openPR Logo
Press release

mRNA Synthesis and Manufacturing Market Poised for Transformation, Says Roots Analysis

06-10-2025 03:25 PM CET | Health & Medicine

Press release from: Roots Analysis

mRNA Synthesis and Manufacturing Market Poised

In a world still recovering from the COVID-19 pandemic, the spotlight on mRNA technology has never been brighter. Remember the scramble for vaccines in 2020? The rapid development of mRNA-based vaccines like COMIRNATY and Spikevax not only changed the course of the pandemic but also set the stage for a new era in medicine. Now, as the dust settles, Roots Analysis has released a comprehensive report on the mRNA Synthesis and Manufacturing Market, offering a roadmap for the future of this revolutionary field.

A Market in Flux

According to Roots Analysis, the global mRNA synthesis and manufacturing market is expected to be worth USD 1.06 billion in 2024. But here's the twist: by 2035, the market is projected to shrink to USD 0.58 billion. This unexpected trajectory is sparking conversations among industry insiders and investors alike. What's behind this shift? The answer lies in a complex interplay of technological advancements, market saturation, and evolving therapeutic applications.

To request quote of this report, please visit:
https://www.rootsanalysis.com/reports/mrna-synthesis-and-manufacturing-market/request-quote.html

Why the Decline?

At first glance, a shrinking market might seem like bad news. But dig deeper, and you'll find a story of maturation and efficiency. The initial boom was fueled by the urgent need for COVID-19 vaccines. Now, as demand stabilizes and production processes become more streamlined, costs are dropping. Companies are also facing challenges around stability, purity, and regulatory compliance, which are pushing them to innovate or exit the market.

The Players and the Playbook

The competitive landscape is as dynamic as the technology itself. Over 40 companies-ranging from industry giants to nimble startups-are vying for a piece of the pie. Around half of these players offer contract services for both drug substance (mRNA) and drug product (mRNA-based vaccines and therapeutics). Notable names include Aldevron, Merck KGaA, Thermo Fisher Scientific, and WuXi Biologics.

In November 2023, TriLink BioTechnologies made waves by launching its Analytical Sciences Center of Excellence, expanding its analytical testing capabilities. This move underscores the industry's focus on quality and innovation.

Kits, Customization, and Collaboration

The market is also rich with options for researchers. Over 95 mRNA synthesis kits are available, with about half containing all the necessary components-enzyme mix, buffers, and reagents. Most of these kits feature capping enzymes, a critical component for mRNA stability and efficacy.

Collaboration is the name of the game. Since 2019, more than 70 deals have been struck, primarily manufacturing agreements. Big pharma players are actively pursuing partnerships, acquisitions, and funding rounds to bolster their mRNA portfolios.

To request a sample copy / brochure of this report, please visit
https://www.rootsanalysis.com/reports/mrna-synthesis-and-manufacturing-market/request-sample.html

Beyond Vaccines: A Therapeutic Revolution

While mRNA's star rose with vaccines, its potential extends far beyond infectious diseases. Researchers are exploring applications in autoimmune disorders, genetic diseases, and even cancer. This expansion is driving demand for high-quality raw materials and advanced manufacturing services.

Regional Dynamics

North America continues to dominate the market, a trend expected to persist through 2024 and beyond. Europe and Asia-Pacific are also significant players, but North America's lead is bolstered by a concentration of established firms and cutting-edge research facilities.

Key Takeaways at a Glance
1. Market Size: USD 1.06 billion in 2024, projected to drop to USD 0.58 billion by 2035.
2. Key Players: Over 40 companies, including Aldevron, Merck KGaA, and Thermo Fisher Scientific.
3. Kits and Services: More than 95 mRNA synthesis kits available; over 35 custom synthesis service providers globally.
4. Therapeutic Expansion: Applications now include vaccines, autoimmune disorders, genetic diseases, and cancer.
5. Regional Focus: North America leads, followed by Europe and Asia-Pacific.
6. Innovation: Companies are investing in quality, analytics, and partnerships to stay competitive.

Browse Full Report Description + Research Methodology + Table of Content + Infographics here:
https://www.rootsanalysis.com/reports/mrna-synthesis-and-manufacturing-market.html

A Personal Reflection

As someone who witnessed the frantic search for vaccines during the pandemic, it's remarkable to see how far mRNA technology has come. What started as a race against time has evolved into a sophisticated, global industry. The challenges are real-stability, scalability, and regulatory hurdles-but so are the opportunities. The next chapter in mRNA's story will be written by those who can balance innovation with reliability, and ambition with caution.

Stay tuned a
Thank you for reading Roots Analysis report. Kindly get in touch with Roots' team to know more about the report or to receive a customized copy of it. Our team will ensure the report is tailored according to your needs.

Roots Analysis
Gaurav Chaudhary
+1 (857) 387 7999
+44 (748) 188 1310
Gaurav.chaudhary@rootsanalysis.com
Website: https://www.rootsanalysis.com/

Roots Analysis is a global leader in market research, competitive intelligence and consulting services across industries. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, and venture and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights. All reports provided by us are structured in a way that enables the reader to develop a thorough perspective on the given subject. Apart from writing reports on identified areas, we provide bespoke research / consulting services dedicated to serving our clients in the best possible way.

