Hashimoto's Thyroiditis market size was ~USD 1,450 million, as per DelveInsight | TNF Pharmaceuticals, and others

Hashimotos Thyroiditis emerging therapies, such as Isomyosamine (MYMD-1), and others, are expected to boost the Hashimotos Thyroiditis Market in the upcoming years.

DelveInsight has launched a new report on "Hashimotos Thyroiditis - Market Insights, Epidemiology, and Market Forecast-2034" that delivers an in-depth understanding of the Hashimotos Thyroiditis, historical and forecasted epidemiology as well as the Hashimotos Thyroiditis market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

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Some of the key facts of the Hashimotos Thyroiditis Market Report:

The total market size of Hashimotos Thyroiditis in the 7MM is approximately USD 589 million in 2023 and is projected to increase during the forecast period (2024-2034).
On June 22, 2025, Dr. Westin Childs summarized the current treatment landscape in "New Treatments for Hashimoto's 2025," emphasizing the unmet need for therapies that preserve thyroid structure and improve patient well‐being beyond just supplementing hormones
On April 9, 2025, DVC Stem posted an overview of innovative approaches-ranging from immunomodulators to stem cell therapy-targeting the autoimmune root of Hashimoto's, moving beyond standard hormone replacement
DelveInsight estimates that in 2024, there were around 20 million diagnosed prevalent cases of Hashimoto's thyroiditis across the 7MM (the U.S., EU4, the UK, and Japan). The U.S. accounted for roughly 55% of these cases, while the EU4 and the UK made up nearly 35%, and Japan represented about 10%.
The US Hashimoto's thyroiditis market size was around USD 1,450 million, accounting for 67% of the total market of 7MM.
The market for Hashimoto's thyroiditis is expected to grow steadily over the forecast period (2025-2034), with a projected compound annual growth rate (CAGR) of 2.6%. In 2024, the market was valued at approximately USD 2.2 billion in the 7MM.
Currently, there is no approved treatment specifically for Hashimoto's thyroiditis. Levothyroxine (LT4) remains the standard therapy, while liothyronine (T3) is sometimes used for persistent symptoms. Desiccated thyroid extract, containing both T4 and T3, is less frequently used due to inconsistencies in composition. Some patients respond better to combination therapy involving both T4 and T3.
DelveInsight estimates that in 2024, there were approximately 49 million prevalent cases of Hashimoto's thyroiditis across the 7MM. The EU4 and the UK collectively reported around 7 million diagnosed cases, representing about 35% of the total.
The United States had the highest number of diagnosed prevalent cases, with roughly 11 million in 2024, and this figure is projected to grow at a compound annual growth rate (CAGR) of 2% between 2025 and 2034.
The current reliance on LT4 and absence of approved therapies underscore the urgent need for innovative treatment options that more effectively address symptoms and improve quality of life for patients with this autoimmune thyroid condition.
Key Hashimotos Thyroiditis companies such as TNF Pharmaceuticals, and others are evaluating new drugs for Hashimotos Thyroiditis to improve the treatment landscape.
Promising Hashimotos Thyroiditis therapies include Isomyosamine (MYMD-1), and others.

Hashimotos Thyroiditis Overview

Hashimoto's thyroiditis, also referred to as chronic lymphocytic or autoimmune thyroiditis, is an autoimmune condition marked by an enlarged thyroid gland, infiltration of lymphocytes, and the presence of autoantibodies against thyroid-specific antigens. It is the leading cause of hypothyroidism and is linked to a higher risk of cardiovascular conditions and certain cancers. The disease can present in several forms, including classic, fibrous, IgG4-related, juvenile, and a transient hyperthyroid phase known as Hashitoxicosis. Secondary triggers may include immune-modulating treatments and environmental factors like excessive iodine intake and vitamin D deficiency. A strong genetic component-particularly involving HLA, CTLA-4, and PTPN22 genes-interacts with epigenetic mechanisms such as DNA methylation and microRNA activity, contributing to disease development. Clinical symptoms range from local effects of thyroid enlargement to systemic signs of hypothyroidism, including fatigue, weight gain, and cognitive difficulties.

