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Rising Smoking Rates Fueling Growth in the Primary Biliary Cholangitis Market: A Significant Driver Propelling The Primary Biliary Cholangitis Market In 2025
Primary Biliary Cholangitis Market
What Is the Primary Biliary Cholangitis Market Size and Projected Growth Rate?
The market size for primary biliary cholangitis has seen a swift expansion in the last few years. It's projected to escalate from $0.98 billion in 2024 to $1.09 billion in 2025, recording a compound annual growth rate (CAGR) of 11.8%. Factors such as heightened disease awareness, surge in worldwide health care spending, strategic partnerships within the healthcare industry, emphasis on patient representation, and governmental liver health initiatives, can all be credited for the growth experienced during the historic period.
The market size for primary biliary cholangitis is projected to experience robust gains in the near future, swaying to an expected $1.6 billion by 2029, with an annual average growth rate (CAGR) of 9.9%. This forecasted surge is a result of factors including the expansion in biomarker research, worldwide initiatives in managing rare diseases, heightened collaborations in clinical trials, and a holistic approach to patient healthcare, along with the escalating need for liver transplants. Key shifts that are expected during the forecast period expand to advancements in biomarker research, a growing emphasis on non-harmful diagnostic methods, study concentration on immune-modifying treatments. Integration of artificial intelligence (AI), patient feedback outcomes incorporated in clinical trials, telemedicine for patient care, the concentration on combination therapies, and emerging treatments targeting fibrosis are also expected growth-drivers.
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What Are the Major Segments in the Primary Biliary Cholangitis Market?
The primary biliary cholangitis market covered in this report is segmented -
1) By Treatment Type: Drugs, Liver Transplantation
2) By Diagnosis: Imaging Tests, Magnetic Resonance Elastography (MRE), Magnetic Resonance Cholangiopancreatography (MRCP), Ultrasound, Fibroscan, Blood Tests, Cholesterol Test, Antibody Tests, Liver Tests, Other Diagnoses
3) By End-Users: Specialty Clinics, Homecare, Other End-Users
Subsegments:
1) By Drugs: Ursodeoxycholic Acid (UDCA), Obeticholic Acid (OCA), Fibrates, Immunosuppressive Drugs, Other Targeted Therapies
2) By Liver Transplantation: Orthotopic Liver Transplantation (OLT), Living Donor Liver Transplantation, Hepatobiliary Surgery For Liver Transplant
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What Are The Driving Primary Biliary Cholangitis Market Evolution?
The rise in smoking rates is anticipated to spark a surge in the primary biliary cholangitis market. The term 'smoking' refers to the act of inhaling and exhaling smoke resulting from the burning of tobacco or other items. Liver diseases, including PBC, have been connected to the habit of smoking. Increased smoking can thus lead to higher numbers of people seeking treatment for liver-related ailments. For instance, official data from Statistics Canada released in July 2023, revealed that cigarette production in Canada had seen a boost of 2.2% compared to June 2023. Furthermore, June witnessed a 2.6% augmentation in cigarette sales, peaking at 1.4 billion units relative to May. Hence, an increment in smoking is set to augment the growth of the primary biliary cholangitis market. The escalating number of liver cancer cases is also projected to stimulate the growth of the primary biliary cholangitis market. Liver cancer originates in the cells of the liver. The connection between primary biliary cholangitis and liver cancer is substantial due to the heightened risk of various malignancies, including cholangiocarcinoma and hepatocellular carcinoma. The increasing occurrence of the ailment and its possible complications also add to the growth of this market. As per the American Cancer Society's projections in January 2024, the U.S is speculated to witness about 41,630 fresh cases of liver cancer, with 28,000 cases in men and 13,630 in women. The report also suggested a likely death toll of around 29,840 (comprising 19,120 males and 10,720 females) due to this disease. Consequently, the rise in liver cancer cases is contributing to the expansion of the primary biliary cholangitis market.
Which Firms Dominate The Primary Biliary Cholangitis Market Segments?
Major companies operating in the primary biliary cholangitis market report are Pfizer Inc., F. Hoffmann-La Roche Ltd., Merck And Co. Inc., Novartis AG, Bristol-Myers Squibb Company, AstraZeneca PLC, GlaxoSmithKline PLC, Takeda Pharmaceutical Company, Amgen Inc., Boehringer Ingelheim International GmbH., Gilead Sciences Inc., Vertex Pharmaceuticals, Dr. Reddy's Laboratories Ltd., Amneal Pharmaceuticals LLC, Alnylam Pharmaceuticals Inc., Ionis Pharmaceuticals Inc., Intercept Pharmaceuticals Inc., Arrowhead Pharmaceuticals Inc., CureVac N.V., Sangamo Therapeutics Inc., Calliditas Therapeutics AB, NGM Biopharmaceuticals Inc., Bluebird Bio Inc., Intellia Therapeutics Inc., Albireo Pharma Inc., TARGET PharmaSolutions Inc., Genfit S.A., Editas Medicine Inc., CymaBay Therapeutics Inc., Ascletis Pharma Inc.
What Trends Are Expected to Dominate the Primary Biliary Cholangitis Market in the Next 5 Years?
Firms active in the primary biliary cholangitis market are concentrating on improving novel and targeted treatments such as orphan drugs combined with obeticholic acid (OCA) and bezafibrates to treat primary biliary cholangitis (PBC) and achieve market predominance. The aim of combining an orphan drug designation with OCA and bezafibrate is to provide a more complete and efficient method for managing PBC treatment, thus potentially enhancing the life quality of those suffering from this infrequent condition. For instance, Intercept Pharmaceuticals, Inc., a biopharmaceutical company located in the US, got orphan drug designation approval from the FDA in May 2023 for the mixture of obeticholic acid (OCA) and bezafibrate, a PPAR agonist, intended as a possible treatment for primary biliary cholangitis (PBC), a deteriorating liver disease. Also, obeticholic acid (advertised as Ocaliva) is confirmed for PBC treatment in the US.
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Which Is The Largest Region In The Primary Biliary Cholangitis Market?
North America was the largest region in the primary biliary cholangitis market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the primary biliary cholangitis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
Frequently Asked Questions:
1. What Is the Market Size and Growth Rate of the Primary Biliary Cholangitis Market?
2. What is the CAGR expected in the Primary Biliary Cholangitis Market?
3. What Are the Key Innovations Transforming the Primary Biliary Cholangitis Industry?
4. Which Region Is Leading the Primary Biliary Cholangitis Market?
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