Press release
G-Protein Coupled Receptors Market Projected to Hit USD 6,965.93 Million by 2034 | CAGR: 6.02%
The market for G-protein coupled receptors is poised to witness sustained growth, according to the latest market research by Polaris Market Research. The market was valued at USD 3,886.23 million in 2024 and is projected to grow to USD 6,965.93 million by 2034. It is anticipated to exhibit a CAGR of 6.02% during 2025-2034.
Market Introduction
G-protein coupled receptors (GPCRs) are a are a large and diverse group of membrane proteins. These receptors play a crucial role in transmitting signals from the outside to the inside of a cell. They are embedded the cell membrane and are activated by a wide variety of external stimuli, such as odors, light, neurotransmitters, hormones, and mechanical stress. Once activated, these reports interact with intracellular G-proteins, triggering a cascade of signaling pathways inside the cell. This, in turn, influences cellular responses such as gene expression, metabolism, cell growth, and immune function. GPCRs are crucial for human physiology and are implicated in numerous diseases, which makes them one of the most important drugs in modern medicine.
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Market Drivers
Increasing Prevalence of Chronic and Lifestyle-Related Diseases: GPCRs play a critical role in regulating several important biological pathways. This makes them valuable targets for therapeutic interventions in chronic and lifestyle-related diseases such as cardiovascular disorders, diabetes, and respiratory illnesses. The demand for effective targeted therapies like GPCRs is growing as the global burden of chronic diseases continues to rise.
Advancements in Drug Discovery Technologies:
Advancements like structure-based drug design and high-throughput screening have greatly enhanced the ability to identify and optimize GPCR-targeted compounds. These technological advancements are enabling researchers to predict drug efficacy and better understand receptor behavior. As a result, innovations in drug discovery technologies are strengthening the pipeline of GPCR-targeted therapeutics.
G-Protein Coupled Receptors Market Report Highlights
• In terms of product, the cell lines segment led the GPCR market share in 2024, due to their reliability in creating standardized models for GPCR functional studies and high-throughput drug screening applications.
• Based on assay type, the cAMP functional assays segment is poised for significant expansion, as these tests remain crucial for quantifying GPCR-mediated intracellular signaling with high sensitivity and precision.
• North America accounted for the largest market revenue share, supported by advanced research facilities, substantial drug discovery funding, and dense biopharma industry clustering.
• The Asia Pacific market is anticipated to exhibit the highest growth rate during the forecast period, fueled by increasing healthcare expenditures, pharmaceutical sector expansion, and intensified R&D focus.
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Competitive Landscape
The G-protein coupled receptors market has the presence of both leading companies and emerging startups. A few of the major market participants include:
• Alomone Labs
• Abcam plc
• Cisbio (Revvity)
• Confo Therapeutics
• DiscoverX (Eurofins)
• Eurofins Scientific
• Heptares Therapeutics (Sosei Group)
• Merck KGaA
• Molecular Devices
• PerkinElmer Inc.
• Promega Corporation
• Sartorius (BellBrook Labs)
• Tango Biosciences
• Thermo Fisher Scientific Inc.
• WuXi AppTec
Segmental Analysis
G-Protein Coupled Receptors Market, Product Outlook (Revenue - USD Million, 2020-2034)
• Cell Lines
• Detection Kits
• Cell Culture Reagents
• Ligands
G-Protein Coupled Receptors Market, Assay Type Outlook (Revenue - USD Million, 2020-2034)
• cAMP Functional Assays
• Calcium Functional Assays
• β-Arrestin Functional Assays
• Radioligand Binding & GTPγS Functional Assays
• Internalization Assays
• Trafficking Assays
• Others
G-Protein Coupled Receptors Market, Application Outlook (Revenue - USD Million, 2020-2034)
• Cancer Research
• CNS Research
• Metabolic Research
• Cardiovascular Research
• Respiratory Research
• Inflammation Research
• Others
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Regional Overview
• By region, the report offers G-protein coupled receptors market insights into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa.
• North America held the largest share of the global market in 2024. The regional market dominance is attributed to several factors, including the region's advanced research infrastructure and presence of leading market companies. In addition, substantial investment in drug discovery contributes to the region's leading market position.
• Asia Pacific is projected to witness the fastest growth during the forecast period. The rapid expansion is fueled by rising healthcare investments, expanding pharmaceutical industries, and increasing focus on research and development activities. In addition, growing prevalence of chronic diseases is driving the regional market growth.
• North America
o US
o Canada
• Europe
o Germany
o UK
o France
o Italy
o Spain
o Russia
o Netherlands
o Rest of Europe
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About Polaris Market Research & Consulting, Inc:
Polaris Market Research is a global market research and consulting company. The company specializes in providing exceptional market intelligence and in-depth business research services for PMR's clientele spread across different enterprises. We at Polaris are obliged to serve PMR's diverse customer base present across the industries of healthcare, technology, semiconductors, and chemicals among various other industries present around the world. We strive to provide PMR's customers with updated information on innovative technologies, high-growth markets, emerging business environments, and the latest business-centric applications, thereby helping them always to make informed decisions and leverage new opportunities. Adept with a highly competent, experienced, and extremely qualified team of experts comprising SMEs, analysts, and consultants, we at Polaris endeavor to deliver value-added business solutions to PMR's customers.
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