Hashimotos Thyroiditis Market Outlook

The management of Hashimoto's thyroiditis varies based on disease severity, thyroid function, and symptom progression. Levothyroxine (LT4) remains the standard treatment, helping to restore hormonal balance and prevent hypothyroidism. For patients who continue to experience symptoms despite normal thyroid-stimulating hormone (TSH) levels, combination therapy using LT4 and liothyronine (T3) may be considered. Desiccated thyroid extract, which contains both T4 and T3, is used less frequently due to inconsistent hormone levels. LT4 primarily addresses hypothyroid symptoms, improving metabolism, energy, and overall health, with better outcomes when started early. However, a subset of patients may continue to experience symptoms, and research suggests combination therapy could help optimize hormone availability in these cases, though it requires close monitoring to avoid side effects.

Newer treatment approaches are focusing on immunomodulatory therapies that target the autoimmune mechanisms responsible for thyroid damage. Early detection and treatment are essential to prevent disease progression. Combining hormone replacement with emerging immunotherapies represents a promising direction for improving long-term outcomes.

Despite current treatment options, there remains a clear need for more effective therapies, as many patients experience ongoing symptoms. Innovative drug development is essential to address these gaps, with only a few candidates-such as Isomyosamine (MYMD-1)-currently showing promise in the pipeline.

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Hashimoto's Thyroiditis Emerging Drugs
Isomyosamine (MYMD-1): TNF Pharmaceuticals

Scope of the Hashimotos Thyroiditis Market Report
Study Period: 2020-2034
Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]
Key Hashimotos Thyroiditis Companies: TNF Pharmaceuticals, and others
Key Hashimotos Thyroiditis Therapies: Isomyosamine (MYMD-1), and others
Hashimotos Thyroiditis Therapeutic Assessment: Hashimotos Thyroiditis current marketed and Hashimotos Thyroiditis emerging therapies
Hashimotos Thyroiditis Market Dynamics: Hashimotos Thyroiditis market drivers and Hashimotos Thyroiditis market barriers
Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
Hashimotos Thyroiditis Unmet Needs, KOL's views, Analyst's views, Hashimotos Thyroiditis Market Access and Reimbursement

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Key benefits of the Hashimotos Thyroiditis Market Report:
Hashimotos Thyroiditis market report covers a descriptive overview and comprehensive insight of the Hashimotos Thyroiditis Epidemiology and Hashimotos Thyroiditis market in the 7MM (the United States, EU5 (Germany, Spain, France, Italy, UK) & Japan).
The Hashimotos Thyroiditis market report provides insights into the current and emerging therapies.
The Hashimotos Thyroiditis market report provides a global historical and forecasted market covering drug outreach in 7MM.
The Hashimotos Thyroiditis market report offers an edge that will help in developing business strategies by understanding trends shaping and driving the Hashimotos Thyroiditis market.

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Table of Contents

1. Report Introduction
2. Executive Summary
3. SWOT analysis
4. Hashimotos Thyroiditis Patient Share (%) Overview at a Glance
5. Hashimotos Thyroiditis Market Overview at a Glance
6. Hashimotos Thyroiditis Disease Background and Overview
7. Hashimotos Thyroiditis Epidemiology and Patient Population
8. Country-Specific Patient Population of Hashimotos Thyroiditis
9. Hashimotos Thyroiditis Current Treatment and Medical Practices
10. Unmet Needs
11. Hashimotos Thyroiditis Emerging Therapies
12. Hashimotos Thyroiditis Market Outlook
13. Country-Wise Hashimotos Thyroiditis Market Analysis (2020-2034)
14. Market Access and Reimbursement of Therapies
15. Market drivers
16. Market barriers
17. Appendix
18. Hashimotos Thyroiditis Report Methodology
19. DelveInsight Capabilities
20. Disclaimer
21. About DelveInsight

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Related Reports:

Hashimotos Thyroiditis Pipeline Insights, DelveInsight

"Hashimotos Thyroiditis Pipeline Insight, 2024" report by DelveInsight outlines comprehensive insights of present clinical development scenarios and growth prospects across the Hashimotos Thyroiditis market. A detailed picture of the Hashimotos Thyroiditis pipeline landscape is provided, which includes the disease overview and Hashimotos Thyroiditis treatment guidelines.

Contact Info:

Kritika Rehani, Assistant Manager, Marketing & Branding
krehani@delveinsight.com
info@delveinsight.com
www.delveinsight.com
+14699457679

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance.

This release was published on openPR.