Arrowhead and Sarepta Forge $11.38 Billion Partnership to Advance Neuromuscular Therapies"

► Global Gene Therapy Market Poised for Robust Growth

The global gene therapy market is experiencing significant expansion, driven by advancements in genetic research and increasing prevalence of genetic disorders. According to Maximize Market Research, the market was valued at USD 10.03 billion in 2024 and is projected to reach USD 32.89 billion by 2032, growing at a compound annual growth rate (CAGR) of 16% during the forecast period.

► Competitive Landscape and Regional Demand

The gene therapy market features a dynamic competitive landscape with key players such as Novartis AG, Gilead Sciences, Biogen, Sarepta Therapeutics, Amgen Inc., and Bluebird Bio focusing on innovative therapies and strategic partnerships to strengthen their market positions. Notably, North America holds the largest market share, attributed to advanced healthcare infrastructure and substantial investments in research and development.

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► United States: Growth and Consolidation in Gene Therapy

The United States is witnessing significant growth in the gene therapy sector, driven by technological innovations and strategic acquisitions. A notable development includes Bluebird Bio's agreement to be acquired by private-equity firms Carlyle Group and SK Capital Partners in a deal worth up to $96 million. This acquisition aims to provide Bluebird with the necessary capital to advance its gene therapies for various diseases.

► Asia-Pacific: Opportunities and Trends in Gene Therapy

The Asia-Pacific region presents substantial opportunities for the gene therapy market, fueled by increasing investments in biotechnology and a growing patient population. However, regulatory challenges have influenced market dynamics. For instance, WuXi AppTec announced the sale of its cell and gene therapy manufacturing unit, WuXi Advanced Therapies, to U.S. private equity firm Altaris LLC. This decision was influenced by U.S. legislative restrictions targeting Chinese firms over national security concerns.

► Europe: Trends and Updation in Gene Therapy

Europe's gene therapy market is evolving with a focus on strategic acquisitions and regulatory developments. AstraZeneca acquired Belgian biotech company EsoBiotec for up to $1 billion, aiming to transform cell therapy treatments for cancer and autoimmune diseases. This acquisition reflects AstraZeneca's commitment to expanding its cell therapy portfolio and making treatments more accessible.

Middle East and Africa: Emerging Opportunities in Gene Therapy

The Middle East and Africa are experiencing emerging opportunities in the gene therapy market, driven by increasing healthcare investments and a rising prevalence of genetic disorders. The market in this region was valued at USD 0.47 billion in 2024 and is anticipated to grow at a CAGR of 29.15%, reaching USD 4.73 billion by 2033.

Recent Mergers and Acquisitions

The gene therapy industry has witnessed notable mergers and acquisitions aimed at consolidating market positions and expanding technological capabilities. In addition to the previously mentioned deals, Arrowhead Pharmaceuticals entered a significant licensing agreement with Sarepta Therapeutics worth up to $11.38 billion over the next five years. This partnership aims to advance therapies targeting neuromuscular diseases and other conditions.

Key Recent Developments

Recent developments in the gene therapy market include regulatory approvals and clinical advancements. The U.S. FDA expanded approval of Sarepta Therapeutics' gene therapy, Elevidys, to include all patients aged four and older with Duchenne muscular dystrophy (DMD). This one-time treatment targets a genetic mutation to slow the progression of DMD, offering new hope to patients and families.

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♦ Breaking Down the Gene Therapy Market: Key Segments Shaping the Industry

► by Delivery Method

In Vivo
Ex Vivo

► by Vector Type

Viral Vectors
Non-Viral Vectors

Depending on the type, viruses that have been modified to transfer therapeutic genes to particular cells are used to create viral vectors. Retroviruses, lentiviruses, adenoviruses, and adeno-associated viruses (AAVs) are common forms of viral vectors. Viral vectors are currently the most popular in the gene therapy industry because of their strong ability to efficiently transfer genes to both dividing and non-dividing cells. AAVs (adeno-associated viruses) have become increasingly popular because of their excellent safety record and ability to provide lasting gene expression. Despite their benefits, viral vectors trigger immune reactions, have restricted cargo space, and present dangers like insertional mutagenesis.

► by Therapeutic Area

Oncology
Neurological Disorders
Cardiovascular Diseases
Others

► by Route of Administration

Intravenous
Others

► by End User

Hospitals and Clinics
Academic and Research Institutes
Biotechnology and Pharmaceutical Companies
Others

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♦ Meet the Industry Leaders Revolutionizing the Gene Therapy Market

1. Organogenesis
2. JCR Pharmaceuticals
3. Japan Tissue Engineering
4. AVITA Medical
5. CHIESI Farmaceutici
6. Stempeutics Research
7. Biosolution
8. MolMed
9. APAC Biotech
10. Gilead Sciences
11. Medipost
12. JW CreaGene
13. Vericel
14. Takeda Pharmaceutical Company
15. Novartis AG
16. Osiris Therapeutics
17. AnGes
18. Tego Sciences
19. Dendreon
20. CollPlant

♦ Uncover Key Insights Answering the Biggest Questions in the Gene Therapy Market

What is Gene Therapy?
What is the growth rate of theGene Therapy Market?
Which are the factors expected to drive the Gene Therapymarket growth?
What is the CAGR at which the Gene Therapy market will grow during the forecast period?
What are the different segments of the Gene Therapy Market?
Which is the fastest growing region in the Gene Therapy market?
What growth strategies are the players considering to increase their presence in Gene Therapy ?
What are the upcoming opportunities and trends for the Gene Therapy Market?
What are the recent industry trends that can be implemented to generate additional revenue streams for the Gene Therapy Market?
Who are the leading companies and what are their portfolios in Gene Therapy Market?
What segments are covered in the Gene Therapy Market?
Who are the key players in the Gene Therapymarket?

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♦ Explore the Revolutionary Products Powering Market Success

Past Size and Competitive Landscape
Past Pricing and price curve by region
Size, Share, Size Forecast by different segment
Dynamics Growth Drivers, Restraints, Opportunities, and Key Trends by Region
Segmentation A detailed analysis by segment with their sub-segments and Region
Competitive Landscape Profiles of selected key players by region from a strategic perspective

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