Alport Syndrome Market Forecast 2034: Clinical Trials, EMA, PDMA, FDA Approvals, Medication, Therapies, Revenue, Statistics, Prevalence, and Companies by DelveInsight

(Albany, USA) DelveInsight's "Alport Syndrome Market Insights, Epidemiology, and Market Forecast-2034" report delivers an in-depth understanding of Alport Syndrome, historical and forecasted epidemiology as well as the Alport Syndrome market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom), and Japan.

The Alport Syndrome market report provides current treatment practices, emerging drugs, the market share of the individual therapies, and the current and forecasted Alport Syndrome market size from 2020 to 2034, segmented by seven major markets. The Report also covers current Alport Syndrome treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best opportunities and assesses the underlying potential of the Alport Syndrome market.

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Some facts of the Alport Syndrome Market Report are:
• According to DelveInsight, Alport Syndrome market size is expected to grow at a CAGR of 69% by 2034.
• In 7MM, Alport syndrome market size was estimated to be ~USD 20 million in 2023, which is expected to show positive growth by 2034.
• Leading Alport Syndrome companies working in the market are Eloxx Pharmaceuticals, River 3 Renal Corp, Chinook Therapeutic, Travere Therapeutics, Reata Pharmaceuticals, and others.
• Key Alport Syndrome Therapies expected to launch in the market are ELX-02, Atrasentan, Finerenone, Setanaxib, BAY3401016, and others.
• In April 2025, Travere Therapeutics, Inc announced results of a Phase 2, Open-Label, Single-Arm, Cohort Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Sparsentan Treatment in Pediatric Subjects With Selected Proteinuric Glomerular Diseases
• In April 2025, Enyo Pharma announced results of a Vonafexor Fixed Dose-escalation Safety and Proof-of-concept Study in Patients With at Risk of Progression Alport Syndrome
• On May 2025, Calliditas Therapeutics AB announced results of a Phase 2a, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of the NOX1/4 Inhibitor Setanaxib in Patients With Alport Syndrome.
• On May 2024, Chinook Therapeutics, Inc announced results of a Phase 2, Open-Label, Basket Study of Atrasentan in Patients With Proteinuric Glomerular Diseases.
• In January 2024, ENYO Pharma announced that the U.S. Food and Drug Administration (FDA) has approved its Investigational New Drug (IND) application, allowing the company to begin a Phase 2 clinical study of Vonafexor, a highly selective FXR agonist, for the treatment of Alport Syndrome.
• In 2022, there were around 2,200 cases of Alport syndrome in the age group 2-11, nearly 1,900 cases in the age group 12-17, and almost 25,000 cases in the age group 18 and above across the 7 Major Markets (7MM).
• The Alport Syndrome market is expected to surge due to the disease's increasing prevalence and awareness during the forecast period. Furthermore, launching various multiple-stage Alport Syndrome pipeline products will significantly revolutionize the Alport Syndrome market dynamics.
• The overall number of existing cases of Alport Syndrome across the seven major markets (7MM) was approximately 160,000 in 2023, with projections indicating a rise by 2034.
• In the United States, there were nearly 68,000 existing cases of Alport Syndrome in 2023.
• In 2023, gender-specific cases of Alport Syndrome in the US consisted of approximately 52% males and 48% females.
• In 2023, among the type-specific cases, approximately 11,500 cases were attributed to XLAS, which constituted 85% of the cases in the US.

Alport Syndrome Overview
Alport Syndrome is a genetic disorder affecting the kidneys, ears, and eyes, primarily caused by mutations in genes responsible for producing collagen, a crucial protein in the body's connective tissues. This syndrome primarily manifests as progressive kidney disease, leading to renal failure in severe cases. Symptoms often include hematuria (blood in urine), proteinuria (protein in urine), high blood pressure, and hearing loss, typically starting in childhood or adolescence. Ocular abnormalities like lens dislocation and retinopathy may also occur. Diagnosis involves genetic testing, kidney biopsy, and evaluation of symptoms. Treatment aims to manage symptoms and slow kidney damage progression through medications controlling blood pressure and proteinuria. In advanced stages, kidney transplant or dialysis may be necessary. Regular monitoring and early intervention are vital in managing the condition and preventing complications.