This release was published on openPR.

Permanent link to this press release:

Copy
Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.

You can edit or delete your press release mRNA Synthesis and Manufacturing Market Poised for Transformation, Says Roots Analysis here

News-ID: 4059954 • Views:

More Releases from Roots Analysis

DNA Data Storage Market Set for Explosive Growth, Says Roots Analysis
DNA Data Storage Market Set for Explosive Growth, Says Roots Analysis
Imagine a world where the entire contents of the Library of Congress could fit into a drop of liquid-and last for thousands of years. That's the promise of DNA data storage, a technology that's rapidly moving from science fiction to reality. According to a new report from Roots Analysis, the DNA data storage market is poised for dramatic expansion, with a projected compound annual growth rate (CAGR) of 28% through
Rare Kidney Disease Market Set to Surge, Fueled by Innovation and Investment
Rare Kidney Disease Market Set to Surge, Fueled by Innovation and Investment
Imagine a world where a rare diagnosis no longer means limited treatment options. For patients grappling with rare kidney diseases-conditions often overlooked in mainstream medicine-that future is closer than ever. According to a comprehensive new report from Roots Analysis, the rare kidney disease market is poised for remarkable growth, driven by scientific breakthroughs, robust investment, and a wave of new therapies entering clinical trials. To request quote of this report, please
Manufacturing Execution System Market Set to Soar to $20.46 Billion by 2035
Manufacturing Execution System Market Set to Soar to $20.46 Billion by 2035
The manufacturing world is on the brink of a technological revolution, and at the heart of this transformation lies the Manufacturing Execution System (MES) market. According to a comprehensive new report by Roots Analysis, the global MES market is expected to skyrocket from a valuation of USD 3.99 billion in 2024 to an impressive USD 20.46 billion by 2035, growing at a robust compound annual growth rate (CAGR) of 16.02%.
What Are Digital Biomarkers and Why Do They Matter?
What Are Digital Biomarkers and Why Do They Matter?
The digital biomarkers market is on the cusp of a remarkable transformation, poised to revolutionize how we understand and manage health. According to a comprehensive new report by Roots Analysis, this market is expected to soar from an estimated USD 5.6 billion in 2024 to a staggering USD 35.8 billion by 2035, growing at a robust compound annual growth rate (CAGR) of 18.5%. This growth story is not just about

All 5 Releases


More Releases for Synthesis

Cosmetic Peptide Synthesis Market to Witness Huge Growth by Key Players: GenScri …
The Cosmetic Peptide Synthesis research report studies primary and secondary research in order to analyze the data effectively. The market study further also draws attention to crucial industry factors such as global clients, potential customers, and sellers, which instigates positive company growth. In order to gauge the turning point of the businesses, significant market key players are also enlisted in order to deliver readers with in-depth analysis about industry strategies. The
Gene Synthesis Market : How the Gene Synthesis Market will perform in Upcoming Y …
Gene synthesis is chemically in vitro synthesis of double-stranded DNA molecules. It is a technology used in biotechnology and plays an important role in the field of synthetic biology. The technology has become a significant tool in various fields of recombinant DNA technology including gene therapy, vaccine development, molecular engineering, and heterologous gene expression. It can help in designing novel enzymes for cancer treatment. Also, it can be used in
Gene Synthesis Market Report 2018: Segmentation by Product (Gene Library Synthes …
Global Gene Synthesis market research report provides company profile for Atum, ATDBio Ltd., Bioneer Corporation, Eurofins Scientific, Eurogentec, GenScript Biotech Corporation, Genewiz, Integrated DNA Technologies, Inc. and Others. This market study includes data about consumer perspective, comprehensive analysis, statistics, market share, company performances (Stocks), historical analysis 2012 to 2017, market forecast 2018 to 2025 in terms of volume, revenue, YOY growth rate, and CAGR for the year 2018 to 2025,
Oligonucleotide Synthesis: Custom Oligonucleotide Synthesis Service Type Segment …
Research Report on "Global Market Study on Oligonucleotide Synthesis: Custom Oligonucleotide Synthesis Service Type Segment to Hold 70% Market Share by 2025". Our new research report on the global oligonucleotide synthesis market gives a brief overview of the global market. The report includes projections on the global oligonucleotide synthesis market revenue growth and the factors likely to impact this growth during the period of forecast. The report describes the scenario of
Synbio Technologies Revolutionizes DNA Synthesis
DNA Synthesis Definition and Methods DNA synthesis definition DNA synthesis is defined as the process by which copies of nucleic acids are strung together to form a longer DNA sequence within a laboratory setting. DNA synthesis processes DNA oligomers are the foundation of the DNA synthesis process. The essential feature of DNA synthesis is that no naturally isolated DNA is used. This step deviates from the traditional method of studying genetics, by which a
Advancements in technologies have enabled Bio-Synthesis to expand their product …
Bio-Synthesis offers long oligo synthesis and gene synthesis services as control templates, cloning, mutagenesis, gene expression and other demanding applications. BSI has provided thousands of high-fidelity synthesis of very long oligos, DNA UbermersTM, with impeccable quality and services which are unmatched by other suppliers. Longer constructs that required more choices like palindromes for restriction enzymes give researchers more flexibility. DNA UbermersTM are also used as an internal control template with