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Atypical Hemolytic Uremic Syndrome Treatment Market Size in 7MM is expected to grow at a decent CAGR by 2034, estimates DelveInsight

05-13-2025 12:02 PM CET | Health & Medicine

Press release from: DelveInsight Business Research LLP

Atypical Hemolytic Uremic Syndrome Market

Atypical Hemolytic Uremic Syndrome Market

DelveInsight's "Atypical Hemolytic Uremic Syndrome Market Insights, Epidemiology, and Market Forecast- 2034" report delivers an in-depth understanding of the Atypical Hemolytic Uremic Syndrome, historical and forecasted epidemiology as well as the Atypical Hemolytic Uremic Syndrome market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

Discover which therapies are expected to grab the Atypical Hemolytic Uremic Syndrome Market Share @ Atypical Hemolytic Uremic Syndrome Market Outlook- https://www.delveinsight.com/sample-request/atypical-hemolytic-uremic-syndrome-ahus-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Key Takeaways from the Atypical Hemolytic Uremic Syndrome Market Report
• In May 2025, Hoffmann-La Roche announced a phase III single-arm study evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Pediatric Patients With Atypical Hemolytic Uremic Syndrome (aHUS).
• The increase in Atypical Hemolytic Uremic Syndrome Market Size is a direct consequence of the increasing patient population and anticipated launch of emerging therapies in the 7MM.
• In 2023, total diagnosed cases of aHUS in the 7MM were nearly 4,800 cases.
• In the total Atypical Hemolytic Uremic Syndrome market size in the 7MM, the United States accounted for the highest Atypical Hemolytic Uremic Syndrome market share, i.e. ~70% in 2023, followed by Germany and France.
• Among the emerging Atypical Hemolytic Uremic Syndrome therapies, Novartis (iptacopan) and Roche (crovalimab) appear to be the drugs that can potentially transform the aHUS market.
• By 2034, among the emerging Atypical Hemolytic Uremic Syndrome therapies, the highest revenue is expected to be generated by iptacopan, i.e., nearly USD 100 million in the EU4 and the UK.
• As per DelveInsight analysis, the Atypical Hemolytic Uremic Syndrome Market is anticipated to witness growth at a considerable CAGR.
• The leading Atypical Hemolytic Uremic Syndrome Companies such as Alexion Pharmaceuticals, Omeros Corporation, Novartis Pharmaceuticals, Hoffmann-La Roche, Chugai Pharmaceutical and others.
• Promising Atypical Hemolytic Uremic Syndrome Pipeline Therapies such as Eculizumab, Crovalimab, Iptacopan, Ravulizumab, OMS721, and others.

Stay ahead in the Atypical Hemolytic Uremic Syndrome Therapeutics Market with DelveInsight's Strategic Report @ Atypical Hemolytic Uremic Syndrome Market Outlook- https://www.delveinsight.com/sample-request/atypical-hemolytic-uremic-syndrome-ahus-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Atypical Hemolytic Uremic Syndrome Epidemiology Segmentation in the 7MM
• Atypical Hemolytic Uremic Syndrome Prevalence
• Age-Specific Atypical Hemolytic Uremic Syndrome Prevalence
• Gender-Specific Atypical Hemolytic Uremic Syndrome Prevalence
• Diagnosed and Treatable Cases of Atypical Hemolytic Uremic Syndrome

Download the report to understand which factors are driving Atypical Hemolytic Uremic Syndrome Epidemiology trends @ Atypical Hemolytic Uremic Syndrome Prevalence- https://www.delveinsight.com/sample-request/atypical-hemolytic-uremic-syndrome-ahus-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Marketed Atypical Hemolytic Uremic Syndrome Therapies
• ULTOMIRIS (ravulizumab): Alexion Pharmaceuticals
Ravulizumab-cwvz, a complement inhibitor, is a humanized monoclonal antibody (mAb) produced in Chinese hamster (CHO) cells. ULTOMIRIS is indicated for the treatment of adult and pediatric patients 1 month of age and older with aHUS to inhibit complement-mediated thrombotic microangiopathy (TMA).

• SOLIRIS (eculizumab): Alexion Pharmaceuticals
Eculizumab, a complement inhibitor, is a recombinant humanized monoclonal IgG2/4κ antibody produced by murine myeloma cell culture and purified by standard bioprocess technology. Eculizumab contains human constant regions from human IgG2 sequences, human IgG4 sequences, and murine complementarity-determining regions grafted onto the human framework light and heavy-chain variable regions. SOLIRIS is indicated for the treatment of patients with aHUS to inhibit complement-mediated thrombotic microangiopathy.

Emerging Atypical Hemolytic Uremic Syndrome Therapies
• Crovalimab (RG6107; SKY59): Hoffmann-La Roche/Chugai Pharmaceutical
Crovalimab (RG6107) is a humanized complement inhibitor C5 monoclonal antibody discovered by Chugai using recycling antibody technology. Blocking the cleavage of C5 to C5a and C5b is expected to inhibit complement activation, which is the cause of several diseases. As the complement system is a key innate immune defense mechanism, it is planned to study the potential of this antibody in a broader range of complement-mediated diseases.

