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Diabetes-specific Oral Nutritional Supplements Market Size, Clinical Trials, Product Pipelines and Investment Trends, till 2032

06-19-2025 12:02 PM CET | Health & Medicine

Press release from: Datavagyanik Business Intelligence

Diabetes-specific Oral Nutritional Supplements Market Size,

Diabetes-specific Oral Nutritional Supplements Market Size is estimated to be $2550 million in 2024 and is expected to grow at an average yearly rate of around 7% during the timeframe (2025-2032).

What is Diabetes-specific Oral Nutritional Supplements and what are the growth drivers of Diabetes-specific Oral Nutritional Supplements Market?

Diabetes-specific oral nutritional supplements (ONS) are specially formulated dietary products designed to support the nutritional needs of individuals with diabetes or impaired glucose tolerance. These supplements aim to manage blood glucose levels while providing essential nutrients such as proteins, vitamins, minerals, and fiber. Unlike standard oral supplements, diabetes-specific ONS have a controlled glycemic index, lower sugar content, and a balanced composition of macronutrients to help prevent blood sugar spikes. They are used as meal replacements or snacks and are beneficial for people with diabetes who have difficulty maintaining a balanced diet due to age, illness, or poor appetite. These supplements are particularly helpful for patients at risk of malnutrition, those undergoing medical treatments, or elderly individuals with diabetes.

Key Growth Drivers of the Diabetes-specific Oral Nutritional Supplements Market

Rising Prevalence of Diabetes

One of the primary drivers of this market is the growing global prevalence of diabetes. As the number of individuals diagnosed with type 1 and type 2 diabetes continues to rise, there is an increasing demand for specialized nutritional support. Factors such as sedentary lifestyles, unhealthy diets, and rising obesity rates contribute to the surge in diabetes cases, thereby expanding the potential consumer base for diabetes-specific ONS.

Growing Geriatric Population

The aging population worldwide is another significant factor boosting market growth. Older adults are more likely to develop diabetes and often face challenges such as poor appetite, nutrient deficiencies, or difficulty preparing meals. Diabetes-specific ONS offer a convenient and nutritionally adequate solution to support their health and glycemic control, making them a preferred choice in elderly care.

Increased Awareness of Nutritional Management in Diabetes

There is a growing understanding among healthcare professionals and patients about the role of nutrition in diabetes management. With increasing education and awareness campaigns, more people are adopting these supplements as part of their dietary routine to maintain better glucose control. Physicians and dietitians often recommend these products as part of a comprehensive diabetes care plan, further encouraging their adoption.

Advancements in Product Formulation

Manufacturers are continuously innovating to develop better-tasting, more effective, and targeted nutritional supplements for diabetic patients. These advancements include improved taste, texture, and formulations with slow-digesting carbohydrates and higher fiber content. Such innovations not only enhance consumer compliance but also expand the appeal of these products among a broader audience.

Increasing Healthcare Expenditure and Accessibility

As healthcare systems worldwide focus more on preventive care and chronic disease management, diabetes-specific nutritional supplements are being integrated into patient care strategies. Government support, insurance coverage, and the inclusion of these supplements in hospital nutrition programs are further contributing to market expansion. The growing availability of these products through pharmacies, online platforms, and supermarkets is also making them more accessible to the general public.

Rising Incidence of Malnutrition in Diabetic Patients

Many diabetic patients, especially those with coexisting conditions or complications, face a higher risk of malnutrition. This has driven the demand for targeted nutritional solutions that support overall health without negatively impacting glucose levels. The dual need to manage both diabetes and nutritional deficits makes diabetes-specific ONS a crucial part of patient care.



The research and analytics firm Datavagyanik released the updated version of its report on "Diabetes-specific Oral Nutritional Supplements Market - Detailed Analysis, Business Opportunities and Forecasts".

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Clinical Trials in Diabetes-specific Oral Nutritional Supplements Market and New Product Pipelines

Clinical research into diabetes‐specific oral nutritional supplements (ONS) is focused on examining their impact on glycemic control, nutritional status, and patient quality of life. Trials often compare these tailored supplements with standard nutritional beverages or placebo controls, investigating outcomes such as blood glucose levels (HbA1c, fasting glucose), insulin sensitivity, lipid profiles, and body composition. Researchers also explore markers of inflammation and oxidative stress, as well as patient‐reported measures like satiety and dietary adherence when using ONS as meal replacements or snacks.

