Press release
Cystic Fibrosis Pipeline Appears Robust With 50+ Key Pharma Companies Actively Working in the Therapeutics Segment | DelveInsight
Stay ahead with the latest insights! Download DelveInsight's comprehensive Cystic Fibrosis Pipeline Report to explore emerging therapies, key players, and future treatment landscapes @ Cystic Fibrosis Pipeline Outlook Report [https://www.delveinsight.com/sample-request/cystic-fibrosis-pipeline?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]
Key Takeaways from the Cystic Fibrosis Pipeline Report
* In May 2025, Boehringer Ingelheim announced a study is for people with cystic fibrosis who took part in a previous study with a medicine called BI 3720931. The main purpose of this study is to monitor the long-term health of participants who were treated with BI 3720931 in the previous study. Participants in this study do not receive additional treatment with BI 3720931.
* In May 2025, Vertex Pharmaceuticals Incorporated conducted a study is to evaluate the pharmacokinetics, safety, tolerability and efficacy of VX-121/tezacaftor/deutivacaftor (VX-121/TEZ/D-IVA) in CF participants with at least 1 triple combination responsive (TCR) mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.
* DelveInsight's Cystic Fibrosis pipeline report depicts a robust space with 50+ active players working to develop 55+ pipeline therapies for Cystic Fibrosis treatment.
* The leading Cystic Fibrosis Companies such as Verona Pharma, Armata Pharmaceuticals, 4D Molecular Therapeutics, Spirovant Sciences, Vertex Pharmaceuticals, Krystal Biotech, Porosome Therapeutics, SpliSense, Enterprise Therapeutics Ltd and others.
* Promising Cystic fibrosis Pipeline Therapies such as Tigerase Registered , Pulmozyme Registered , danazol, Brensocatib, SPL84, ETD001, ELX/TEZ/IVA, BI 3720931, JBT-101 (lenabasum) and others.
Discover how the Cystic Fibrosis treatment paradigm is evolving. Access DelveInsight's in-depth Cystic Fibrosis Pipeline Analysis for a closer look at promising breakthroughs @ Cystic Fibrosis Clinical Trials and Studies [https://www.delveinsight.com/sample-request/cystic-fibrosis-pipeline?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]
Cystic Fibrosis Emerging Drugs Profile
* AP-PA02: Armata Pharmaceuticals
AP-PA02 is a therapeutic phage cocktail that targets the pathogen P. aeruginosa, to treat serious respiratory infections, with an emphasis on patients with cystic fibrosis (CF) and non-cystic fibrosis bronchiectasis (NCFB). Phages that comprise AP-PA02 were selected with desired attributes for a product candidate targeting P. aeruginosa lung infections. AP-PA02 is comprised of a cocktail of natural P. aeruginosa phages originating from distinct families and subfamilies, targeting multiple receptor classes, functioning with compatibility and cooperativity, and further characterized by being highly potent and having a broad host range. Currently, the drug is in the Phase II stage of its development for the treatment of Cystic Fibrosis.
* VX-522: Vertex Pharmaceuticals
VX-522 is an investigational messenger ribonucleic acid (mRNA) therapy aims to address the underlying cause of cystic fibrosis (CF). It is being evaluated by Vertex to treat lung disease for people living with CF who cannot benefit from cystic fibrosis transmembrane conductance regulator (CFTR) modulator treatments because they do not make any CFTR protein that responds to a CFTR modulator therapy. VX-522 is delivered to the lung through inhalation of a CFTR mRNA encapsulated by a lipid nanoparticle. Once delivered to the target lung cells, the mRNA is designed to produce functional copies of the CFTR protein. VX-522 is the result of an exclusive research collaboration established with Moderna in 2016. Currently the drug is in Phase I/II stage of its development for the treatment of Cystic fibrosis.
* KB407: Krystal Biotech
KB407 is an investigational, redosable gene therapy designed to correct the underlying cause of CF by delivering two copies of the CFTR gene directly to the airway epithelial cells when delivered via a nebulizer. By inducing expression of full length, normal CFTR protein in the lung, treatment with KB407 has potential to restore ion and water flow into and out of lung cells to correct the lung manifestations of the disease in patients regardless of their underlying genetic mutation. Currently the drug is in Phase I stage of its development for the treatment of Cystic fibrosis.
* SPL23: SpliSense
The CF W1282X mutation generates a Premature Termination Codon (PTC), leading to RNA degradation induced by the Nonsense Mediated RNA Decay (NMD) mechanism. W1282X does not respond to CFTR modulator drugs. Heterozygous patients carrying the F508del mutation and a minimal function mutation are responsive to Vertex triple combination therapy (Trikafta Registered ). Significantly, around 50% of CF patients carrying W1282X also carry a non-F508del mutation on the second allele. For those patients, no effective treatment is available. SPL23 ASO given by inhalation, penetrates the cells and induces skipping over exon 23 in the CFTR transcript. Skipping exon 23 bypasses the NMD leading to mature and active CFTR. The activity of these CFTR channels can be further augmented by CFTR modulators. Currently the drug is in Preclinical stage of its development for the treatment of Cystic fibrosis.
