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Hereditary Angioedema Market Forecast 2025-2034: Comprehensive Analysis And Growth Opportunities
The Hereditary Angioedema Market Report by The Business Research Company delivers a detailed market assessment, covering size projections from 2025 to 2034. This report explores crucial market trends, major drivers and market segmentation by [key segment categories].What Is the Projected Growth of the Hereditary Angioedema Market?
Recent years have seen a solid increase in the hereditary angioedema market size. It is projected that this market will expand from $2.62 billion in 2024 to $2.84 billion in 2025, reflecting a compound annual growth rate (CAGR) of 8.7%. This significant growth throughout the historic period can be ascribed to an increased incidence of hereditary angioedema, heightened investment in research and development, a surge in drug approvals, an escalation in product approval, alongside a rising disposable income.
Anticipated robust expansion is predicted for the hereditary angioedema market in the forthcoming years. By 2029, it is projected to reach $3.93 billion, with a compound annual growth rate (CAGR) of 8.4%. This surge during the predicted period is due to factors such as the increased occurrence of uncommon diseases, rising healthcare expenditure, amplified assistance from non-profit entities, heightened awareness regarding hereditary angioedema, and growing consciousness early diagnosis. In the same forecast period, key trends encompass technological progress, the inception of innovative therapies, the introduction of new pharmaceuticals, state-of-the-art diagnostic instruments, and improvements in genetic testings.
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What Are the Different Hereditary Angioedema Market Segments?
The hereditary angioedema market covered in this report is segmented -
1) By Type: Hereditary Angioedema Type I, Hereditary Angioedema Type II
2) By Treatment Type: Prophylaxis, On-demand
3) By Drug Class: C-1 Esterase Inhibitors, Bradykynin Receptor Antagonist, Kallikrein Inhibitors, Other Drug Classes
4) By Route Of Administration: Subcutaneous, Intravenous, Oral
5) By Distribution channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies
Subsegments:
1) By Hereditary Angioedema Type I: C1-Inhibitor Deficiency, Low C1-Inhibitor Levels, Reduced C1-Inhibitor Function
2) By Hereditary Angioedema Type II: Normal C1-Inhibitor Levels, Dysfunctional C1-Inhibitor, Genetic Mutations In SERPING1 Gene
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What Are the Primary Drivers Shaping the Hereditary Angioedema Market?
The hereditary angioedema market is anticipated to grow due to the rising incidence of rare or orphan diseases, categorized as such due to their affliction of only a small proportion of the population. Numerous causes, including advances in medical research, fluctuations in population demographics, and environmental influences, contribute to the escalation of these rare diseases. Hereditary angioedema (HAE) is a noteworthy rare disease that causes serious swelling episodes, necessitating the development of exclusive treatments and enhanced awareness due to its life-threatening potential. Its infrequency and genetic origin necessitate early detection and tailored treatments for effective control and improved patient outcomes. The Rare Disease Advisor, a US-based virtual resource company for healthcare professionals, reported in June 2022 that hereditary angioedema (HAE) affects roughly one in 50,000 individuals, with disorder prevalence estimates varying from one in 10,000 to one in 150,000. Approximately 15,000-30,000 emergency room visits annually in the United States are due to HAE episodes. Consequently, the escalating prevalence of rare diseases is fueling the growth of the hereditary angioedema market.
Which Companies Are Leading in the Hereditary Angioedema Market?
Major companies operating in the hereditary angioedema market are Intellia Therapeutics Inc., Sanofi S.A., Takeda Pharmaceutical Company Limited, Otsuka Pharmaceutical Co. Ltd., CSL Limited, Cipla Limited, BioMarin Pharmaceutical Inc., Ionis Pharmaceuticals Inc., BioCryst Pharmaceuticals Inc., Arrowhead Pharmaceuticals Inc., Spark Therapeutics Inc., Pharming Group N.V., Pharvaris N.V., Astria Therapeutics Inc., CENTOGENE N.V., KalVista Pharmaceuticals Inc., ADARx Pharmaceuticals Inc., Adverum Biotechnologies Inc., Attune Pharmaceuticals Inc., Lev Pharmaceuticals Inc.
What Are the Major Trends Shaping the Hereditary Angioedema Market?
Prominent organizations involved in the hereditary angioedema market are focusing on the creation of pioneering products like oral plasma kallikrein inhibitors that offer more practical and potent on-demand treatment options for sufferers. These inhibitors are medications that obstruct plasma kallikrein to impede the overproduction of bradykinin primarily for hereditary angioedema treatment. For example, KalVista Pharmaceuticals, Inc., an American pharmaceutical firm, declared in September 2024 that the FDA has given its approval to its new drug application (NDA) for a drug called sebetralstat. Developed as an oral plasma kallikrein inhibitor, it is designed for the as-needed treatment of hereditary angioedema (HAE) attacks in adults and children 12 years and older. By targeting and inhibiting the plasma kallikrein activity, sebetralstat introduces a novel treatment strategy. The NDA's acceptance signals a significant leap towards possible approval and market introduction.
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What Are the Top Revenue-Generating Geographies in the Hereditary Angioedema Market?
North America was the largest region in the hereditary angioedema market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the hereditary angioedema market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
Frequently Asked Questions:
1. What Is the Market Size and Growth Rate of the Hereditary Angioedema Market?
2. What is the CAGR expected in the Hereditary Angioedema Market?
3. What Are the Key Innovations Transforming the Hereditary Angioedema Industry?
4. Which Region Is Leading the Hereditary Angioedema Market?
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