Laboratory Gas Generators Market to Exceed USD 1.27 Billion by 2031, Driven by Rising Automation, Safety Regulations, and Hydrogen Demand - Exclusive Report

Laboratory gas generators provide on‐demand, high‐purity gases-hydrogen, nitrogen, oxygen, zero air, purge gas-to analytical instruments such as gas chromatographs, LC‐MS systems, ion mobility spectrometers, and clean‐dry gas devices. Eliminating the hazards and logistical burdens of high‐pressure cylinders, these fully automated systems have become indispensable across pharmaceutical, chemical, food & beverage, environmental, and electronics industries. Valued at US$ 449.3 Mn in 2021, the global market is forecast to grow at an 11.0 % CAGR from 2022 to 2031, surpassing US$ 1.27 Bn by 2031.

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Analysts' Viewpoint

Experts note that the rapid shift toward laboratory automation, combined with mounting safety and environmental regulations, is accelerating the adoption of gas generators. Helium shortages have driven laboratories to hydrogen‐based solutions, while rising R&D investments in life sciences and food safety testing further bolster demand. Strategic acquisitions and joint ventures among leading suppliers are expanding geographic reach and product portfolios, positioning the market for robust, long‐term expansion.

Market Drivers

Surge in Laboratory Automation

Fully automated generators streamline analytical workflows and reduce operator intervention.

Integration with instrument control systems enhances uptime and data consistency.

Helium Shortages Prompt Hydrogen Adoption

Global helium supply constraints have increased costs and supply risks.

Hydrogen generators, using electrolysis or steam reforming, offer a reliable alternative.

Stringent Safety Regulations and Cylinder Replacement

Regulations on high‐pressure gas handling are tightening in North America and Europe.

On‐site generators eliminate cylinder transport, storage, and handling hazards.

Growth in Analytical R&D

Expansion of pharmaceutical and biotech research drives demand for ultra‐pure gases.

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Market Segmentation

By Product:

Hydrogen Gas Generators - Leading segment, driven by helium substitution and regulatory compliance.

Nitrogen Gas Generators - Widely used for GC carrier and purge gases.

Oxygen Gas Generators - Employed in environmental chambers and combustion analysis.

Zero Air Generators - Essential for flame ionization detectors and calibration.

Purge Gas Generators - Supporting GC and spectroscopic applications.

Others - Specialty gases for niche analytical needs.

By Application:

Gas Chromatography - Largest share, critical for separation and quantification of volatile compounds.

Liquid Chromatography‐Mass Spectrometry (LC‐MS) - Growing adoption in drug discovery and proteomics.

Gas Analyzers - Used in environmental and industrial process monitoring.

Spectroscopy - Including FTIR and UV‐Vis requiring clean, dry gases.

Others - Ion mobility spectrometry, clean‐dry gas devices.

By End‐User:

Pharmaceutical & Biotechnology Companies - Dominant segment, requiring consistent gas purity for R&D and manufacturing.

Chem/Petrochemical Companies - Utilize generators for process analysis and quality control.

Environmental Companies - Rely on generators for air and water quality testing.

Food & Beverage Companies - Employ chromatography for safety and quality assurance.

Others - Academic and research institutions.

Regional and Country Insights

North America (≈ 40 % share in 2021): Led by the U.S., where expanding biotechnology centers (e.g., Eli Lilly's San Diego facility) and stringent safety standards drive on‐site gas generation.

Europe: Steady growth supported by regulatory compliance and established analytical infrastructure in Germany, the U.K., and France.

Asia Pacific: Fastest‐growing region, fueled by rising R&D investments, government research initiatives, and expanding pharmaceutical and food testing industries in China, India, and Japan.

Latin America & MEA: Emerging adoption, with focus on infrastructure development and partnerships to improve laboratory capabilities.

Competitive Landscape

The market is moderately consolidated, with leading players focusing on R&D, strategic alliances, and M&A to enhance their portfolios and global footprint. Key developments include:

Parker Hannifin Corp. - Expanded hydrogen generator lineup for high‐purity applications.

Peak Scientific Instruments Ltd. - Partnered with SCIEX to launch bench solutions for the SCIEX 7500 LC‐MS system.

Angstrom Advanced, Inc.; PerkinElmer, Inc.; Nel ASA; Erre Due s.p.a.; Nitrogenium; F‐DGSi; Airgas, Inc.

Key Developments

July 2021: Scientific Laboratory Supplies launched SLS Lab Pro gas and liquid nitrogen generators in the U.K. and Ireland, eliminating cylinder logistics.

August 2020: Peak Scientific introduced nitrogen generators and bench solutions tailored for the SCIEX 7500 LC‐MS platform.

January 2020: PeakGas unveiled the Genius XE SCI 2, MS Bench (G) SCI 2, MS Bench SCI 2, and i‐Flow O2 oxygen gas generators.

Future Outlook

Over the forecast period, the market is expected to benefit from:

Integration of IoT and remote monitoring for predictive maintenance.

Expansion of mobile and modular gas generation units for field applications.

Continued consolidation through acquisitions to access new geographies.

Growing demand in emerging markets driven by research funding and infrastructure development.

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FAQs

What are the primary benefits of laboratory gas generators?
They provide on‐demand, high‐purity gases, reduce cylinder handling risks, and lower total cost of ownership.

Which product segment leads the market?
Hydrogen gas generators, due to helium shortages and regulatory drivers.

Why is gas chromatography the largest application?
It requires continuous, ultra‐pure carrier gases for sensitive separation of compounds at low concentrations.

Which region dominates the market?
North America, led by the U.S., with ~40 % share driven by advanced biotech infrastructure and safety regulations.

Who are the key market players?
Parker Hannifin, Peak Scientific, PerkinElmer, Angstrom Advanced, Nel ASA, Erre Due, Nitrogenium, F‐DGSi, Airgas.

Driven by the shift toward automation, stringent safety norms, helium supply challenges, and robust R&D activities, the market is poised for dynamic expansion and technological innovation.

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