The Cystic Fibrosis Pipeline Report Provides Insights into
* The report provides detailed insights about companies that are developing therapies for the treatment of Cystic Fibrosis with aggregate therapies developed by each company for the same.
* It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Cystic Fibrosis Treatment.
* Cystic Fibrosis Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
* Cystic Fibrosis Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
* Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Cystic Fibrosis market
Explore groundbreaking therapies and clinical trials in the Cystic Fibrosis Pipeline. Access DelveInsight's detailed report now! @ New Cystic Fibrosis Drugs [https://www.delveinsight.com/sample-request/cystic-fibrosis-pipeline?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]
Cystic Fibrosis Companies
Verona Pharma, Armata Pharmaceuticals, 4D Molecular Therapeutics, Spirovant Sciences, Vertex Pharmaceuticals, Krystal Biotech, Porosome Therapeutics, SpliSense, Enterprise Therapeutics Ltd and others.
Cystic fibrosis pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
* Intravenous
* Subcutaneous
* Oral
* Intramuscular
Cystic Fibrosis Products have been categorized under various Molecule types such as
* Monoclonal antibody
* Small molecule
* Peptide
Download DelveInsight's latest report to gain strategic insights into upcoming therapies and key developments @ Cystic Fibrosis Market Drivers and Barriers, and Future Perspectives [https://www.delveinsight.com/sample-request/cystic-fibrosis-pipeline?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]
Scope of the Cystic Fibrosis Pipeline Report
* Coverage- Global
* Cystic Fibrosis Companies- Verona Pharma, Armata Pharmaceuticals, 4D Molecular Therapeutics, Spirovant Sciences, Vertex Pharmaceuticals, Krystal Biotech, Porosome Therapeutics, SpliSense, Enterprise Therapeutics Ltd and others.
* Cystic fibrosis Pipeline Therapies- Tigerase Registered , Pulmozyme Registered , danazol, Brensocatib, SPL84, ETD001, ELX/TEZ/IVA, BI 3720931, JBT-101 (lenabasum) and others.
* Cystic Fibrosis Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
* Cystic Fibrosis Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
Which companies are leading the race in Cystic Fibrosis drug development? Find out in DelveInsight's exclusive Cystic Fibrosis Pipeline Report-access it now! @ Cystic Fibrosis Emerging Drugs and Major Companies [https://www.delveinsight.com/sample-request/cystic-fibrosis-pipeline?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=ypr]
Table of Content
* Introduction
* Executive Summary
* Cystic Fibrosis: Overview
* Pipeline Therapeutics
* Therapeutic Assessment
* Cystic Fibrosis - DelveInsight's Analytical Perspective
* Late Stage Products (Phase III)
* Drug name: Company Name
* Drug profiles in the detailed report.....
* Mid-Stage Products (Phase II)
* AP-PA02: Armata Pharmaceuticals
* Drug profiles in the detailed report.....
* Early Stage Products (Phase I)
* VX-522: Vertex Pharmaceuticals
* Drug profiles in the detailed report.....
* Preclinical and Discovery Stage Products
* SPL23: SpliSense
* Drug profiles in the detailed report.....
* Inactive Products
* Cystic Fibrosis -Key Companies
* Cystic Fibrosis -Key Products
* Cystic Fibrosis - Unmet Needs
* Cystic Fibrosis - Market Drivers and Barriers
* Cystic Fibrosis - Future Perspectives and Conclusion
* Cystic Fibrosis -Analyst Views
* Cystic Fibrosis- Key Companies
* Appendix
About Us
DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve.
Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Yash Bhardwaj
Email:Send Email [https://www.abnewswire.com/email_contact_us.php?pr=cystic-fibrosis-pipeline-appears-robust-with-50-key-pharma-companies-actively-working-in-the-therapeutics-segment-delveinsight]
Phone: 09650213330
Address:304 S. Jones Blvd #2432
City: Las Vegas
State: NV
Country: United States
Website: https://www.delveinsight.com/report-store/cystic-fibrosis-pipeline
Legal Disclaimer: Information contained on this page is provided by an independent third-party content provider. ABNewswire makes no warranties or responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you are affiliated with this article or have any complaints or copyright issues related to this article and would like it to be removed, please contact retract@swscontact.com
This release was published on openPR.
Permanent link to this press release:
Copy
Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.
You can edit or delete your press release Cystic Fibrosis Pipeline Appears Robust With 50+ Key Pharma Companies Actively Working in the Therapeutics Segment | DelveInsight here
News-ID: 4070860 • Views: …
More Releases from ABNewswire
Market Outlook Projects Steady Growth for Luxury Custom Home Builders in 2025
As families invest in properties that reflect their lifestyle and long-term goals, the role of custom home builders in Gulf Shores AL grows increasingly vital.
