Steroid Refactory Acute Graft-Versus-Host Disease Market Set to Grow Substantially Through 2032, DelveInsight Projects | medac GmbH, AltruBio Inc., MaaT Pharma, Incyte Corporation The Steroid Refactory Acute Graft-Versus-Host Disease

market is expected to surge due to the disease's increasing prevalence and awareness during the forecast period. Furthermore, launching various multiple-stage pipeline products will significantly revolutionize the Steroid Refactory Acute Graft-Versus-Host Disease market dynamics.

DelveInsight's "Steroid Refactory Acute Graft-Versus-Host Disease Market Insights, Epidemiology, and Market Forecast-2032′′ report offers an in-depth understanding of the Steroid Refactory Acute Graft-Versus-Host Disease, historical and forecasted epidemiology as well as the Steroid Refactory Acute Graft-Versus-Host Disease market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

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Some of the key facts of the Steroid Refactory Acute Graft-Versus-Host Disease Market Report:
• The Steroid Refactory Acute Graft-Versus-Host Disease market size is anticipated to grow with a significant CAGR during the study period (2019-2032)
• In May 2025, MaaT Pharma (EURONEXT: MAAT), a clinical-stage biotech company specializing in Microbiome Ecosystem TherapiesTM (MET) to improve cancer patient survival through immune modulation, announced that following the EMA Pediatric Committee's approval of its Pediatric Investigation Plan (PIP), the Data and Safety Monitoring Board (DSMB) has completed its final safety review of the pivotal Phase 3 ARES trial. This single-arm, open-label, multicenter European study evaluates the efficacy and safety of MaaT013 in patients with acute Graft-versus-Host Disease (GI-aGvHD) involving the gastrointestinal tract, who are receiving third-line treatment after being refractory to steroids and either refractory or intolerant to ruxolitinib.
• In December 2024, The FDA has approved remestemcel-L-rknd (Ryoncil) for treating pediatric patients aged two months and older with steroid-refractory acute graft-versus-host disease (GVHD), according to an agency announcement. The approval is supported by results from the multicenter, prospective, single-arm MSB-GVHD001 trial (NCT02336230), which evaluated the allogeneic bone marrow-derived MSC therapy in 54 children with steroid-refractory acute GVHD following allogeneic hematopoietic stem cell transplantation (HSCT).
• In December 2024, The FDA has granted approval to Mesoblast's allogeneic bone marrow-derived mesenchymal stromal cell (MSC) therapy, remestemcel-L, for treating steroid-refractory acute graft-versus-host disease (GvHD) in children aged two months and older.
• The biopsy may help confirm Steroid Refactory Acute Graft-Versus-Host Disease diagnosis, but lacks sensitivity and specificity
• In around 35-50% of patients, aGVHD becomes refractory to systemic steroid therapy
• Key Steroid Refactory Acute Graft-Versus-Host Disease Companies: : MaaT Pharma, medac GmbH, AltruBio Inc., Incyte Corporation, and others
• Key Steroid Refactory Acute Graft-Versus-Host Disease Therapies: MC0518, Neihulizumab, T-Guard, Ruxolitinib, Apraglutide, and others
• The Steroid Refactory Acute Graft-Versus-Host Disease diagnosis is carried through laboratory analysis, imaging, and or endoscopic

Steroid Refactory Acute Graft-Versus-Host Disease Overview
Steroid-Refractory Acute Graft-Versus-Host Disease (SR-aGVHD) is a serious and life-threatening complication that occurs after an allogeneic stem cell or bone marrow transplant. In this condition, the donated immune cells attack the recipient's body tissues. Normally, steroids are the first line of treatment to control this immune response. However, in steroid-refractory cases, patients either do not respond to steroids or their symptoms worsen, making the disease harder to manage. SR-aGVHD often affects organs such as the skin, liver, and gastrointestinal tract and requires alternative therapies to improve survival and quality of life.

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Steroid Refactory Acute Graft-Versus-Host Disease Epidemiology
The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides a detailed analysis of the diagnosed patient pool and future trends.

Steroid Refactory Acute Graft-Versus-Host Disease Epidemiology Segmentation:
The Steroid Refactory Acute Graft-Versus-Host Disease market report proffers epidemiological analysis for the study period 2019-2032 in the 7MM segmented into:
• Total Prevalence of Steroid Refactory Acute Graft-Versus-Host Disease
• Prevalent Cases of Steroid Refactory Acute Graft-Versus-Host Disease by severity
• Gender-specific Prevalence of Steroid Refactory Acute Graft-Versus-Host Disease
• Diagnosed Cases of Episodic and Chronic Steroid Refactory Acute Graft-Versus-Host Disease

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Steroid Refactory Acute Graft-Versus-Host Disease Market
The dynamics of the Steroid Refactory Acute Graft-Versus-Host Disease market are anticipated to change in the coming years owing to the expected launch of emerging therapies such as Itacitinib, MaaT013, and others during the forecasted period 2019-2032.