Key Clinical Trial Findings

Several randomized controlled trials have revealed promising results. Studies show that diabetes‐specific ONS can support modest improvements in HbA1c and fasting glucose when used as part of a meal plan. Reduction in post‐prandial glucose spikes has been observed, attributed to the low glycemic index and higher fiber or protein content. Additionally, trials indicate that these supplements help maintain or improve lean body mass in older adults with diabetes, reducing the risk of muscle wasting or malnutrition. Improved satiety and patient acceptability have been reported, suggesting favorable compliance when these ONS are used over a sustained period.

Target Populations and Study Designs

Clinical trials often focus on high‐risk groups such as elderly individuals, hospitalized patients, or those with complications like diabetic nephropathy or foot ulcers. Parallel‐group designs and crossover studies are common, with intervention durations ranging from four weeks to six months. Nutritional status is frequently assessed using measures such as body mass index, serum albumin, and prealbumin. Some studies include economic evaluations, exploring the potential cost savings through reduced hospitalizations or complications by improving overall nutritional and glycemic status.

Ongoing and Recently Completed Trials

Recent and ongoing trials are increasingly targeting specific subpopulations, including those with type 1 diabetes, gestational diabetes, or pre‐diabetes. Innovative protocols explore using diabetes‐specific ONS in hospital or long‐term care settings, assessing both metabolic outcomes and clinical endpoints like infection rates or wound healing. Emerging research examines the impact on gut microbiota and inflammatory biomarkers, offering insights into the broader physiological effects of sustained use.

New Product Pipelines

The pipeline for diabetes‐specific ONS is becoming more sophisticated, with manufacturers developing products tailored to specific patient needs. These include high‐fiber formulations designed to slow carbohydrate absorption, high‐protein blends to support muscle mass, and low‐lactose or plant‐based alternatives for those with dietary restrictions. Flavor variety and texture improvements are a priority to address taste fatigue and increase long‐term user acceptance.

Functional Fortification and Micronutrient Innovation

New pipelines feature fortification with functional ingredients such as omega‐3 fatty acids, specific amino acids (like leucine), and antioxidants. These additions aim to offer metabolic benefits beyond basic nutrition-supporting cardiovascular health, insulin sensitivity, and inflammation control. Micronutrient enhancement, including vitamin D, magnesium, and zinc, is also a growing focus, targeting gaps commonly observed in diabetic populations.

Digital Integration and Personalized Nutrition

A notable innovation trend involves integration with digital health. Some manufacturers are piloting apps that sync with blood glucose monitors or wearable devices to create personalized usage recommendations. Data analytics enable tailored dosing, flavor preferences, and timing for optimal metabolic outcomes. This convergence of nutrition and digital monitoring holds potential to enhance patient engagement and measure real‐world effectiveness.



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Important target segments driving the demand for Diabetes-specific Oral Nutritional Supplements Market

One of the most critical target segments for diabetes-specific oral nutritional supplements (ONS) is the aging population. Older adults often face challenges such as poor appetite, difficulty chewing, or difficulty preparing balanced meals. Many are also living with type 2 diabetes or impaired glucose tolerance. This segment requires easy-to-consume, nutrient-rich solutions that help maintain glycemic control while preventing malnutrition and muscle wasting. Diabetes-specific ONS are well-suited for this demographic, especially in long-term care facilities and home healthcare settings.

Hospitalized and Post-operative Patients

Patients with diabetes who are hospitalized or recovering from surgery often have increased nutritional needs. They may be at risk of malnutrition due to acute illness, reduced food intake, or specific medical conditions such as infections, diabetic foot ulcers, or kidney disease. These patients benefit from targeted nutrition that stabilizes blood sugar levels while accelerating recovery. Hospitals and rehabilitation centers are increasingly incorporating diabetes-specific ONS into patient care protocols, making this a strong growth segment.

Patients with Chronic Diabetes Complications

Individuals living with diabetes-related complications-such as neuropathy, nephropathy, or cardiovascular disease-form another key segment. These patients often have additional dietary restrictions and need specialized nutrition that supports overall health without spiking blood sugar. Diabetes-specific ONS formulated with low glycemic carbohydrates and enhanced with vitamins, minerals, and anti-inflammatory components are highly beneficial for these patients and are frequently recommended by healthcare providers.

Overweight and Obese Diabetic Individuals

People with diabetes who are also overweight or obese require careful dietary planning to manage both glucose levels and weight. Diabetes-specific ONS are being increasingly used as meal replacements or supplements in structured weight-loss programs tailored for diabetic individuals. These products help in reducing calorie intake while providing adequate nutrients, making them valuable tools for diabetes management and weight control.

