Press release
Global Colloids Blood Plasma Market Poised for Substantial Growth Through 2033
Rising Demand for Volume Expansion Therapies Drives Market EvolutionThe global colloids blood plasma market is experiencing unprecedented growth, driven by increasing surgical procedures, rising chronic disease prevalence, and expanding therapeutic applications in critical care medicine. The colloids blood plasma market was valued at approximately USD 5.1 billion in 2023, with projections for growth to USD 9.2 billion by 2033, representing a CAGR of 6.0% from 2024 to 2033.
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Understanding Colloids in Blood Plasma
Colloids represent a critical component of modern medical therapy, functioning as volume expanders that maintain blood pressure and circulation during critical medical situations. The liquid portion of whole blood, which makes up to 60% of the total blood volume and contains proteins including serum fibrinogen, albumins, and globulins, is known as colloids (blood plasma). These sophisticated solutions offer superior volume expansion capabilities compared to traditional crystalloid alternatives.
Market Segments and Applications
Product Categories
The market encompasses two primary segments:
Natural Type Colloids: Including human albumin solutions, fresh frozen plasma, and plasma protein fractions that leverage naturally occurring blood components for therapeutic applications.
Synthetic Type Colloids: Comprising hydroxyethyl starches, gelatins, and dextrans designed to replicate the beneficial properties of natural plasma proteins while offering enhanced stability and availability.
Therapeutic Applications
The market serves diverse medical applications:
Extensive Burns: Volume replacement for patients experiencing significant fluid loss
Massive Blood or Plasma Loss: Emergency interventions during traumatic injuries and surgical procedures
Hypovolemic Shock: Critical care management for patients experiencing dangerous drops in blood volume
Surgical Procedures: Routine volume maintenance during elective and emergency operations
Surgeries often require volume replacement to maintain blood pressure and circulation, whether elective or emergency. Colloids are preferred in surgical settings due to their rapid plasma volume expansion capabilities.
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Key Market Drivers
Growing Surgical Volume
The September 2020 research report titled "Estimation of the National Surgical Needs in India by Enumerating the Surgical Procedures in an Urban Community Under Universal Health Coverage" projected that over 11% of the global disease burden necessitated surgical or anesthetic treatment. This expanding surgical landscape directly correlates with increased demand for effective volume expansion solutions.
Chronic Disease Epidemic
The prevalence of chronic diseases significantly influences the colloids market for blood plasma products. Chronic conditions like cardiovascular diseases, kidney disorders, and liver ailments often lead to complications that require volume expansion and stabilization through colloids. The Centers for Disease Control and Prevention (CDC) estimate that 6 out of 10 individuals in America have one or more chronic illnesses, and that 4 out of 10 persons have two or more.
Innovation in Plasma-Derived Therapeutics
The need for plasma-derived medicines, including as immunoglobulins, albumin, and factor VIII, to treat a range Primary immunodeficiency illnesses, autoimmune disorders, and haemophilia are among the problems that are treated with plasma-derived treatments. This diversification of applications continues to expand market opportunities.
Leading Industry Players
The colloids blood plasma market features several established pharmaceutical companies driving innovation and market expansion:
CSL Behring: A global leader in plasma-derived and recombinant therapies with extensive research and development capabilities.
Grifols: Specializing in plasma medicines with a comprehensive portfolio of albumin and immunoglobulin products.
Octapharma: Focusing on human proteins from human plasma and human cell lines for therapeutic use.
Biotest: Developing and marketing immunoglobulins, albumin, and coagulation products derived from human plasma.
Kedrion: Manufacturing plasma-derived therapeutics for treating rare and severe diseases globally.
These companies have invested heavily in research and development and are constantly innovating to produce new and improved products.
Recent Market Developments
Regulatory Approvals and Product Launches
In May 2020, Bio Products Laboratory (BPL), a prominent producer of plasma-derived protein therapies, introduced ALBUMINEX 5% (human albumin) solution for injection and ALBUMINEX 25% (human albumin) solution for injection in the US. These products received FDA approval for treating multiple conditions including hypovolemia, burns, and acute respiratory distress syndrome.
In July 2023, Kedrion Biopharma, a global biopharmaceutical company that focuses on manufacturing and distributing plasma-derived therapeutic products for the treatment of rare and severe diseases, announced that China's National Institutes for Food and Drug Control (NIFDC) had approved for the release of BPL's human Albumin product in the Chinese market.
Regional Market Analysis
North America Dominance
North America is estimated to hold the largest colloids (blood plasma) market share due to several factors including advanced healthcare infrastructure, high surgical volumes, and strong regulatory frameworks supporting product development and adoption.
Asia-Pacific Growth Potential
The Asia-Pacific region represents significant growth opportunities driven by expanding healthcare systems, increasing surgical procedures, and growing awareness of advanced treatment options for critical care management.
Market Outlook and Future Trends
Technology Integration
The market is witnessing increased integration of advanced manufacturing technologies and quality control systems to ensure product safety and efficacy. Enhanced purification processes and synthetic alternatives are expanding treatment options while addressing supply chain challenges.
Supply Chain Optimization
The global market for colloids was already facing a shortage of supply prior to the pandemic. With the pandemic, the demand is now much greater. Industry stakeholders are implementing strategic initiatives to optimize plasma collection, processing, and distribution networks.
Safety and Efficacy Focus
Ongoing research continues to refine colloid formulations, addressing historical concerns about allergic reactions and side effects while maximizing therapeutic benefits for patients requiring volume expansion therapy.
Challenges and Opportunities
Market Challenges
The industry faces several challenges including regulatory complexity, supply chain constraints, and the need for specialized storage and handling requirements. Additionally, competition from alternative volume expansion therapies requires continuous innovation and differentiation.
Growth Opportunities
Emerging markets present substantial growth opportunities as healthcare infrastructure develops and access to advanced therapies expands. The increasing prevalence of chronic diseases and aging populations worldwide create sustained demand for effective volume expansion solutions.
Conclusion
The global colloids blood plasma market stands at a pivotal juncture, with robust growth projections supported by fundamental demographic and medical trends. As surgical procedures increase globally and chronic disease management becomes increasingly sophisticated, the demand for effective volume expansion therapies continues to accelerate. Leading industry players are well-positioned to capitalize on these trends through continued innovation, strategic expansion, and commitment to patient safety and therapeutic efficacy.
The market's evolution reflects broader trends in modern medicine toward personalized, evidence-based treatments that improve patient outcomes while optimizing healthcare resource utilization. With strong regulatory support, advancing technology, and expanding global access to healthcare, the colloids blood plasma market is positioned for sustained growth and continued therapeutic advancement.
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