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Bone Grafts and Substitutes Market to Reach $4.4 Billion by 2033, growing at a CAGR of 4.4% | Johnson & Johnson, Orthofix Holdings, Inc., Zimmer Biomet Holdings

05-09-2025 11:03 AM CET | Business, Economy, Finances, Banking & Insurance

Press release from: Allied Market Research

/ PR Agency: Allied Market Research
Bone Grafts and Substitutes Market to Reach $4.4 Billion by 2033,

Bone substitutes are synthetic materials that are designed to mimic the structure and function of natural bone. They are made from a variety of materials such as ceramics, metals, and polymers. These substitutes can be used alone or in combination with bone grafts to help promote bone growth and healing. They are used in a similar range of conditions as bone grafts such as spinal fusion, fracture repair and bone cancer treatment.

According to the report, the "bone grafts and substitutes market" was valued at $2.8 billion in 2023, and is estimated to reach $4.4 billion by 2033, growing at a CAGR of 4.4% from 2024 to 2033.

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Prime determinants of growth

Furthermore, new materials and methods for bone grafting have been developed as a result of medical technology breakthroughs, improving the safety and efficacy of surgery. Moreover, the need for orthopedic operations is being driven by the world's aging population, which is further boosting market expansion. Additionally, the market for bone substitutes and grafts is witnessing growth due to rise in awareness of the significance of bone health and the availability of numerous treatment alternatives.

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The major factors driving the growth of the bone grafts and substitutes market are increase in number of road accidents & joint disorders, increase in demand of dental bone grafts and rise in geriatric population. Bone grafts and substitutes are often used to help heal bone fractures and other injuries caused by accidents. In addition, in many cases, they can be used to replace or repair damaged bone tissue, helping to restore normal function and mobility. Further, bone grafts and substitutes may be required in cases where the bone has been severely damaged or lost due to the accident. In these cases, bone grafts or substitutes can be used to help regenerate new bone tissue, which can help restore function and mobility of the affected area.

Regional Outlook

By region, North America held the largest market share in terms of revenue in 2023, the global bone grafts and substitutes market revenue, and is expected to dominate the market during the forecast period. This is attributed to its advanced technology infrastructure, strong demand & availability of bone grafts, supportive regulatory environment, and collaborative ecosystem fostering innovation and growth in the bone grafts and substitutes market. However, the Asia-Pacific region is expected to witness rapid industrialization in countries such as China and India. This has led to the establishment and expansion of manufacturing facilities, including advancements and accessibility of such products along with surge in the geriatric population are expected to drive the market growth during the forecast period.

Key Players:

Arthrex, Inc.
Johnson & Johnson
Medtronic plc
NuVasive, Inc.
Stryker Corporation
Zimmer Biomet Holdings, Inc.
Baxter International Inc.
Xtant Medical Holdings, Inc.
Integra LifeSciences
Orthofix Holdings Inc.

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Allied Market Research (AMR) is a full-service market research and business consulting wing of Allied Analytics LLP based in Wilmington, Delaware. Allied Market Research provides end-to-end solutions along with information, education, advocacy, and networking resources to SMEs and early-stage start-ups to bring excellence to their processes. In addition, we offer a nurturing environment required to develop and grow businesses, including business planning; virtual support; market intelligence; acquiring resources; and getting direct access to finance, suppliers, and other experts to boost the growth of businesses and entrepreneurs.

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