Press release
Poly(ADP-Ribose) Polymerase (PARP) Inhibitors Market Size Projected To Reach $2.52 Billion By 2034 With A Cagr Of 6%
Poly(ADP-Ribose) Polymerase (PARP) Inhibitors
What Is the Projected Growth of the Poly(ADP-Ribose) Polymerase (PARP) Inhibitors Market?
The market size for poly(ADP-ribose) polymerase (PARP) inhibitors has seen a swift expansion in the past few years. It is projected to escalate from $6.53 billion in 2024 to $7.56 billion in 2025, with a compound annual growth rate (CAGR) of 15.7%. The substantial growth during the historic period can be credited to a rise in cancer cases, advancement in genetic testing, successful clinical trials, expansion in insurance coverage, and progression in cancer-related research.
In the forthcoming years, the market for poly(ADP-ribose) polymerase (PARP) inhibitors is predicted to witness rapid expansion, escalating to $13.45 billion by 2029 with a compound annual growth rate (CAGR) of 15.5%. This predicted growth is primarily due to increasing drug production and supply, the prevalence of BRCA-mutated cancers, the rising incidence of breast cancer, the proliferation of monoclonal antibodies usage, and growing healthcare spending. The forecast period is expected to witness significant trends such as advancements in biomarker research, the rise of combination therapies, the use of artificial intelligence in drug development, progress in biomarker-led therapy, and the introduction of next-generation PARP inhibitors.
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What Are the Different Poly(ADP-Ribose) Polymerase (PARP) Inhibitors Market Segments?
The poly(ADP-ribose) polymerase (PARP) inhibitors market covered in this report is segmented -
1) By Type: Olaparib, Rucaparib, Niraparib, Talazoparib, Other Types
2) By Indication: Ovarian Cancer, Breast Cancer, Prostate Cancer, Pancreatic Cancer
3) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies
4) By End-User: Hospitals, Specialty Clinics, Research Institutions, Other End-Users
Subsegments:
1) By Olaparib: BRCA-Mutated Cancers, HRD-Positive Cancers, Maintenance Therapy
2) By Rucaparib: Ovarian Cancer, Prostate Cancer, Pancreatic Cancer
3) By Niraparib: First-Line Treatment, Recurrent Cancer Treatment, Late-Stage Cancer
4) By Talazoparib: Breast Cancer, Germline BRCA-Mutated Tumors, Neoadjuvant Or Adjuvant Therapy
5) By Other Types: Emerging PARP Inhibitors, Investigational Therapies, Novel Combinations
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What Are the Primary Drivers Shaping the Poly(ADP-Ribose) Polymerase (PARP) Inhibitors Market?
The increasing occurrence of breast cancer is anticipated to stimulate the expansion of the poly(ADP-ribose) polymerase (PARP) inhibitors market. Breast cancer is a disease characterized by uncontrolled growth of cells in the breast, leading to the formation of a harmful tumor that can metastasize to different body parts. The escalating incidence of this cancer is largely due to aging populations, shifts in lifestyle, hereditary factors, hormonal imbalances, obesity, alcohol intake, and elevated exposure to hazardous environmental factors. PARP inhibitors, which obstruct the PARP enzyme's DNA damage repair function in cancer cells, are particularly effective for tumors carrying BRCA1 or BRCA2 mutations, thus aiding breast cancer patients by causing cell death. For example, it was reported in January 2025 by the US-based National Breast Cancer Foundation that one out of every eight women in the United States will be diagnosed with breast cancer in their lifetime. In 2024, a total of 310,720 women and 2,800 men were identified to have invasive breast cancer. Consequently, this increasing prevalence of breast cancer is fueling the growth of the poly(ADP-ribose) polymerase (PARP) inhibitors market.
Which Companies Are Leading in the Poly(ADP-Ribose) Polymerase (PARP) Inhibitors Market?
Major companies operating in the poly(ADP-ribose) polymerase (PARP) inhibitors market are Pfizer Inc., Johnson & Johnson Services Inc., AbbVie Inc., Merck & Co. Inc., Bayer AG, AstraZeneca plc, Bristol-Myers Squibb Company, GSK plc, Takeda Pharmaceutical Company Limited, Boehringer Ingelheim, Vertex Pharmaceuticals Inc., Jiangsu Hengrui Pharmaceuticals Co. Ltd., BeiGene LTD, Karyopharm Therapeutics Inc., Clovis Oncology Inc., Repare Therapeutics Inc., Ribon Therapeutics, Artios Pharma, IMPACT Therapeutics Inc., BiPar Sciences Inc., Allarity Therapeutics Inc.
What Are the Major Trends Shaping the Poly(ADP-Ribose) Polymerase (PARP) Inhibitors Market?
Top-tier corporations in the poly(ADP-ribose) polymerase (PARP) inhibitors market are focusing on the innovation of superior therapies for cancer, such as anticancer medicines, aimed at addressing the unique genetic variations common in certain types of cancer. Treatments such as anticancer medicines combat cancer by stifling the growth of cancer cells, halting their proliferation, or annihilating them. These treatments utilize different methods, such as disrupting cell multiplication, obstructing unique proteins crucial for tumor proliferation, or bolstering the immune system to battle cancer. For example, in March 2024, Zydus Lifesciences Limited, a pharmaceutical company based in India, unveiled IBYRA, an economical, generic variant of the PARP inhibitor olaparib, within the Indian market. This drug is an efficient treatment solution for individuals with HRD-positive and BRCA-positive cancers, notably cutting treatment expenses compared to the original drug.
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What Are the Top Revenue-Generating Geographies in the Poly(ADP-Ribose) Polymerase (PARP) Inhibitors Market?
North America was the largest region in the poly(ADP-ribose) polymerase (PARP) inhibitors market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the poly(ADP-ribose) polymerase (PARP) inhibitors market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
Frequently Asked Questions:
1. What Is the Market Size and Growth Rate of the Poly(ADP-Ribose) Polymerase (PARP) Inhibitors Market?
2. What is the CAGR expected in the Poly(ADP-Ribose) Polymerase (PARP) Inhibitors Market?
3. What Are the Key Innovations Transforming the Poly(ADP-Ribose) Polymerase (PARP) Inhibitors Industry?
4. Which Region Is Leading the Poly(ADP-Ribose) Polymerase (PARP) Inhibitors Market?
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