Metabolic Dysfunction-Associated Steatohepatitis Market Growth Driven by Rising Obesity in 2025 | Madrigal Pharmaceuticals, Simson Pharma Limited, Dr. Reddy's Laboratories Ltd., Thermo Fisher Scientific Inc

The Global Metabolic Dysfunction-Associated Steatohepatitis (MASH) Treatment Market reached US$ 1.67 billion in 2023 and is expected to reach US$ 7.64 billion by 2031, growing at a CAGR of 21.8% during the forecast period 2024-2031.

The latest Metabolic Dysfunction-Associated Steatohepatitis market research report from DataM Intelligence delivers a comprehensive analysis of the global Metabolic Dysfunction-Associated Steatohepatitis Market landscape, highlighting emerging trends, market size, competitive dynamics, and key growth drivers. By leveraging advanced analytics, technology trend mapping, and regulatory assessment, the report highlights emerging growth drivers, evolving care models, and investment opportunities. It equips stakeholders with strategic intelligence essential for navigating the complex healthcare ecosystem from clinical innovation to operational efficiency across the forecast period 2025-2033.

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Metabolic Dysfunction-Associated Steatohepatitis (MASH), formerly known as NASH, is a liver disease caused by fat accumulation and inflammation linked to metabolic conditions like obesity and type 2 diabetes. With no approved treatments currently available, the market is witnessing rapid growth driven by a rising global disease burden and intense pharmaceutical R&D activity.

Comprehensive Insight into Metabolic Dysfunction-Associated Steatohepatitis Market Competitor Landscape:

Madrigal Pharmaceuticals, Simson Pharma Limited, Dr. Reddy's Laboratories Ltd., Thermo Fisher Scientific Inc., Biosynth, Affgility Solutions, Conscientia Industrial Co. Ltd., Smolecule Inc., 89 Bio Inc., and Sandoo Pharmaceuticals and Chemicals Co. Ltd. among others

Important Industry Updates:

✅ In June 2024, Eli Lilly announced that they achieved an absence of metabolic dysfunction-associated steatohepatitis without the worsening of fibrosis in more than 50% of patients in a mid-stage study from their Phase II SYNERGY-NASH study. At 52 weeks, 51.8% of patients treated with 5-mg tirzepatide saw an absence of metabolic dysfunction-associated steatohepatitis (MASH) without the worsening of fibrosis. This proportion increased to 62.8% and 73.3% in the 10-mg and 15-mg dose groups, respectively, while only 13.2% of placebo counterparts reached the endpoint.

✅ In May 2024, US-based biopharmaceutical company 89bio began the Phase III ENLIGHTEN-Cirrhosis clinical trial of pegozafermin for treating metabolic dysfunction-associated steatohepatitis (MASH) with compensated cirrhosis.

Metabolic Dysfunction-Associated Steatohepatitis Market Segments Overview:

By Treatment

■ By Drug
■ Rezdiffra

By Therapy

■ Phytic Acid Based Nano-Medicine Therapy
■ Weight Management
■ Diabetes Control
■ Regular Exercise
■ Others

By End-User

■ Hospitals
■ Specialty Clinics
■ Homecare
■ Others

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Methodology and Scope:

This Metabolic Dysfunction-Associated Steatohepatitis Market report is developed using a robust research methodology that combines primary interviews, insights from industry experts, and verified secondary sources such as company filings, trade journals, and trusted databases. It follows a bottom-up and top-down approach to ensure data accuracy through triangulation. The scope of the report covers current market trends, growth potential, and strategic developments across global and regional markets.

Regional Overview for Metabolic Dysfunction-Associated Steatohepatitis Market:

⇥ North America (U.S., Canada, Mexico)
⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)
⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)
⇥ South America (Colombia, Brazil, Argentina, Rest of South America)
⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)

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