• FABHALTA (iptacopan): Novartis Pharmaceuticals
Iptacopan, also known as LNP023, is a first-in-class, orally-administered, small-molecule, potent, and highly selective factor B (FB) inhibitor, a key serine protease of the alternative pathway of the complement cascade. Currently, iptacopan is in the Phase III development stage. The ongoing Phase III clinical trial is a multicenter, single-arm, open-label trial to evaluate the efficacy and safety of oral, twice-daily LNP023 in adult aHUS patients who are naive to complement inhibitor therapy.

Atypical Hemolytic Uremic Syndrome Treatment Market Landscape
The Atypical Hemolytic Uremic Syndrome treatment market landscape has witnessed significant advancements over the past years, with targeted therapies playing a crucial role in improving outcomes for patients. Among these targeted therapies, the emergence of Atypical Hemolytic Uremic Syndrome has garnered attention in the medical community, presenting both challenges and opportunities in treatment strategies.

To learn more about Atypical Hemolytic Uremic Syndrome treatment guidelines, visit @ Atypical Hemolytic Uremic Syndrome Treatment Market Landscape- https://www.delveinsight.com/sample-request/atypical-hemolytic-uremic-syndrome-ahus-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Atypical Hemolytic Uremic Syndrome Market Outlook
The introduction of complement C5 inhibition into the treatment landscape has significantly improved patient prognosis and QoL. Currently available complement C5 inhibitors across the 7MM are SOLIRIS (eculizumab) and ULTOMIRIS (ravulizumab), both Alexion Pharmaceuticals products. The treatment transition of patients being treated with eculizumab to ravulizumab has been established as a viable treatment strategy, as this would lead to a reduction in the dosing frequency, which would then lead to a significant reduction of economic burden (treatment-related costs of repeated infusions) and improve the overall QoL of patients..

Atypical Hemolytic Uremic Syndrome Drugs Uptake
aHUS is an extremely rare disease characterized by low levels of circulating red blood cells due to their destruction (hemolytic anemia), low platelet count (thrombocytopenia) due to their consumption, and the inability of the kidneys to process waste products from the blood and excrete them into the urine (acute kidney failure), a condition known as uremia. Hemolytic anemia occurs when RBC undergoes hemolysis faster than normal. In aHUS, RBCs can break apart as they squeeze past clots within small blood vessels. If cells are destroyed faster than the body can replace them, it leads to anemia. As a result of clot formation in small blood vessels, patients experience kidney damage and acute kidney failure, leading to end-stage renal disease (ESRD) in about half of all cases.

Major Atypical Hemolytic Uremic Syndrome Companies
Alexion Pharmaceuticals, Omeros Corporation, Novartis Pharmaceuticals, Hoffmann-La Roche, Chugai Pharmaceutical and others.

Learn more about the FDA-approved drugs for Atypical Hemolytic Uremic Syndrome @ Drugs for Atypical Hemolytic Uremic Syndrome Treatment- https://www.delveinsight.com/sample-request/atypical-hemolytic-uremic-syndrome-ahus-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Scope of the Atypical Hemolytic Uremic Syndrome Market Report
• Coverage- 7MM
• Study Period- 2020-2034
• Atypical Hemolytic Uremic Syndrome Companies- Alexion Pharmaceuticals, Omeros Corporation, Novartis Pharmaceuticals, Hoffmann-La Roche, Chugai Pharmaceutical and others.
• Atypical Hemolytic Uremic Syndrome Pipeline Therapies- Eculizumab, Crovalimab, Iptacopan, Ravulizumab, OMS721, and others.
• Atypical Hemolytic Uremic Syndrome Market Dynamics: Atypical Hemolytic Uremic Syndrome Market Drivers and Barriers
• Atypical Hemolytic Uremic Syndrome Market Access and Reimbursement, Unmet Needs and Future Perspectives, Atypical Hemolytic Uremic Syndrome Clinical Trials

Discover more about Atypical Hemolytic Uremic Syndrome Drugs in development @ Atypical Hemolytic Uremic Syndrome Clinical Trials Assessment- https://www.delveinsight.com/sample-request/atypical-hemolytic-uremic-syndrome-ahus-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Table of Content
1. Key Insights
2. Atypical Hemolytic Uremic Syndrome Executive Summary
3. Atypical Hemolytic Uremic Syndrome Competitive Intelligence Analysis
4. Atypical Hemolytic Uremic Syndrome: Market Overview at a Glance
5. Atypical Hemolytic Uremic Syndrome: Disease Background and Overview
6. Patient Journey
7. Atypical Hemolytic Uremic Syndrome Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. Atypical Hemolytic Uremic Syndrome Unmet Needs
10. Key Endpoints of Atypical Hemolytic Uremic Syndrome Treatment
11. Atypical Hemolytic Uremic Syndrome Marketed Products
12. Atypical Hemolytic Uremic Syndrome Emerging Therapies
13. Atypical Hemolytic Uremic Syndrome: Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Atypical Hemolytic Uremic Syndrome Market Outlook
16. Access and Reimbursement Overview of Atypical Hemolytic Uremic Syndrome
17. KOL Views
18. Atypical Hemolytic Uremic Syndrome Market Drivers
19. Atypical Hemolytic Uremic Syndrome Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
23. About DelveInsight

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About Us

DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve.

Contact Us
Yash Bhardwaj
info@delveinsight.com
https://www.delveinsight.com/
India:- +91-9650213330

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