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Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market Forecast 2025-2034: Comprehensive Analysis And Growth Opportunities
Adeno-Associated Virus (AVV) Vectors In Gene Therapy
What Is the Projected Growth of the Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market?
In recent years, the market size for adeno-associated virus (AVV) vectors in gene therapy has seen significant growth. The market which was worth $2.70 billion in 2024, is projected to expand to $3.18 billion in 2025, exhibiting a compound annual growth rate (CAGR) of 17.7%. This considerable growth during the historic period is largely due to factors such as increased funding for gene therapy research, rising acceptance of gene editing technologies, prevalence of genetic disorders and unfulfilled medical needs. There's also been an escalating demand for targeted therapies, as well as an increase in partnerships between biotech firms and research organisations.
Swift development is anticipated in the adeno-associated virus (AVV) vectors gene therapy market over the coming years, with a projected market value expected to reach $6.09 billion in 2029, showcasing a compound annual growth rate (CAGR) of 17.6%. This growth can be accredited to advancements in AAV capsid engineering, the prevalent focus on precision medicine, the rising investment in genetics and biotechnology research, an increase in approved gene therapy clinical trials, and a growing demand for personalized medical treatment. Trends to look out for in the upcoming period include progress in artificial intelligence for AAV capsid engineering, creation of hybrid AAV vectors for carrying larger genetic payloads, innovations in bispecific antibody-mediated AAV targeting, advancements in scalable AAV production and purification methods, and the development of adaptable AAV platforms that cater to a variety of viral vectors.
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What Are the Different Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market Segments?
The adeno-associated virus (AVV) vectors in gene therapy market covered in this report is segmented -
1) By Type of Therapy: Gene Augmentation, Immunotherapy, Other Type of Therapy
2) By Type of Gene Delivery Method Used: Ex Vivo, In Vivo
3) By Scale of Operation: Preclinical, Clinical, Commercial
4) By Target Therapeutic Area: Genetic Disorders, Hematological Disorders, Infectious Diseases, Metabolic Disorders, Ophthalmic Disorders, Muscle Disorders, Neurological Disorders, Other Target Therapeutic Area
Subsegments:
1) By Gene Augmentation: Monogenic Disorders, Neurological Disorders, Muscular Disorders, Ophthalmological Disorders, Metabolic Disorders
2) By Immunotherapy: Oncology, Infectious Diseases, Autoimmune Disorders, Vaccine Development, T-Cell Engineering
3) By Other Type of Therapy: Gene Editing Support, RNA Interference, Neuroprotection and Neuroregeneration, Anti-Inflammatory Applications, Regenerative Medicine
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What Are the Primary Drivers Shaping the Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market?
The escalating emphasis on therapies derived from genes is predicted to fuel the expansion of the adeno-associated virus (AAV) vector in the gene therapy market. These therapies include treatments that alter genes to prevent, cure, or manage diseases at the cellular level. The enhancement in precision and efficiency of gene manipulation techniques is attributed to the advancements in genetic studies. In gene therapy, adeno-associated virus (AAV) vectors aid in the creation of gene-based therapies. They effectively and safely deliver therapeutic genes into target cells due to their low likelihood of causing an immune response and potential for long-term gene expression. For example, IQVIA, an American organization offering advanced analytic and technological solutions for the life sciences industry, reported that global expenditure on cell and gene therapies soared to $5.9 billion in 2023, marking a 38% rise from 2022. Hence, the surging emphasis on the development of gene-based therapies is propelling the growth of the adeno-associated virus (AAV) vectors market.
Which Companies Are Leading in the Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market?
Major companies operating in the adeno-associated virus (AVV) vectors in gene therapy market are F. Hoffmann-La Roche Ltd., Sanofi S.A., Novartis AG, Astellas Gene Therapies Inc., Biogen Inc., Sarepta Therapeutics Inc., Oxford BioMedica plc, Rocket Pharmaceuticals Inc., Aldevron LLC, REGENXBIO Inc., uniQure N.V., Passage Bio Inc., Voyager Therapeutics Inc., Dyno Therapeutics Inc., MeiraGTx Holdings plc, Abeona Therapeutics Inc., 4D Molecular Therapeutics Inc., GenSight Biologics S.A., Taysha Gene Therapies Inc., LogicBio Therapeutics Inc.
What Are the Major Trends Shaping the Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market?
Leading firms operating in the adeno-associated virus (AAV) vectors domain within the gene therapy market are channeling their focus toward ground-breaking innovations. These include specially-tailored vector diversity for assay versatility to boost target tissue specificity, enhance therapeutic efficacy, and hasten the development of personalised gene therapies for a wide range of indications. Tailored vector diversity for assay versatility essentially involves utilising various AAV serotypes or constructs to cater to a myriad of analytical tests and therapeutic applications. For instance, in May 2024, Charles River Laboratories, a pharmaceutical firm based in the US, revealed new reference materials for adeno-associated virus (AAV) and lentiviral vectors (LVV). These materials have been created to meet the escalating demands of cell and gene therapy (CGT) development. This range facilitates a seamless progression from preliminary research to GMP-grade production, standardises processes, and enhances consistency in viral vector manufacturing. This launch thus caters to a crucial challenge in escalating CGT programmes toward clinical and commercial readiness.
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What Are the Top Revenue-Generating Geographies in the Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market?
North America was the largest region in the adeno-associated virus (AVV) vectors in gene therapy market in 2024. The regions covered in the adeno-associated virus (AVV) vectors in gene therapy market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
Frequently Asked Questions:
1. What Is the Market Size and Growth Rate of the Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market?
2. What is the CAGR expected in the Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market?
3. What Are the Key Innovations Transforming the Adeno-Associated Virus (AVV) Vectors In Gene Therapy Industry?
4. Which Region Is Leading the Adeno-Associated Virus (AVV) Vectors In Gene Therapy Market?
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