Active Working-age Adults with Type 2 Diabetes

Busy professionals or working-age adults with diabetes often struggle to maintain a healthy diet due to time constraints. This segment prefers convenient, ready-to-consume nutritional options that fit into their daily routines. Diabetes-specific ONS offer a quick and balanced solution that helps maintain energy levels, supports glucose control, and fills nutritional gaps, especially when meals are skipped or rushed.

Health-conscious Individuals at Risk of Diabetes

Pre-diabetic individuals or those with a family history of diabetes are increasingly adopting preventive strategies through diet and lifestyle. This segment is turning to diabetes-specific ONS as part of a proactive approach to manage blood sugar and overall health. These users are often motivated by health awareness campaigns and recommendations from nutritionists or primary care physicians.

Sports and Fitness Enthusiasts with Diabetes

Although smaller in size, the fitness-conscious diabetic segment is emerging as a notable contributor to demand. Active individuals with diabetes need energy support and muscle recovery nutrition that also respects blood sugar control. Specialized ONS with higher protein, controlled carbs, and added electrolytes appeal to this niche but growing group.

Key Players in Diabetes-specific Oral Nutritional Supplements, Market Share

The diabetes-specific oral nutritional supplements market is highly competitive and moderately consolidated, with a few global players holding significant market shares. These companies have established strong brand portfolios, advanced research and development capabilities, and extensive distribution networks. Their products are widely used in hospitals, pharmacies, and retail outlets, catering to various patient segments across the globe. In addition to multinational corporations, several regional and emerging companies are contributing to the market's growth, particularly in developing economies.

Abbott Laboratories

Abbott is one of the leading players in the diabetes-specific oral nutritional supplements market. With a robust product line focused on diabetes management, the company has a strong presence in both developed and emerging markets. Abbott's products are widely recommended by healthcare professionals and are part of clinical nutrition programs in hospitals and outpatient care. Its long-standing credibility and continuous innovation in formula development have helped the company maintain a dominant position.

Nestlé Health Science

Nestlé Health Science is another major player with a broad range of nutritional products specifically designed for people with diabetes. Through its targeted offerings and strategic investments in medical nutrition, the company has expanded its footprint in both clinical and retail markets. Nestlé's ability to adapt its products to regional dietary preferences and its strong marketing strategies have reinforced its market presence, especially in Europe and Asia.

Danone Nutricia

Danone Nutricia plays a crucial role in the diabetes-specific ONS segment, particularly in the European market. The company focuses on clinically tested nutritional solutions aimed at managing chronic diseases like diabetes. Its products are often used in long-term care facilities and by elderly diabetic patients. Danone's emphasis on evidence-based nutrition and its collaborations with healthcare professionals have made it a trusted name in the industry.

Fresenius Kabi

Fresenius Kabi, known for its expertise in clinical nutrition, has a growing portfolio of diabetes-specific oral nutritional supplements. The company caters primarily to hospitalized patients and those in critical care, making it a preferred choice in institutional settings. With a focus on clinical efficacy and patient outcomes, Fresenius Kabi continues to expand its market share through specialized nutrition products.

Other Notable Players

Other important contributors to the market include companies like Pfizer, Baxter International, and Mead Johnson, which offer niche or complementary diabetes-specific nutrition products. These companies leverage their existing healthcare infrastructure to distribute and promote targeted nutritional supplements.

In addition, regional companies in Asia, Latin America, and the Middle East are developing cost-effective and locally relevant products. These emerging players are gradually gaining traction in price-sensitive markets, contributing to overall market diversification.



Key Questions Answered in the Diabetes-specific Oral Nutritional Supplements market report:

What is the total global Diabetes-specific Oral Nutritional Supplements Sales, and how has it changed over the past five years?

What is Diabetes-specific Oral Nutritional Supplements investment trend?

Which countries have the highest Diabetes-specific Oral Nutritional Supplements, and what factors contribute to their dominance in the market?

How does Diabetes-specific Oral Nutritional Supplements Sales vary across key manufacturers, and what expansions have been observed recently?

What is the current global revenue generated from Diabetes-specific Oral Nutritional Supplements Sales, and how does it compare to previous years?

Which industries drive the highest demand for Diabetes-specific Oral Nutritional Supplements, and how is this demand expected to evolve in the next five years?

What are the major challenges impacting Diabetes-specific Oral Nutritional Supplements industry and supply chain operations across key markets?

How do government policies, environmental regulations, and trade restrictions affect Diabetes-specific Oral Nutritional Supplements and market dynamics?

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