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Emerging Trends Influencing The Growth Of The Inherited Retinal Disease Market: Innovation In Mutation-Agnostic Gene Therapy Shaping The Market

06-16-2025 06:57 AM CET | Health & Medicine

Press release from: The Business Research Company

Inherited Retinal Disease

Inherited Retinal Disease

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How Big Is the Inherited Retinal Disease Market Size Expected to Be by 2034?
The market size for inherited retinal diseases has seen robust growth in the past few years. It is projected to increase from $11.56 billion in 2024 to $12.58 billion in 2025, with a Compound Annual Growth Rate (CAGR) of 8.8%. Factors contributing to the growth during the historical period include the implementation of gene therapy, regulatory benefits, an increase in patient registries, more clinical trials, and the enhancement of patient-centered solutions.

Expectations are high for significant expansion of the inherited retinal disease market in the coming years. It is forecasted to reach a value of $17.42 billion in 2029, with a compound annual growth rate (CAGR) of 8.5%. This projected growth during this period can be linked to factors such as the increased application of CRISPR, the advent of personalized treatments, a concentration on regenerative medicine, the rise of patient advocacy, and a commitment to enhancing patients' quality of life. The period is also anticipated to see key trends such as the advancement of optogenetics technology, the creation of artificial retina implants, the broadening of digital health platforms, the inclusion of artificial intelligence in disease modelling, and the application of artificial intelligence in treatment planning.

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What Are the Emerging Segments Within the Inherited Retinal Disease Market?
The inherited retinal disease market covered in this report is segmented -

1) By Type: Diagnosis, Therapy
2) By Disease Type: Retinitis Pigmentosa, Choroideremia, Stargardt Disease, Cone-rode Dystrophy, Leber Congenital Amaurosis, Other Diseases
3) By Distribution Channel: Retail Sales, Direct Tender
4) By End Users: Hospitals, Speciality Clinics, Ambulatory Surgical Centres, Home Healthcare, Other End Users

Subsegments,
1) By Diagnosis: Genetic Testing (Genetic Screening), Retinal Imaging (Fundus Photography, Optical Coherence Tomography (OCT)), Electrophysiological Testing (Electroretinography), Visual Field Testing, Fundus Autofluorescence Imaging
2) By Therapy: Gene Therapy, Stem Cell Therapy, Retinal Prosthesis (Artificial Retina), Pharmacological Therapy (Gene Editing, Retinal Drugs), Photoreceptor Rescue Therapy

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What Long-Term Drivers Are Shaping Inherited Retinal Disease Market Trends?
The inherited retinal disease market is expected to surge as macular degeneration becomes more prevalent. This age-linked eye disorder that impairs the macula leads to central vision loss and impedes activities like reading or facial recognition. The surge in macular degeneration can be attributed to an aging population, increased life expectancy, and lifestyle habits such as smoking and inadequate nutrition that heighten risk. Treatment of inherited retinal disease aids patients with macular degeneration by focusing on the genetic roots of retinal degeneration. This offers therapies that slow down the disease's advancement, restore lost vision, and potentially prevent additional retina damage, ultimately enhancing visual outcomes and the life quality of individuals afflicted by age-related or inherited macular degeneration. For example, the Canadian Ophthalmological Society, a nonprofit residing in Canada, documented in February 2024 that 2.5 million Canadians over the age of 55 lost their eyesight due to age-related macular degeneration (AMD). This surge in macular degeneration cases is a driving force for the inherited retinal disease market's growth.

Who Are the Top Competitors in Key Inherited Retinal Disease Market Segments?
Major companies operating in the inherited retinal disease market are Johnson & Johnson, Novartis AG, Astellas Pharma Inc., Biogen Inc., Vertex Pharmaceuticals Inc., Ionis Pharmaceuticals Inc., Invitae Corporation, Spark Therapeutics, Aldeyra Therapeutics, Regenxbio Inc., IVERIC bio, MeiraGTx Limited, Ocugen Inc., Coave Therapeutics, Bionic Vision Technologies, GenSight Biologics SA, LKC Technologies Inc., Sparing Vision, ProQR Therapeutics NV, Endogena Therapeutics

What Actigraphy Devices Market Trends Are Gaining Traction Across Different Segments?
Leading companies in the inherited retinal diseases marketplace are concentrating on the development of groundbreaking treatments such as mutation-agnostic gene therapy. This strategy aims to provide comprehensive care and address various genetic mutations associated with these diseases. Unlike targeted genetic treatments, Mutation-agnostic gene therapy targets larger genetic mechanisms, proving useful across a spectrum of genetic disorders. For instance, Nanoscope Therapeutics Inc, a biotech company from the US, broadcasted positive findings from a clinical trial involving their main program, MCO-010 in March 2024. The program showed improvements in vision for those suffering from advanced retinitis pigmentosa, leading to severe and permanent vision loss. MCO-010 met its primary and important secondary objectives while demonstrating statistical significance and encountering no severe side effects.

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Which Regions Are Becoming Hubs for Inherited Retinal Disease Market Innovation?
North America was the largest region in the inherited retinal disease market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the inherited retinal disease market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

Frequently Asked Questions:
1. What Is the Market Size and Growth Rate of the Inherited Retinal Disease Market?
2. What is the CAGR expected in the Inherited Retinal Disease Market?
3. What Are the Key Innovations Transforming the Inherited Retinal Disease Industry?
4. Which Region Is Leading the Inherited Retinal Disease Market?

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