Immune Thrombocytopenic Purpura Pipeline: 30+ Pioneers Driving Innovation in Transformative Therapies | DelveInsight

The Immune Thrombocytopenic Purpura market is rapidly advancing and is fueled by groundbreaking research and innovative therapies from companies such as Sanofi, Takeda, Rigel Pharmaceuticals, and Bristol-Myers Squibb. These industry pioneers are transforming treatment strategies and redefining the future of Immune Thrombocytopenic Purpura, bringing new hope to patients worldwide.

DelveInsight's "Immune Thrombocytopenic Purpura Pipeline Insight, 2025" comprehensively analyzes the current clinical landscape and growth prospects in the Immune Thrombocytopenic Purpura market. The report covers disease insights, treatment guidelines, and a detailed pipeline assessment from preclinical to marketed stages. It includes drug mechanisms, clinical studies, regulatory progress, and key developments such as collaborations, mergers, funding, and designations.

For emerging Immune Thrombocytopenic Purpura drugs, the Immune Thrombocytopenic Purpura pipeline analysis report provides a 360° view of the therapeutics landscape by development point, product type, route of administration, molecule type, and MOA. The pipeline research covers business opportunities, challenges, future partnerships, strong competitors, and growth strategies.

Key Takeaways from the Immune Thrombocytopenic Purpura Pipeline Report
• DelveInsight's Immune Thrombocytopenic Purpura Pipeline analysis depicts a robust space with 30+ active players working to develop 25+ pipeline drugs for Immune Thrombocytopenic Purpura treatment.
• The leading Immune Thrombocytopenic Purpura companies include Sanofi, Takeda, Rigel Pharmaceuticals, Bristol-Myers Squibb, GlycoMimetics, Inclacumab, Prasugrel, Crovalimab, Sevuparin, and others are evaluating their lead assets to improve the Immune Thrombocytopenic Purpura treatment landscape.
• Key Immune Thrombocytopenic Purpura pipeline therapies in various stages of development include Rilzabrutinib, Mezagitamab, and others.
• In February 2025, Novartis' Ianalumab, for the treatment of primary immune thrombocytopenia, was granted FDA orphan designation, according to a post on the agency's website.

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Immune Thrombocytopenic Purpura Overview
Immune Thrombocytopenic Purpura (ITP) is an autoimmune disorder characterized by a low platelet count, leading to impaired blood clotting. Symptoms include easy bruising, superficial skin bleeding, mucosal bleeding, blood in urine or stools, and heavy menstrual flow in women. However, early diagnosis can be challenging as some patients may not show symptoms. Diagnosis is based on physical examination, medical history, and blood tests to assess platelet levels. Treatment options include steroids, immune globulins, and platelet-boosting drugs. In severe cases, splenectomy (surgical removal of the spleen) may be considered to prevent platelet destruction and improve platelet counts.

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Immune Thrombocytopenic Purpura Treatment Analysis: Drug Profile
Rilzabrutinib: Sanofi
Rilzabrutinib is a reversible, covalent Bruton's tyrosine kinase (BTK) inhibitor designed to increase platelet counts in ITP patients. It works by blocking inflammatory immune cells, preventing autoantibody-mediated platelet destruction, and inhibiting new autoantibody production without depleting B cells. Administered orally, it is currently being evaluated in a Phase III clinical trial for ITP. The FDA granted Fast Track designation for the therapy in November 2020.

Mezagitamab (TAK-079): Takeda
Mezagitamab is a fully human IgG1 monoclonal antibody that targets CD38, a cell surface molecule expressed on myeloma cells, plasma cells, plasmablasts, and natural killer (NK) cells, as well as activated T and B regulatory cells. By modulating immune responses, it aims to restore platelet levels in ITP patients. Currently, it is undergoing Phase II clinical trials for the treatment of ITP.

Key Immune Thrombocytopenic Purpura Therapies and Companies
• Rilzabrutinib: Sanofi
• Mezagitamab: Takeda

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Immune Thrombocytopenic Purpura Therapeutics Assessment
By Product Type
• Mono
• Combination
• Mono/Combination.

By Stage
• Late-stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I) along with the details of
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates

By Route of Administration
• Oral
• Parenteral
• Intravitreal
• Subretinal
• Topical

By Molecule Type
• Monoclonal Antibody
• Peptides
• Polymer
• Small molecule
• Gene therapy

Scope of the Immune Thrombocytopenic Purpura Pipeline Report
• Coverage: Global
• Key Immune Thrombocytopenic Purpura Companies: Sanofi, Takeda, Rigel Pharmaceuticals, Bristol-Myers Squibb, GlycoMimetics, Inclacumab, Prasugrel, Crovalimab, Sevuparin, and others.
• Key Immune Thrombocytopenic Purpura Pipeline Therapies: Rilzabrutinib, Mezagitamab, and others.

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Table of Contents
1. Introduction
2. Executive Summary
3. Immune Thrombocytopenic Purpura Pipeline: Overview
4. Analytical Perspective In-depth Commercial Assessment
5. Immune Thrombocytopenic Purpura Pipeline Therapeutics
6. Immune Thrombocytopenic Purpura Pipeline: Late-Stage Products (Phase III)
7. Immune Thrombocytopenic Purpura Pipeline: Late-Stage Products (Phase III)
8. Immune Thrombocytopenic Purpura Pipeline: Mid-Stage Products (Phase II)
9. Immune Thrombocytopenic Purpura Pipeline: Early Stage Products (Phase I)
10. Therapeutic Assessment
11. Inactive Products
12. Company-University Collaborations (Licensing/Partnering) Analysis
13. Key Companies
14. Key Products
15. Unmet Needs
16. Market Drivers and Barriers
17. Future Perspectives and Conclusion
18. Analyst Views
19. Appendix

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Jatin Vimal
jvimal@delveinsight.com
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Healthcare Consulting
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About DelveInsight
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This release was published on openPR.