Chronic Lower Back Pain Market Expected to rise, 2034 | Eli Lilly and Company, Collegium Pharmaceutical, Purdue Pharma LP, BioDelivery Sciences International, Camurus, Braeburn Inc., Scilex Holding, Mesoblast Limited, AnGes MG, Inc., Kolon Life Science, E

The Chronic Lower Back Pain market growth is driven by factors like increase in the prevalence of Chronic Lower Back Pain, investments in research and development, entry of emerging therapies during the study period 2020-2034.

The Chronic Lower Back Pain market report also offers comprehensive insights into the Chronic Lower Back Pain market size, share, Chronic Lower Back Pain epidemiology, emerging therapies, market drivers and barriers, ongoing clinical trials, key collaboration in the space, market uptake by key therapies and companies actively pushing Chronic Lower Back Pain market size growth forward.

Some of the key highlights from the Chronic Lower Back Pain Market Insights Report:

Several key pharmaceutical companies, including Eli Lilly and Company, Collegium Pharmaceutical, Purdue Pharma LP, BioDelivery Sciences International, Camurus, Braeburn Inc., Scilex Holding, Mesoblast Limited, AnGes MG, Inc., Kolon Life Science, Eliem Therapeutics, Allodynic Therapeutics, Sollis Therapeutics, Medtronic Spinal and Biologics, Frontier Biotechnologies, DiscGenics Inc., Pfizer, Persica Pharmaceuticals, BioRestorative Therapies, Vertanical GmbH, Stayble Therapeutics, SpineThera, and others, are developing novel products to improve the Chronic Lower Back Pain treatment outlook.
In January 2025, Pacira BioSciences, Inc. secured FDA clearance for its Smart Tip, designed to target medial branch nerves for chronic low back pain management. The ioverao system provides a drug-free approach, utilizing cryoneurolysis to deliver cold therapy, temporarily disrupting pain signals.
Chronic Lower Back Pain (CLBP) lasts 12+ weeks, even after the initial cause resolves. It's a common issue affecting millions.
In 2023, the U.S. led the 7MM CLBP market at ~$4.2B, projected to grow at a 4% CAGR. Opioids like Xtampza ER & BELBUCA dominated treatment, making up ~$2.96B of the market.
Despite ~68M diagnosed cases, no CLBP-specific approved therapies exist. The market is driven by aging, sedentary lifestyles & new treatments.
Scilex's SP-102 (SEMDEXA), a non-opioid injection for sciatica, may reshape the CLBP landscape upon its expected 2025 U.S. launch.
As per DelveInsight analysis, the Chronic Lower Back Pain market is anticipated to witness growth at a considerable CAGR

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Chronic Lower Back Pain Overview

Chronic low back pain (CLBP) lasts 12+ weeks, even after the initial injury or cause has healed. It's a widespread condition that most people experience at some point. The exact cause remains unclear, but when back pain persists for over three months, it's classified as CLBP. As the second leading cause of disability worldwide, CLBP poses a major economic and social challenge. Its prevalence has surged in recent years, especially among aging populations. Beyond physical discomfort, CLBP has psychological impacts and contributes to lost productivity, high treatment costs, and disability-related expenses. #Healthcare #CLBP

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Chronic Lower Back Pain Epidemiology Insights

In 2023, the U.S. had approximately 31 million diagnosed cases of CLBP, making up about 45% of the 7MM population. The EU4 and the UK together accounted for 40%, while Japan contributed 15%. Among the EU4, Spain had the highest CLBP prevalence (8.6M cases), followed by Germany (6.3M), while France reported the lowest (5M).

Chronic Lower Back Pain Epidemiology Segmentation

DelveInsight's Chronic Lower Back Pain market report is prepared on the basis of epidemiology model. It offers comprehensive insights to the Chronic Lower Back Pain historical patient pools and forecasted Chronic Lower Back Pain patients. The report provides in-depth data of various subtypes and for the same epidemiology is segmented further. The Chronic Lower Back Pain Market report proffers epidemiological analysis for the study period 2020-34 in the 7MM segmented into:

Chronic Lower Back Pain Prevalence
Age-Specific Chronic Lower Back Pain Prevalence
Gender-Specific Chronic Lower Back Pain Prevalence
Diagnosed and Treatable Cases of Chronic Lower Back Pain

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Chronic Lower Back Pain Market Outlook

Chronic low back pain (CLBP) is a complex condition, much like how each patient experiences a unique disease progression. Consequently, treatment plans are highly individualized. Various classes of medications, each with a distinct mechanism of action, allow healthcare providers to target specific aspects of a patient's pain. Additionally, patient-specific factors are carefully considered when designing a treatment regimen to enhance adherence and improve outcomes.

