Leber's Hereditary Optic Neuropathy Treatment Market Size in 7MM is expected to grow at a decent CAGR by 2032, estimates DelveInsight | Stealth BioTherapeutics Inc., Santhera Pharmaceuticals, GenSight Biologics, Amgen

DelveInsight's "Leber's Hereditary Optic Neuropathy Market Insights, Epidemiology, and Market Forecast- 2032" report delivers an in-depth understanding of the Leber's Hereditary Optic Neuropathy, historical and forecasted epidemiology as well as the Leber's Hereditary Optic Neuropathy market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

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Key Takeaways from the Leber's Hereditary Optic Neuropathy Market Report
• According to Shemesh et. al. (2022), Leber's hereditary optic neuropathy (LHON) is estimated to be the most frequent mitochondrial disease with a prevalence ranging from 1 in 27,000 in North East England to 1 in 45,000 in a meta-analysis of reports in the European population. It has a strong male preponderance (80% to 90%), and the usual age at onset is between 15 to 35 years.
• As per the NORD (2019), the prevalence of visual loss from LHON is approximately 1:50,000 people. Many carriers never suffer significant visual loss; males are about four to five times more likely than females to lose vision and be affected.
• As per Man et. al. (2016), LHON is characterized by a marked gender bias, with males more likely to become affected than females.
• According to a national epidemiological survey on LHON conducted by Takano et. al. (2022) in Japan, the number of newly diagnosed patients with LHON in 2019 was estimated to be 69, and the total number of LHON patients in Japan was estimated to be 2400, with a prevalence similar to other countries.
• The increase in Leber's Hereditary Optic Neuropathy Market Size is a direct consequence of the increasing patient population and anticipated launch of emerging therapies in the 7MM.
• As per DelveInsight analysis, the Leber's Hereditary Optic Neuropathy Market is anticipated to witness growth at a considerable CAGR.
• The leading Leber's Hereditary Optic Neuropathy Companies such as Stealth BioTherapeutics Inc., Santhera Pharmaceuticals,GenSight Biologics, Amgen and others.
• Promising Leber's Hereditary Optic Neuropathy Pipeline Therapies such as GS010, Cysteamine Bitartrate, Idebenone,elamipretide (MTP-131) and others.

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Leber's Hereditary Optic Neuropathy Epidemiology Segmentation in the 7MM
The epidemiology section of Leber's Hereditary Optic Neuropathy offers insights into both historical and current patient populations, as well as forecasted trends across seven major countries. This section aids in understanding the factors behind present and projected trends through analysis of various studies and input from key opinion leaders. Additionally, this portion of the market report provides information on the diagnosed patient pool, trends, and underlying assumptions.

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Leber's Hereditary Optic Neuropathy Emerging Drugs
• GS010 (lenadogene nolparvovec): GenSight
GS010 is a gene therapy-based treatment administered through a single injection into the eye, specifically targeting LHON. This therapy utilizes GenSight's proprietary Mitochondrial Targeting Sequence (MTS) technology platform, which facilitates the transportation of missing mitochondrial proteins into the mitochondrion, ultimately leading to the restoration of mitochondrial function.

• Elamipretide: Stealth Biotherapeutics
Elamipretide, developed by Stealth Biotherapeutics, is a peptide compound with the unique ability to easily enter cell membranes and specifically target the inner mitochondrial membrane. Once inside the mitochondria, it forms a reversible bond with cardiolipin. This association between elamipretide and cardiolipin has been demonstrated to restore the normal structure of the inner mitochondrial membrane, leading to an improvement in mitochondrial function.

Leber's Hereditary Optic Neuropathy Drugs Market
The Leber's Hereditary Optic Neuropathy Drugs Market is expected to witness substantial growth in the coming years as more targeted therapies receive regulatory approval and enter clinical practice. Additionally, ongoing research efforts aimed at better understanding the molecular mechanisms underlying Leber's Hereditary Optic Neuropathy signaling in Leber's Hereditary Optic Neuropathy are likely to uncover new therapeutic targets and further expand treatment options for patients.

Leber's Hereditary Optic Neuropathy Treatment Market Landscape
The LHON treatment market landscape has witnessed significant advancements over the past years, with targeted therapies playing a crucial role in improving outcomes for patients. Among these targeted therapies, the emergence of Leber's Hereditary Optic Neuropathy has garnered attention in the medical community, presenting both challenges and opportunities in treatment strategies.

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LHON Market Outlook
The report's outlook on the LHON market aids in developing a comprehensive understanding of historical, current, and projected trends. This is achieved by examining the influence of existing Leber's Hereditary Optic Neuropathy clinical trials, drugs, unmet needs, as well as drivers, barriers, and the demand for advanced technology. This section provides detailed insights into the trends of each marketed Leber's Hereditary Optic Neuropathy drug and late-stage pipeline therapy.

Leber's Hereditary Optic Neuropathy Drugs Uptake
The drug chapter of the Leber's Hereditary Optic Neuropathy report provides a comprehensive analysis of both marketed drugs and late-stage pipeline drugs for this condition. It delves into the details of Leber's Hereditary Optic Neuropathy clinical trials, pharmacological actions, agreements, collaborations, approvals, patents, and advantages, and disadvantages of each drug, as well as the latest news and press releases related to Leber's Hereditary Optic Neuropathy.

Major Leber's Hereditary Optic Neuropathy Companies
Stealth BioTherapeutics Inc., Santhera Pharmaceuticals, GenSight Biologics, Amgen and others.

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Scope of the Leber's Hereditary Optic Neuropathy Market Report
• Coverage- 7MM
• Study Period- 2019-2032
• Leber's Hereditary Optic Neuropathy Companies- and others.
• Leber's Hereditary Optic Neuropathy Pipeline Therapies- GS010, Cysteamine Bitartrate, Idebenone,elamipretide (MTP-131) and others.
• Leber's Hereditary Optic Neuropathy Market Dynamics: LHON Market Drivers and Barriers
• Leber's Hereditary Optic Neuropathy Market Access and Reimbursement, Unmet Needs and Future Perspectives, Leber's Hereditary Optic Neuropathy Clinical Trials

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Table of Content
1. Key Insights
2. Leber's Hereditary Optic Neuropathy Executive Summary
3. Leber's Hereditary Optic Neuropathy Competitive Intelligence Analysis
4. Leber's Hereditary Optic Neuropathy: Market Overview at a Glance
5. Leber's Hereditary Optic Neuropathy: Disease Background and Overview
6. Patient Journey
7. Leber's Hereditary Optic Neuropathy Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. Leber's Hereditary Optic Neuropathy Unmet Needs
10. Key Endpoints of Leber's Hereditary Optic Neuropathy Treatment
11. Leber's Hereditary Optic Neuropathy Marketed Products
12. Leber's Hereditary Optic Neuropathy Emerging Therapies
13. Leber's Hereditary Optic Neuropathy: Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Leber's Hereditary Optic Neuropathy Market Outlook
16. Access and Reimbursement Overview of Leber's Hereditary Optic Neuropathy
17. KOL Views
18. Leber's Hereditary Optic Neuropathy Market Drivers
19. Leber's Hereditary Optic Neuropathy Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
23. About DelveInsight

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