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Allogeneic Stem Cell Transplantation Market Exclusive Report with Detailed Study Analysis
According to the latest research by InsightAce Analytic, the Global Allogeneic Stem Cell Transplantation Market is valued at US$ 3.66 Bn in 2022, and it is expected to reach US$ 6.75 Bn by 2031, with a CAGR of 7.21% during the forecast period of 2023-2031.
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Allogeneic stem cell transplantation is a widely utilized medical procedure in which healthy blood-forming stem cells are donated to a patient by a genetically similar but non-identical donor, either related or unrelated. The global market for allogeneic stem cell transplantation is expanding rapidly, driven by advancements in genetic research for medical and diagnostic applications.
The increasing prevalence of chronic illnesses such as cancer, autoimmune disorders, and cardiovascular diseases is a key factor contributing to the growth of this market. In particular, blood cancers such as leukemia, multiple myeloma, and lymphoma have seen a significant rise in new cases over the past decade. For patients with high-risk or drug-resistant hematological malignancies, allogeneic hematopoietic stem cell transplantation presents a potentially curative treatment option. According to the World Health Organization, cancer accounted for approximately ten million deaths globally, underscoring the urgent need for innovative therapeutic solutions. The expanding patient population and growing demand for advanced treatment modalities are expected to drive market growth.
List Of Prominent Players In The Allogeneic Stem Cell Transplantation Market:
• Celgene Corporation
• Mesoblast Ltd.
• Pluristem Therapeutics Inc.
• MEDIPOST Co., Ltd.
• Takeda Pharmaceutical Company Limited
• Astellas Pharma Inc.
• Cellular Biomedicine Group, Inc.
• Biosolution Co., Ltd.
• StemCell Technologies Inc.
• Caladrius Biosciences, Inc.
• TiGenix N.V.
• ViaCord
• Vericel Corporation
• Regen Biopharma Inc.
• Gamida Cell Ltd.
• Histogenics Corporation
• BrainStorm Cell Therapeutics Inc.
• Lineage Cell Therapeutics, Inc.
• Bluebird Bio
• Sanofi
• Talaris Therapeutics.
• Others
Market Dynamics:
Drivers-
The rising demand for allogeneic stem cell transplantation is primarily driven by the increasing use of mesenchymal stem cells (MSCs) derived from mature tissues such as bone marrow, adipose tissue, and fat. These cells are gaining significant attention due to their immunomodulatory properties, making them highly suitable for regenerative medicine beyond conventional hematopoietic stem cell transplantation. As industry players expand their capabilities to leverage the clinical potential of allogeneic MSCs for broader therapeutic applications, the market is expected to witness substantial growth.
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Challenges:
Despite its growth potential, the allogeneic stem cell transplantation market faces several challenges. The high cost associated with infrastructure development, manufacturing processes, quality control measures, and skilled personnel required for transplantation procedures remains a significant barrier. Additionally, logistical expenses related to complex handling and transportation further impact affordability. In certain regions, limited insurance coverage and inadequate reimbursement policies restrict patient access to these advanced therapies. Furthermore, the COVID-19 pandemic disrupted healthcare services, leading to nationwide lockdowns, shortages of trained professionals, and delays in medical procedures, which slowed market expansion.
Regional Trends:
The North American allogeneic stem cell transplantation market is expected to hold a significant revenue share and experience robust growth due to advancements in medical technology and a well-established healthcare infrastructure. The region is home to specialized medical institutions, including transplant centers and oncology hospitals, equipped with cutting-edge technology and expertise necessary for successful hematopoietic stem cell transplantation (HSCT).
In Europe, the market also holds a considerable share, driven by the high prevalence of myeloid and lymphoid malignancies, solid tumors, and non-malignant diseases. Industrialized European nations are witnessing increasing demand for both allogeneic and autologous stem cell transplants, further supporting market expansion.
Recent Developments:
• In September 2023, Mesoblast collaborated with the Blood & Marrow Transplant Clinical Trials Network (BMT CTN) to conduct a clinical trial examining the effectiveness of its drug, Ryoncil (remestemcel-L), in treating steroid-refractory acute graft versus host disease (SR-aGvHD). BMT CTN will undertake the trial to assess the efficacy of Ryoncil in patients aged 12 and above who have shown inadequate response to prior treatments such as corticosteroids and a second-line drug like ruxolitinib.
• In Jan 2020, Astellas and Adaptimmune formed a partnership to collaborate on the development and marketing of stem-cell derived allogeneic CAR-T and TCR T-cell treatments. The cooperation utilized Adaptimmune's ability in identifying and confirming targets to create T-cell Receptors (TCRs), chimeric antigen receptors (CARs), and HLA-independent TCRs that could recognize surface epitopes regardless of the HLA profile of the tumor cell.
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Segmentation of Allogeneic Stem Cell Transplantation Market-
By Source
• Bone Marrow
• Peripheral Blood
• Umbilical Cord Blood
• Adipose Tissue
• Dental Pulp
• Others
By Cell Type
• Allogeneic MSCs (Allogenic Mesenchymal stem cells)
• Allogeneic HSCs (Allogeneic hematopoietic stem cells)
• Others
By Application
• Cancer
• Autoimmune Diseases
• Blood Disorders
• Cardiac Disorders
• Neurological Disorders
• Diabetes
• Others
By End User
• Hospitals
• Research Institutes
• Specialty Clinics
• Others
By Region-
North America-
• The US
• Canada
• Mexico
Europe-
• Germany
• The UK
• France
• Italy
• Spain
• Rest of Europe
Asia-Pacific-
• China
• Japan
• India
• South Korea
• South East Asia
• Rest of Asia Pacific
Latin America-
• Brazil
• Argentina
• Rest of Latin America
Middle East & Africa-
• GCC Countries
• South Africa
• Rest of the Middle East and Africa
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InsightAce Analytic is a market research and consulting firm that enables clients to make strategic decisions. Our qualitative and quantitative market intelligence solutions inform the need for market and competitive intelligence to expand businesses. We help clients gain a competitive advantage by identifying untapped markets, exploring new and competing technologies, segmenting potential markets, and repositioning products. Our expertise is in providing syndicated and custom market intelligence reports with an in-depth analysis with key market insights in a timely and cost-effective manner.https://www.insightaceanalytic.com/images_data/148861653.JPG
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