Steroid Refactory Acute Graft-Versus-Host Disease Therapies and Emerging Therapies
• MC0518: MaaT Pharma
• Neihulizumab: medac GmbH
• T-Guard: AltruBio Inc
• Ruxolitinib: Incyte Corporation

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Steroid Refactory Acute Graft-Versus-Host Disease Market Drivers
• Rising Incidence of Hematopoietic Stem Cell Transplantation (HSCT)
• High Unmet Medical Need
• Regulatory Support & Designations
• Ongoing Clinical Trials & Emerging Therapies
• Increased Awareness & Diagnosis

Steroid Refactory Acute Graft-Versus-Host Disease Market Barriers
• Complex Pathophysiology
• High Cost of Treatment
• Limited Patient Pool
• Adverse Effects of Therapies
• Delayed Diagnosis and Referral

Scope of the Steroid Refactory Acute Graft-Versus-Host Disease Market Report
• Study Period: 2019-2032
• Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]
• Key Steroid Refactory Acute Graft-Versus-Host Disease Companies: MaaT Pharma, medac GmbH, AltruBio Inc., Incyte Corporation, and others
• Key Steroid Refactory Acute Graft-Versus-Host Disease Therapies: MC0518, Neihulizumab, T-Guard, Ruxolitinib, Apraglutide, and others
• Therapeutic Assessment: Steroid Refactory Acute Graft-Versus-Host Disease current marketed and Steroid Refactory Acute Graft-Versus-Host Disease emerging therapies
• Migraine Market Dynamics: Steroid Refactory Acute Graft-Versus-Host Disease market drivers and barriers
• Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
• Unmet Needs, KOL's views, Analyst's views, Steroid Refactory Acute Graft-Versus-Host Disease Market Access and Reimbursement

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Table of Contents
1. Steroid Refactory Acute Graft-Versus-Host Disease Market Report Introduction
2. Executive Summary for Steroid Refactory Acute Graft-Versus-Host Disease
3. SWOT analysis of Steroid Refactory Acute Graft-Versus-Host Disease
4. Steroid Refactory Acute Graft-Versus-Host Disease Patient Share (%) Overview at a Glance
5. Steroid Refactory Acute Graft-Versus-Host Disease Market Overview at a Glance
6. Steroid Refactory Acute Graft-Versus-Host Disease Disease Background and Overview
7. Steroid Refactory Acute Graft-Versus-Host Disease Epidemiology and Patient Population
8. Country-Specific Patient Population of Steroid Refactory Acute Graft-Versus-Host Disease
9. Steroid Refactory Acute Graft-Versus-Host Disease Current Treatment and Medical Practices
10. Steroid Refactory Acute Graft-Versus-Host Disease Unmet Needs
11. Steroid Refactory Acute Graft-Versus-Host Disease Emerging Therapies
12. Steroid Refactory Acute Graft-Versus-Host Disease Market Outlook
13. Country-Wise Steroid Refactory Acute Graft-Versus-Host Disease Market Analysis (2019-2032)
14. Steroid Refactory Acute Graft-Versus-Host Disease Market Access and Reimbursement of Therapies
15. Steroid Refactory Acute Graft-Versus-Host Disease Market drivers
16. Steroid Refactory Acute Graft-Versus-Host Disease Market barriers
17. Steroid Refactory Acute Graft-Versus-Host Disease Appendix
18. Steroid Refactory Acute Graft-Versus-Host Disease Report Methodology
19. DelveInsight Capabilities
20. Disclaimer
21. About DelveInsight

Related Reports:

Steroid Refactory Acute Graft-Versus-Host Disease Pipeline https://www.delveinsight.com/report-store/steroid-refractory-acute-graft-versus-host-disease-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=gpr
"Steroid Refactory Acute Graft-Versus-Host Disease Pipeline Insight, 2025" report by DelveInsight outlines comprehensive insights of present clinical development scenarios and growth prospects across the Steroid Refactory Acute Graft-Versus-Host Disease market. A detailed picture of the Steroid Refactory Acute Graft-Versus-Host Disease pipeline landscape is provided, which includes the disease overview and Steroid Refactory Acute Graft-Versus-Host Disease treatment guidelines.

Steroid Refactory Acute Graft-Versus-Host Disease Epidemiology https://www.delveinsight.com/report-store/steroid-refactory-acute-graft-versus-host-disease-gvhd-epidemiology-forecast?utm_source=openpr&utm_medium=pressrelease&utm_campaign=gpr
DelveInsight's 'Steroid Refactory Acute Graft-Versus-Host Disease Epidemiology Forecast to 2032' report delivers an in-depth understanding of the disease, historical and forecasted Steroid Refactory Acute Graft-Versus-Host Disease epidemiology in the 7MM, i.e., the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan.

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