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Key Influencer in the B-Cell Maturation Antigen (BCMA) Targeted Therapies Market 2025: Rising Incidence Of Multiple Myeloma Driver
B Cell Maturation Antigen BCMA Targeted TherapiesMarket Size
The b-cell maturation antigen (BCMA) targeted therapies market is forecasted to surge, driven by the escalating prevalence of multiple myeloma. This type of cancer predominantly occupies plasma cells, components of the immune system responsible for antibody production. This increasing prevalence is linked to factors including an elderly global population, advancements in diagnostic capabilities, and disparities in access to healthcare. Especially crucial in battling multiple myeloma, BCMA targeted therapies focus on the eradication of malignant plasma cells expressing BCMA, presenting a prospective approach for more efficient, pinpointed treatment. For instance, the American Cancer Society, a professional organization based in the US, reported that around 35,780 new multiple myeloma cases (comprising 19,520 male cases and 16,260 female cases) were identified in the US in August 2024. Furthermore, approximately 12,540 deaths are expected, of which 7,020 will be men and 5,520 women. Therefore, this growing prevalence is fueling the growth of the b-cell maturation antigen (BCMA) targeted therapies market.
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What is the projected compound annual growth rate (CAGR) of the b-cell maturation antigen (bcma) targeted therapies market from 2025 to 2034, and what factors influence it?
The market size of therapies targeting the B-cell maturation antigen (BCMA) has seen a significant increase in the past few years. The market is projected to rise from $12.17 billion in 2024 to $15.21 billion in 2025 with a compound annual growth rate (CAGR) of 25.0%. This surge during the historical period can be tied to the escalating emphasis on hematologic malignancies, increased investments in cancer research, surging requirement for personalized medicine, the expanding use of CAR-T cell therapies, and the overall increase in healthcare expenditure.
The market for B-cell maturation antigen (BCMA) targeted treatments is forecast to undergo substantial expansion in the coming years, with predictions showing that it will reach a value of $36.66 billion in 2029, reflecting a compound annual growth rate (CAGR) of 24.6%. This predicted growth during the forecast period is linked to several factors including an intensified concentration on cancer research, a shift towards targeted molecular markers, escalating cancer rates, an upswing in biotech investment and a rising utilization of cell and gene therapies. Forecast period trends that are anticipated to have a major impact include innovations such as CRISPR technology, progress in gene-editing technologies and the next wave of car-t cell therapies, improvements in targeted antibody-drug conjugates, and the production of off-the-shelf treatments.
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How are the latest trends influencing the growth of the b-cell maturation antigen (bcma) targeted therapies market?
Prominent players in the B-cell maturation antigen (BCMA) targeted therapies market are directing their efforts towards creating novel treatments like CAR-T cell therapy to improve the accuracy and effectiveness of targeting cancer cells. CAR-T cell therapy is a form of immunotherapy that modifies a patient's T cells to carry chimeric antigen receptors (CARs), enabling them to target and eradicate cancer cells. For instance, in April 2024, U.S. pharmaceutical giant Johnson & Johnson gained the approval of the U.S. Food and Drug Administration (FDA) for their product, CARVYKTI. CARVYKTI (ciltacabtagene autoleucel) is a BCMA-targeted, genetically modified autologous T-cell immunotherapy, intended to treat adult patients suffering from relapsed or refractory multiple myeloma who have undergone at least one previous line of therapy, and who are lenalidomide-resistant.
What are the major segments of the b-cell maturation antigen (bcma) targeted therapies market and their role in driving growth?
The B-cell maturation antigen (BCMA) targeted therapies market covered in this report is segmented -
1) By Product Type: Antibody Drug Conjugates, Chimeric Antigen Receptor T (CAR-T)-Cell Therapy, Bispecific Antibodies
2) By Indication Type: Acute Lymphoblastic Leukemia, Multiple Myeloma
3) By End User: Hospitals, Specialty Clinics, Home Care Settings
Subsegments:
1) By Antibody Drug Conjugates: BCMA-Targeted ADCs (Antibody-Drug Conjugates), Linker-Payload Technology-Based BCMA ADCs
2) By Chimeric Antigen Receptor T (CAR-T)-Cell Therapy: BCMA CAR-T Cells (Autologous), Allogeneic BCMA CAR-T Cells
3) By Bispecific Antibodies: BCMA x CD3 Bispecific Antibodies, BCMA x CD28 Bispecific Antibodies
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Which regions are key players in the growth of the b-cell maturation antigen (bcma) targeted therapies market?
North America was the largest region in the B-cell maturation antigen (BCMA) targeted therapies market in 2024. The regions covered in the B-cell maturation antigen (BCMA) targeted therapies market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
Who are the key firms paving the way for growth in the b-cell maturation antigen (bcma) targeted therapies market?
Major companies operating in the B-cell maturation antigen (BCMA) targeted therapies market are Bristol Myers Squibb Company, Novartis, GlaxoSmithKline (GSK), Takeda Pharmaceutical Company Limited, Amgen Inc, Regeneron Pharmaceuticals, Beigene, Arcellx Inc, Poseida Therapeutics, Legend Biotech Corporation, Cartesian Therapeutics, Juno Therapeutics, Sutro Biopharma Inc, CARsgen Therapeutics, Precision BioSciences, Eureka Therapeutics Inc, Cellectis, Teneobio Inc., Janssen Pharmaceuticals Companies, Allogene Therapeutics, Affimed, Bluebird Bio Inc.
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What Is Covered In The B-Cell Maturation Antigen (BCMA) Targeted Therapies Global Market Report?
•Market Size Forecast: Examine the b-cell maturation antigen (bcma) targeted therapies market size across key regions, countries, product categories, and applications.
•Segmentation Insights: Identify and classify subsegments within the b-cell maturation antigen (bcma) targeted therapies market for a structured understanding.
•Key Players Overview: Analyze major players in the b-cell maturation antigen (bcma) targeted therapies market, including their market value, share, and competitive positioning.
•Growth Trends Exploration: Assess individual growth patterns and future opportunities in the b-cell maturation antigen (bcma) targeted therapies market.
•Segment Contributions: Evaluate how different segments drive overall growth in the b-cell maturation antigen (bcma) targeted therapies market.
•Growth Factors: Highlight key drivers and opportunities influencing the expansion of the b-cell maturation antigen (bcma) targeted therapies market.
•Industry Challenges: Identify potential risks and obstacles affecting the b-cell maturation antigen (bcma) targeted therapies market.
•Competitive Landscape: Review strategic developments in the b-cell maturation antigen (bcma) targeted therapies market, including expansions, agreements, and new product launches.
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