The demand for luxury custom home builders [https://ddandbllc.com/custom-home-pool-builder-gulf-shores-al/] continues to rise across the United States, with Gulf Shores, AL, emerging as a key market for homeowners seeking elegance, comfort, and modern design. While many search for home builders near me, the region shows strong momentum fueled…
Desman Orthodontics Launches "Smiles for Students" Scholarship Orthodonist Servi …
For many families in the area, finding a trusted local provider is a priority. As an established orthodontist Port St Lucie families have relied on for years, Desman Orthodontics is uniquely positioned to understand the needs of the community. The practice's decision to create this scholarship stems from a recognition that a healthy, confident smile can have a profound impact on a young person's social development and self-esteem, yet it…
Lone Wolf Roofing Strengthens Its Presence in LaPlace As the Top Roofer in LaPla …
Lone Wolf Roofing is the best roofer in LaPlace Louisiana.
Image: https://www.abnewswire.com/upload/2025/09/d18162e78e8b91dcdbe94df43778e8d2.jpg
Lone Wolf Roofing, a premier Louisiana-based roofing company, today announced the expansion of its services in LaPlace, offering homeowners and businesses access to unmatched craftsmanship, a 100-Year Warranty, and an unprecedented promise: if installation does not begin within 24 hours of signing, the roof is free.
With Louisiana communities facing recurring storms, unpredictable weather, and high roofing costs, Lone Wolf Roofing's…
Family-Owned Meigel Home Innovations Expands Operations to Meet Growing Kitchen …
The decision to expand was driven by a consistent increase in project inquiries over the past several years. "We've seen a fundamental shift," explains a company representative for Meigel Home Improvements. "Homeowners are no longer just fixing a leaky faucet or replacing worn-out countertops. They are undertaking comprehensive transformations. They want a kitchen remodel near me that reflects a modern lifestyle-open-concept layouts, smart storage solutions, and energy-efficient appliances.
HAUPPAUGE, NY -…
More Releases for Cystic
Cystic Fibrosis Market Report-Growth with Industry Study, Detailed Analysis | Cy …
The research study contains an in detail descriptive overview and analysis of the Cystic Fibrosis Market, a summary of the market shares constituted by each component, the annual growth of each sector, and the revenue potential of the section. In addition, Cystic Fibrosis Market production and consumption data are used to determine the geographical features.
Get FREE PDF sample of the Report @ https://www.reportsnreports.com/contacts/requestsample.aspx?name=3639856
Top Company Profile Analysis in this Report-
Cystic Fibrosis…
The Cystic Fibrosis Market to Witness Robust Growth Due to Increasing Cases of C …
Cystic fibrosis is a rare, progressive, life-threatening disease results in the formation of thick mucus that builds up in the lungs, digestive tract, and other parts of the body. If left untreated, it leads to severe digestive and respiratory problems as well as other complications such as infections and diabetes. According to the Cystic Fibrosis Foundation, more than 70,000 people are living with cystic fibrosis around the world. As the…
Cystic Fibrosis Market Opportunity Analysis, 2018-2026
Cystic fibrosis (CF) is a genetic disorder that usually affects the lungs and may also affect the pancreas, kidneys, liver, and intestine. Long-term repercussions including difficulty in breathing and coughing as a result of recurrent lung infections can be seen in CF. Some of the other signs and symptoms include sinus infections, poor growth, infertility in males, fatty stool, and guild of the fingers and toes. Different individuals may have…
Cystic Fibrosis Therapeutics Market Research Reports 2017
This report studies sales (consumption) of Cystic Fibrosis Therapeutics in Europe market, especially in Germany, France, UK, Russia, Italy, Spain and Benelux, focuses on top players in these countries, with sales, price, revenue and market share for each player in these Countries, covering
Vertex Pharmaceuticals , F. Hoffmann-La Roche , AbbVie , Gilead Science , Novartis , AstraZeneca , Bayer , Celtaxsys , Pharmaxis , ProQR Therapeutics , PTC Therapeutics…
Cystic Fibrosis - Heat Map and Analysis
ReportsWorldwide has announced the addition of a new report title Cystic Fibrosis - Heat Map and Analysis to its growing collection of premium market research reports.
Cystic fibrosis (CF) is a progressive genetic condition and is the result of a patient inheriting a faulty cystic fibroses transmembrane conductance regulator (CFTR) gene from both parents. The defective CFTR genes produce faulty CFTR proteins on the body’s epithelial cells, and result in…
Cystic Fibrosis - Heat Map And Analysis
MarketResearchReports.Biz is providing you Latest Market Research report of "Cystic Fibrosis - Heat Map And Analysis".
Cystic fibrosis (CF) is a progressive genetic condition and is the result of a patient inheriting a faulty cystic fibroses transmembrane conductance regulator (CFTR) gene from both parents. The defective CFTR genes produce faulty CFTR proteins on the body?s epithelial cells, and result in the buildup of a thick and sticky mucus in the lungs…
