGR) of 9.2%. This growth is expected thanks to advancements in gene and cell therapy, the growing use of digital biomarkers, the adoption of precision medicine techniques, an augmented pipeline of disease-modifying drugs, and the increasing application of artificial intelligence in neurology. Key trends to watch for include progress in neuroimaging technology, refined systems for drug delivery to the brain, the creation of customized treatment plans, innovation in biomarker identification, and enhancements in gene editing capabilities.

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What Are the Drivers Transforming the Neurodegenerative Disease Market?
The neurodegenerative disease market is projected to experience significant growth due to an uptick in research and clinical trials. Clinical trials are research studies carried out with human subjects in order to examine the safety and effectiveness of new treatments, drugs or medical equipment. The surge in research and clinical trials can be attributed to the escalating demand for innovative treatments to cater to the changing health needs and enhance the quality of patient care. Clinical trials contribute to neurodegenerative disease research by offering valuable information on the safety and efficacy of new treatments which aids in advancing therapeutic development and improving patient results. For example, in November 2023, the Association of the British Pharmaceutical Industry (ABPI) reported a moderate increase of 4.3% in the number of industry clinical trials commencing annually in the UK, from 394 trials in 2021 to 411 in 2022. Consequently, the surge in research and clinical trials is likely to spur the growth of the neurodegenerative disease market.

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What Long-Term Trends Will Define the Future of the Neurodegenerative Disease Market?
Leading firms in the neurodegenerative disease market are channeling their efforts towards the creation of cutting-edge products like the next-generation adaptive Deep Brain Stimulation (aDBS) systems. The goal behind such development is to elevate the precision of treatment, boost the effects that modify the disease, and improve the patient's quality of life. Next generation adaptive deep brain stimulation (aDBS) systems are sophisticated neuro-modulating devices aimed towards providing real-time, custom treatment for Parkinson's disease. They work by fine-tuning stimulation parameters based on nervous system feedback, maximizing therapeutic results and reducing side effects, ultimately enhancing patient outcomes. For instance, in February 2025, Medtronic - a medical technology firm based in the US, earned the U.S. Food and Drug Administration (USFDA)'s approval for the world's first adaptive deep brain stimulation (aDBS) system devised for Parkinson's disease. This approval relates to the premarket approval (PMA) application for the Percept RC neurostimulator equipped with BrainSense technology. This tech automatically modifies therapy based on the patient's brain signals. It is clinically proven to provide symptom relief for patients suffering from advanced Parkinson's disease and indicates a significant progression in personalized neuromodulation therapies.

Which Segments in the Neurodegenerative Disease Market Offer the Most Profit Potential?
The neurodegenerative disease market covered in this report is segmented -

1) By Disease Type: Parkinson's Disease, Alzheimer's Disease, Multiple Sclerosis, Huntington Disease, Amyotrophic Lateral Sclerosis
2) By Drug Type: N-methyl-D-aspartate Receptor antagonists, Cholinesterase Inhibitors, Dopamine Agonists, Immunomodulatory Drugs, Acetylcholinesterase (AChE) Inhibitors, Antagonist, Monoamine Oxidase B (MAO-B) Inhibitor, Catechol-O-Methyltransferase (COMT) Inhibitor, Selective Serotonin Reuptake Inhibitor (SSRIs), Other Drug Types
3) By Route of Administration: Oral, Injectable, Transdermal, Other Routes Of Administration
4) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies, Other Distribution Channels
5) By End-User: Hospital, Retail, Online

Subsegment:

1) By Parkinson's Disease: Idiopathic Parkinson's Disease, Familial Parkinson's Disease, Early-Onset Parkinson's Disease, Parkinsonism
2) By Alzheimer's Disease: Early-Onset Alzheimer's Disease, Late-Onset Alzheimer's Disease, Familial Alzheimer's Disease (FAD), Inflammatory Subtype, Non-Inflammatory Subtype, Cortical Subtype
3) By Multiple Sclerosis (MS): Clinically Isolated Syndrome (CIS), Relapsing-Remitting MS (RRMS), Secondary Progressive MS (SPMS), Primary Progressive MS (PPMS), Progressive-Relapsing MS (PRMS)
4) By Huntington's Disease: Adult-Onset Huntington's Disease, Juvenile Huntington's Disease
5) By Amyotrophic Lateral Sclerosis (ALS): Classical ALS, Limb-Onset ALS, Bulbar-Onset ALS, Respiratory-Onset ALS, Primary Lateral Sclerosis (PLS), Progressive Muscular Atrophy (PMA), Juvenile ALS, ALS-Parkinsonism-Dementia Complex (ALS-PDC)

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Which Firms Dominate the Neurodegenerative Disease Market by Market Share and Revenue in 2025?
Major companies operating in the neurodegenerative disease market are Pfizer Inc., Johnson & Johnson, F. Hoffmann-La Roche Ltd, AbbVie Inc., Sanofi S.A., Novartis AG, Takeda Pharmaceutical Company Limited, Eli Lilly and Company, Merck & Co. Inc., Biogen Inc., Neurocrine Biosciences Inc., Alnylam Pharmaceuticals Inc., Ionis Pharmaceuticals Inc., Cassava Sciences Inc., Denali Therapeutics Inc., Voyager Therapeutics Inc., AC Immune SA, Amylyx Pharmaceuticals Inc., Sage Therapeutics Inc., Alzheon Inc.

Which Regions Offer the Highest Growth Potential in the Neurodegenerative Disease Market?
North America was the largest region in the neurodegenerative disease market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the neurodegenerative disease market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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