Learn more about Alport Syndrome treatment algorithms in different geographies, and patient journeys. Contact to receive a sample @ https://www.delveinsight.com/sample-request/alport-syndrome-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr

Alport Syndrome Market
The Alport Syndrome market outlook of the report helps to build a detailed comprehension of the historical, current, and forecasted Alport Syndrome market trends by analyzing the impact of current Alport Syndrome therapies on the market and unmet needs, and drivers, barriers, and demand for better technology.

This segment gives a thorough detail of the Alport Syndrome market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated Alport Syndrome market data are presented with relevant tables and graphs to give a clear view of the market at first sight.

The Alport Syndrome market is primarily driven by increasing awareness, earlier diagnosis due to advancements in genetic testing, and a growing pipeline of promising therapies targeting the underlying molecular mechanisms of the disease. Supportive regulatory initiatives, such as orphan drug designations and incentives for rare disease research, further encourage innovation and investment in Alport Syndrome treatment development. Additionally, heightened patient advocacy efforts and expanding clinical trial networks are accelerating research progress.

However, the market faces significant barriers, including the rarity of the disease, which makes patient recruitment for clinical trials challenging, and the high cost associated with genetic testing and novel therapies. Limited therapeutic options that can slow disease progression without offering a definitive cure also restrict broader adoption. Moreover, a lack of widespread physician familiarity with Alport Syndrome can delay diagnosis and appropriate treatment, impacting patient outcomes and market growth.

According to DelveInsight, the Alport Syndrome market in 7MM is expected to witness a major change in the study period 2020-2034.

Alport Syndrome Epidemiology
The Alport Syndrome epidemiology section provides insights into the historical and current Alport Syndrome patient pool and forecasted trends for seven individual major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the Alport Syndrome market report also provides the diagnosed patient pool, trends, and assumptions.

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Alport Syndrome Drugs Uptake
This section focuses on the uptake rate of the potential Alport Syndrome drugs recently launched in the Alport Syndrome market or expected to be launched in 2020-2034. The analysis covers the Alport Syndrome market uptake by drugs, patient uptake by therapies, and sales of each drug.
Alport Syndrome Drugs Uptake helps in understanding the drugs with the most rapid uptake and the reasons behind the maximal use of new drugs and allows the comparison of the drugs based on Alport Syndrome market share and size, which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

Alport Syndrome Pipeline Development Activities
The Alport Syndrome report provides insights into different therapeutic candidates in Phase II, and Phase III stages. It also analyses Alport Syndrome key players involved in developing targeted therapeutics.

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Alport Syndrome Therapeutics Assessment
Major key companies are working proactively in the Alport Syndrome Therapeutics market to develop novel therapies which will drive the Alport Syndrome treatment markets in the upcoming years are Eloxx Pharmaceuticals (NASDAQ: ELOX), River 3 Renal Corp (NASDAQ: RRRN), Chinook Therapeutics (NASDAQ: KDNY), Travere Therapeutics (NASDAQ: TVTX), Reata Pharmaceuticals (NASDAQ: RETA), and others.

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Alport Syndrome Report Key Insights
1. Alport Syndrome Patient Population
2. Alport Syndrome Market Size and Trends
3. Key Cross Competition in the Alport Syndrome Market
4. Alport Syndrome Market Dynamics (Key Drivers and Barriers)
5. Alport Syndrome Market Opportunities
6. Alport Syndrome Therapeutic Approaches
7. Alport Syndrome Pipeline Analysis
8. Alport Syndrome Current Treatment Practices/Algorithm
9. Impact of Emerging Therapies on the Alport Syndrome Market

Table of Contents
1. Key Insights
2. Executive Summary
3. Alport Syndrome Competitive Intelligence Analysis
4. Alport Syndrome Market Overview at a Glance
5. Alport Syndrome Disease Background and Overview
6. Alport Syndrome Patient Journey
7. Alport Syndrome Epidemiology and Patient Population
8. Alport Syndrome Treatment Algorithm, Current Treatment, and Medical Practices
9. Alport Syndrome Unmet Needs
10. Key Endpoints of Alport Syndrome Treatment
11. Alport Syndrome Marketed Products
12. Alport Syndrome Emerging Therapies
13. Alport Syndrome Seven Major Market Analysis
14. Attribute Analysis
15. Alport Syndrome Market Outlook (7 major markets)
16. Alport Syndrome Access and Reimbursement Overview
17. KOL Views on the Alport Syndrome Market
18. Alport Syndrome Market Drivers
19. Alport Syndrome Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer

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