Press release
Gene Silencing Market to Reach USD 35.77 billion by 2034, Growing at 13.7% CAGR
Gene Silencing Market
According to recent market estimates, the gene silencing market is expected to grow from USD 9.93 billion in 2024 to USD 35.77 billion by 2034, registering a compound annual growth rate (CAGR) of 13.7% over the forecast period.
Market Introduction
Gene silencing is a relatively modern therapeutic approach that harnesses the body's natural biological processes to treat diseases by suppressing or silencing specific genes associated with particular conditions. This technique involves selectively blocking the expression of a gene's message (usually mRNA), which would otherwise lead to harmful effects in the body.
Several gene silencing techniques exist, with RNA interference (RNAi) being one of the most prominent. RNAi is a natural mechanism found in all humans and plays a key role in regulating gene activity and defending the body against viruses by degrading targeted mRNA molecules before they can be translated into proteins.
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Factors Fueling Market Growth
Growing Cases of Genetic Disorders: The growing global cases of genetic disorders, including chronic illnesses, are a notable market driver. Several impairing conditions involving cystic fibrosis, Huntington's disease, various cancers, and neurodegenerative illnesses are entrenched in genetic mutations or dysregulation. Gene silencing technologies such as RNA interference (RNAi) and antisense oligonucleotides (ASOs) provide a targeted approach to address these primary genetic issues, spiralling the gene silencing market growth.
Technological Progressions: Ongoing technological progressions in RNA-based therapeutics and their delivery systems are a prominent driver of the market. The advancement of more steady and productive RNA molecules, together with inventive delivery mechanisms, has notably improved the therapeutic possibility of gene silencing.
Competitive Landscape
The market is highly competitive, with a large number of manufacturers and retailers operating on a global scale. Some of the key players currently dominating the market include:
• Alnylam Pharmaceuticals, Inc.
• Arrowhead Pharmaceuticals, Inc.
• Silence Therapeutics PLC
• Ionis Pharmaceuticals, Inc.
• Sarepta Therapeutics, Inc.
• Intellia Therapeutics, Inc.
• CRISPR Therapeutics AG
• Editas Medicine, Inc.
• Thermo Fisher Scientific Inc.
• Merck KGaA
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Gene Silencing Market Report Highlights:
📚 By services, the products segment, encompassing RNAi, CRISPR-Cas9, antisense oligonucleotides, and others, currently holds the largest market share in the gene silencing market due to the established use and commercial availability of these tools, particularly RNAi-based products for both research and therapeutic development.
📚 By application, the drug discovery & development segment currently accounts for the largest market share as gene silencing technologies are extensively used as fundamental tools for understanding gene function and identifying potential drug targets in preclinical research.
📚 By end use, pharmaceutical & biotechnology companies represent the largest end-user segment in the gene silencing market, driven by their extensive research and development activities in creating novel gene silencing-based therapeutics for a wide range of diseases and their capacity for clinical trials and commercialization.
📚 By region, North America currently holds the largest share of the global gene silencing market. The Asia Pacific region is projected to exhibit the highest growth rate in the gene silencing market over the forecast period.
Regional Insights
North America holds the largest market share owing to the region's robust biotechnology, pharmaceutical, and life sciences industries, notable government and private funding for research and development, and an entrenched regulatory framework. The rising prevalence of genetic diseases and chronic illnesses in North America also drives the demand for gene silencing technologies.
Asia Pacific is projected to exhibit the fastest growth rate due to growing funding in life sciences research, a speedily growing biopharmaceutical industry, and a rising aging population base.
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Segmental Outlook
Gene Silencing Market, Service Outlook (Revenue - USD Billion, 2020-2034)
• Products
» RNAi
» CRISPR-Cas9
» Antisense Olignucleotides
» Others
• Services
Gene Silencing Market, Applications Outlook (Revenue - USD Billion, 2020-2034)
• Drug Discovery & Development
• Therapeutics Manufacturing
• Agricultural Applications
• Others
Gene Silencing Market, End-use Outlook (Revenue - USD Billion, 2020-2034)
• Pharmaceutical & Biotechnology Companies
• Academic & Research Institutes
• CROs & CMOs
• Others
Frequently Asked Questions (FAQs)
1. What are the key statistics for the gene silencing market?
2. What is the current growth rate of the gene silencing market?
3. Which region held the largest share of the gene silencing market in 2024?
4. Who are the leading players in the gene silencing market?
5. Which end-use segment accounted for the largest market share in 2024?
6. What are the emerging trends and future opportunities in the gene silencing market?
7. What is gene silencing?
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