The majority (80-90%) of low back pain cases originate from mechanical causes, such as degenerative disc or joint disease, vertebral fractures, or structural deformities. Less commonly, neurogenic, inflammatory, and other etiologies contribute to the condition. Initial pharmacologic treatment should be based on the underlying cause; however, as pain becomes chronic, a broader, multimodal approach is often required due to the diminishing effectiveness of targeted therapies.

For inflammatory-related low back pain, treatment typically involves anti-inflammatory medications. This includes the early use of nonsteroidal anti-inflammatory drugs (NSAIDs) and, in cases of conditions like rheumatoid arthritis or ankylosing spondylitis, corticosteroids or disease-modifying antirheumatic drugs (DMARDs).

To effectively manage severe pain and improve patient quality of life, certain medications have received FDA approval for long-term, around-the-clock opioid treatment when alternative therapies are insufficient. These include Xtampza (Collegium Pharmaceutical) and BELBUCA (buprenorphine HCL buccal film; BioDelivery Sciences International).
Chronic Lower Back Pain Marketed Drugs
XTAMPZA ER (oxycodone): Collegium Pharmaceutical
Chronic Lower Back Pain Emerging Drugs
Rexlemestrocel-L (MPC-06-ID): Mesoblast Limited/Grünenthal
Semdexa (SP-102): Scilex Holding Company
Chronic Lower Back Pain Key Companies
Eli Lilly and Company, Collegium Pharmaceutical, Purdue Pharma LP, BioDelivery Sciences International, Camurus, Braeburn Inc., Scilex Holding, Mesoblast Limited, AnGes MG, Inc., Kolon Life Science, Eliem Therapeutics, Allodynic Therapeutics, Sollis Therapeutics, Medtronic Spinal and Biologics, Frontier Biotechnologies, DiscGenics Inc., Pfizer, Persica Pharmaceuticals, BioRestorative Therapies, Vertanical GmbH, Stayble Therapeutics, SpineThera, and others
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Scope of the Chronic Lower Back Pain Market Report:

11 Years Forecast
7MM Coverage
Descriptive overview of Chronic Lower Back Pain, causes, signs and symptoms, diagnosis, treatment
Comprehensive insight into Chronic Lower Back Pain epidemiology in the 7MM
Chronic Lower Back Pain marketed and emerging therapies
Chronic Lower Back Pain companies
Chronic Lower Back Pain market drivers and barriers

Table of Contents:

1 Chronic Lower Back Pain Market Key Comprehensive Insights
2 Chronic Lower Back Pain Market Report Introduction
3 Competitive Intelligence Analysis for Chronic Lower Back Pain
4 Chronic Lower Back Pain Market Analysis Overview at a Glance
5 Executive Summary of Chronic Lower Back Pain
6 Chronic Lower Back Pain Epidemiology and Market Methodology
7 Chronic Lower Back Pain Epidemiology and Patient Population
8 Chronic Lower Back Pain Patient Journey
9 Chronic Lower Back Pain Treatment Algorithm, Chronic Lower Back Pain Current Treatment, and Medical Practices
10 Key Endpoints in Chronic Lower Back Pain Clinical Trials
11 Chronic Lower Back Pain Marketed Therapies
12 Chronic Lower Back Pain Emerging Therapies
13 Chronic Lower Back Pain: 7 Major Market Analysis
14 Attribute analysis
15 Access and Reimbursement Overview of Chronic Lower Back Pain
16 Chronic Lower Back Pain Market Key Opinion Leaders Reviews
18 Chronic Lower Back Pain Market Drivers
19 Chronic Lower Back Pain Market Barriers
20 SWOT Analysis
21 Disclaimer
22 DelveInsight Capabilities
23 About DelveInsight

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Related Reports:

Chronic Lower Back Pain Epidemiology 2034

DelveInsight's "Chronic Lower Back Pain - Epidemiology Forecast to 2034" report delivers an in-depth understanding of the disease, historical and forecasted Chronic Lower Back Pain epidemiology in the 7MM, i.e., the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan.

Chronic Lower Back Pain Pipeline 2024

"Chronic Lower Back Pain Pipeline Insights, 2024" report by DelveInsight outlines comprehensive insights of present clinical development scenarios and growth prospects across the Chronic Lower Back Pain market. A detailed picture of the Chronic Lower Back Pain pipeline landscape is provided, which includes the disease overview and Chronic Lower Back Pain treatment guidelines.

Contact Info:
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About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance.

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