Press release
Gene Silencing Industry Report 2025-2034: Market Dynamics, Trends, And Forecasts
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What Is the Expected Gene Silencing Market Size During the Forecast Period?_x000D_
The size of the gene silencing market has expanded at a swift pace over the past few years. Its growth will see an increase from $5.97 billion in 2024 to $6.75 billion in 2025, with a compound annual growth rate (CAGR) of 13.0%. This substantial growth during the historical period can be ascribed to the burgeoning research in genetic therapies, preliminary RNA interference breakthroughs, a surge in the occurrence of genetic disorders, escalated investments in biotechnology, and the expansion of biopharmaceutical manufacturing potential._x000D_
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The market for gene silencing is anticipated to experience significant expansion in the coming years, estimated to reach a value of $10.95 billion by 2029, growing at a compound annual growth rate (CAGR) of 12.9%. The predicted surge during the forecast period could be due to the widening scope of applications in rare diseases, advances in delivery systems technology, burgeoning demand for personalized medicine, facilitating government programs, and increasing collaborations between pharmaceutical and biotech enterprises. Some noteworthy trends for the forecast period encompass the advent of focused gene therapies, the emergence of CRISPR-based silencing techniques, an increased emphasis on rare and orphan diseases, the breakthrough of nanoparticle delivery methods, and growing involvement in agriculture-related gene silencing applications._x000D_
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What Are the High-Growth Segments in the Gene Silencing Market?_x000D_
The gene silencing market covered in this report is segmented -_x000D_
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1) By Type: Transcriptional, Post-Transcriptional, Meiotic_x000D_
2) By Gene Silencing: RNA Interference (RNAi), Antisense Oligonucleotides (ASOs), Clustered Regularly Interspaced Short Palindromic Repeats(CRISPR) Or Cas9 -Based Gene Silencing, Other Gene Silencings_x000D_
3) By Application: Neurology, Oncology, Infectious Diseases, Metabolic Diseases, Therapeutics Manufacturing, Other Applications_x000D_
4) By End-Users: Pharmaceutical And Biotechnology Companies, Research Institutes and Academic Centers, Hospitals, Clinics, Other End-Users_x000D_
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Subsegments:_x000D_
1) By Transcriptional: DNA Methylation, Histone Modification_x000D_
2) By Post-Transcriptional: RNA Interference (RNAi), Antisense Oligonucleotides, MicroRNA (miRNA) Mediated Silencing_x000D_
3) By Meiotic: Meiotic Gene Conversion, Transposable Element Silencing_x000D_
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What Key Drivers Are Expected to Influence Future Gene Silencing Market Growth?_x000D_
The anticipated growth of the gene silencing market is commonly linked to the increasing instances of genetic disorders. Genetic disorders, which are health conditions prompted by DNA abnormalities in an individual, are being recognized more frequently. This increasing identification is a result of advances in diagnostic technology, a rise in awareness and wider access to genetic testing. Factors such as rising parental age contribute to higher rates of genetic disorders, as this heightens the risk of passing genetic mutations to offspring. Gene silencing represents a potential treatment involving the selective halting of expression of defective or disease-causing genes. As an illustration from August 2023, approximately 1 in every 800 newborns in the UK is affected by Down Syndrome according to Down Syndrome UK, a domestic nonprofit organization. Meanwhile, an estimated 40,000 individuals in the UK are affected by this disorder. Thus, it is the higher incidence of genetic disorders that is boosting the expansion of the gene silencing market._x000D_
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Which Companies Hold the Largest Share Across Different Gene Silencing Market Segments?_x000D_
Major companies operating in the gene silencing market are Roche Holding AG, Merck & Co. Inc., AstraZeneca plc, Novartis International AG, Thermo Fisher Scientific Inc., Danaher Corporation, Agilent Technologies Inc., Illumina Inc., Bio-Rad Laboratories Inc., Bio-Techne Corporation, Alnylam Pharmaceuticals Inc., GenScript Biotech Corporation, Oxford BioMedica plc, Ionis Pharmaceuticals Inc., Arrowhead Pharmaceuticals Inc., Dicerna Pharmaceuticals Inc., New England Biolabs Inc., Quark Pharmaceuticals Inc., Sirion Biotech GmbH, Benitec Biopharma Limited, GeneCopoeia Inc., Revvity Inc._x000D_
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What Trends Are Expected to Dominate the Gene Silencing Market in the Next 5 Years?_x000D_
Leading firms in the gene silencing market are prioritizing the development of groundbreaking technologies like small interfering RNA (siRNA) to increase precision and effectiveness in gene therapy. Small interfering RNA (siRNA) is an RNA molecule that holds an essential role in the RNA interference (RNAi) pathway. It binds to specific messenger RNA (mRNA) and facilitates its degradation, stopping the creation of proteins that cause diseases. For example, in October 2024, Judo Bio Inc., a biotechnology firm based in the United States, introduced siRNA, a new generation drug that employs small interfering RNA (siRNA) to suppress genes. The drug stands out for its unique features such as proprietary delivery systems like lipid nanoparticles or conjugated ligands, ensuring efficient absorption by certain cells or tissues, and AI-powered platforms hastening the finding of feasible gene targets._x000D_
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What Are the Emerging Geographies for The Gene Silencing Market Growth?_x000D_
North America was the largest region in the gene silencing market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the gene silencing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa._x000D_
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Frequently Asked Questions:_x000D_
1. What Is the Market Size and Growth Rate of the Gene Silencing Market?_x000D_
2. What is the CAGR expected in the Gene Silencing Market?_x000D_
3. What Are the Key Innovations Transforming the Gene Silencing Industry?_x000D_
4. Which Region Is Leading the Gene Silencing Market?_x000D_
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Why This Report Matters:_x000D_
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