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Gene Therapy for Blood Disorders Market Insights on Future Growth with Focus on Increasing Clinical Trials and Pipeline Therapies
Gene Therapy for Blood Disorders Market
The Gene Therapy for Blood Disorders Market Size is estimated to grow at a 15% CAGR during the forecast period for 2024-2031.
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Gene therapy involves the modification of human genes to treat various diseases and holds significant promise, particularly for rare blood disorders such as sickle cell disease and hemophilia. A growing number of biopharmaceutical companies are adopting gene-editing technologies, notably CRISPR-Cas9, to develop targeted treatments for these rare conditions. For example, CRISPR Therapeutics, in collaboration with Vertex Pharmaceuticals, is conducting Phase I/II clinical trials for CTX001, a CRISPR/Cas9-based gene therapy aimed at treating sickle cell disease.
Market growth is expected to be driven by the rising prevalence of genetic and hematologic disorders, increasing demand for personalized medicine, higher healthcare spending, and intensified research and development activities focused on innovative genetic therapies for hematology. A study published in PLOS Medicine projects a global increase of approximately 30% in sickle cell anemia cases by 2050, underscoring the growing need for effective treatment options and further fueling market expansion.
However, the high costs associated with gene therapy and concerns regarding potential side effects may pose challenges to broader market adoption over the forecast period.
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The prominent players in the gene therapy for blood disorders industry include:
BioMarin Pharmaceutical Inc. (U.S.), Medgenics (U.S.), Spark Therapeutics (U.S.), bluebird bio, Inc. (U.S.), Shire (U.S.), CRISPR Therapeutics (U.S.), Freeline Therapeutics (U.K.), OrphageniX (U.S.), Errant Gene Therapeutics (U.S.), Sangamo Therapeutics (U.S.), Sigilon Therapeutics, Inc. (U.S.), uniQure (Netherlands), Angiocrine Bioscience (U.S.), and Sanofi Genzyme (U.S.), and other prominent players.
Gene Therapy for Blood Disorders Market Regional Analysis:
North America is predicted to account for the largest share of the gene therapy for blood disorders market during the forecast years, followed by Europe, owing to the rising prevalence of various blood disorders, well-developed healthcare systems, and increasing R&D investments to develop effective gene therapies to treat rare diseases. According to the Hemophilia Federation of America, Hemophilia affects 1 in 5,000 male births, and around 400 babies are born with hemophilia in the U.S annually. Worldwide 400,000 individuals are living with hemophilia, and approximately 20,000 people are living with it in the United States alone.
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The Global Gene Therapy for Blood Disorders Market Segments
The Global Gene Therapy for Blood Disorders Market Estimates (Value US$ Million) & Forecasts and Trend Analyses, 2021 to 2030 based on Indication
• Sickle Cell Anemia
• β-thalassemia
• Hemophilia B
• Hemophilia A
• Other Indication
The Global Gene Therapy for Blood Disorders Market Estimates (Value US$ Million) & Forecasts and Trend Analyses, 2021 to 2030 based on Mechanism of Action
• Gene Therapy
• Gene Editing
The Global Gene Therapy for Blood Disorders Market Estimates (Value US$ Million) & Forecasts and Trend Analyses, 2021 to 2030 based on Region
• Europe
• North America
• Latin America
• Asia Pacific
• Middle East & Africa
North America Gene Therapy for Blood Disorders Market Estimates Revenue (US$ Million) by Country, 2021 to 2030
• U.S.
• Canada
Europe Gene Therapy for Blood Disorders Market Estimates Revenue (US$ Million) by Country, 2021 to 2030
• Germany
• Spain
• France
• Russia
• Italy
• Rest of Europe
Asia Pacific Gene Therapy for Blood Disorders Market Estimates Revenue (US$ Million) by Country, 2021 to 2030
• India
• Japan
• China
• Australia & New Zealand
• South Korea
Latin America Gene Therapy for Blood Disorders Market Estimates Revenue (US$ Million) by Country, 2021 to 2030
• Brazil
• Mexico
• Rest of Latin America
The Middle East & Africa Gene Therapy for Blood Disorders Market Estimates Revenue (US$ Million) by Country, 2021 to 2030
• South Africa
• GCC Countries
• Rest of the Middle East & Africa
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