Emerging Small Molecule Drug Discovery Market Trends: Small Molecule Drug Discovery Market Thrives On Technological Innovations Shaping the Future of the Industry

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Small Molecule Drug Discovery Market Size Growth Forecast: What to Expect by 2025?
The market size of small molecule drug discovery has seen robust growth in the past few years. The market, which is expected to rise from $62.44 billion in 2024 to $68.57 billion in 2025, will have a compound annual growth rate (CAGR) of 9.8%. The historical period's progression can be attributed to initiatives for drug repurposing, automated processes in drug discovery, amplified r&d investment, regulatory backing for drug development, and advancements in high-throughput screening.

How Will the Small Molecule Drug Discovery Market Size Evolve and Grow by 2029?
The market size of small molecule drug discovery is predicted to experience a significant surge in the upcoming years, reaching $106.91 billion by 2029 with an 11.7% Compound Annual Growth Rate (CAGR). The anticipated expansion throughout the forecast period could be due to the emergence of innovative therapeutic targets, a patient-oriented approach to drug discovery, the advent of drug-device pairing products, real-world evidence application, incorporation of pharmacogenomics, and pressing global health concerns. Among the market trends expected during the forecast are fragment-oriented drug discovery, integrating artificial intelligence into drug discovery, RNA-targeted therapies, strategic collaborations and partnerships, advancement in drug delivery mechanisms, and the use of organoids along with 3D cell culture models.

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What Drivers Are Propelling the Growth of Small Molecule Drug Discovery Market Forward?
An increase in chronic diseases is projected to fuel the expansion of the small molecule drug discovery market. Chronic diseases, which typically endure for a year or longer, interfere with regular activities and require ongoing medical care. Chronic conditions such as HIV, cancer, infections, heart disease, and renal disease can be treated with small-molecule drugs, which are usually more affordable for individuals with chronic illnesses. Consequently, the growing prevalence of chronic diseases is anticipated to stimulate the small molecule drug discovery market. For example, a study by the National Institutes of Health (NIH), a US-based biomedical research institution, forecasted that by 2023, the number of Americans aged 50 and over with at least one chronic disease will increase by 99.5%, from 71.522 million in 2020 to 142.66 million in 2050. Additionally, the population with multimorbidity is expected to rise by 91.16% from 7.8304 million in 2020 to 14.968 million in 2050. Hence, the mounting prevalence of chronic diseases is propelling the small molecule drug discovery market's growth.

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Which Emerging Trends Are Transforming the Small Molecule Drug Discovery Market in 2025?
Cutting-edge technological advancements are becoming a significant trend in the small molecule drug discovery industry. Several leading organizations in this sector are concentrating their efforts on creating innovative products. For instance, in January 2023, Dotmatics, an American company that offers digital science platforms, introduced its Small Molecule Drug Discovery Solution. This novel solution, exclusively developed with an integrated scientific R&D platform featuring pre-set workflows and improved data management features, lessens procedural inefficiencies while accelerating the progression of converting data from valuable insights into strategic decisions.

What Are the Key Segments in the Small Molecule Drug Discovery Market?
The small molecule drug discovery market covered in this report is segmented -

1) By Drug Type: Small Molecule Drugs, Biologic Drugs
2) By Technology: High Throughput Screening, Pharmacogenomics, Combinatorial Chemistry, Nanotechnology, Others
3) By Therapeutic Area: Oncology, Central Nervous System, Cardiovascular, Respiratory, Metabolic Disorders, Gastrointestinal, Others
4) By Process Or Phase: Target ID Or Validation, Hit Generation And Selection, Lead Identification, Lead Optimization
5) By End-User: Pharmaceutical Companies, Contract Research Organizations, Others

Subsegments:
1) By Small Molecule Drugs: Generic Small Molecule Drugs, Novel Small Molecule Drugs
2) By Biologic Drugs: Monoclonal Antibodies, Vaccines, Recombinant Proteins, Cell And Gene Therapies

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Who Are the Key Players Shaping the Small Molecule Drug Discovery Market's Competitive Landscape?
Major companies operating in the small molecule drug discovery market include Pfizer Inc., GlaxoSmithKline plc, AstraZeneca, Boehringer Ingelheim International GmbH, Bristol-Myers Squibb Company, Johnson & Johnson, Gilead Sciences Inc., Merck KGaA, Novartis AG, 4SC AG, Teva Pharmaceutical Industries Ltd., Takeda Pharmaceutical Company Limited, Labcorp Drug Development, ICON Public Limited Company, Charles River Laboratories, Aluda Pharmaceuticals, Clinuvel Pharmaceuticals, Corcept Therapeutics, Edison Oncology, Escend Pharmaceuticals, Terray Therapeutics, Apollomics, Astex Pharmaceuticals, Pardes Biosciences, Xynomic Pharmaceuticals, Zevra Therapeutics, UNION therapeutics, Pharmacosmos, Allarity Therapeutics, Xellia Pharmaceuticals, Cyteir Therapeutics, BigHat Biosciences

What Geographic Markets Are Powering Growth in the Small Molecule Drug Discovery Market?
North America was the largest region in the small molecule drug discovery market in 2024. Europe is expected to be the fastest-growing region in the small molecule drug discovery market report during the forecast period. The regions covered in the small molecule drug discovery market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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