Hydrophobic Interaction Chromatography Market to Reach $952.9 Million

Allied Market Research has published a report titled "Hydrophobic Interaction Chromatography Market by Product and Service (Product and Service), Sample Type (Monoclonal Antibodies, Vaccines, Cell Culture Sample, Plasma & Serum Sample, and Others), Application (Protein & Antibody Purification, Vaccine Development, Drug Discovery, and Food & Diet Supplement Development), and End User (Pharmaceutical & Biopharmaceutical Companies, Contract Research Organizations & Contract Manufacturing Organizations, Research & Academic Institutes, and Others): Global Opportunity Analysis and Industry Forecast, 2024-2033."

According to the report, the hydrophobic interaction chromatography market was valued at $461.9 million in 2023 and is estimated to reach $952.9 million by 2033, growing at a CAGR of 7.5% from 2024 to 2033.

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Prime Determinants of Growth

The increasing R&D expenditure in biopharmaceuticals, rising demand for biologics and monoclonal antibodies (mAbs), and growing adoption of biosimilars are key factors driving the hydrophobic interaction chromatography market. However, the shortage of a skilled workforce and high initial investment and operating costs hinder market growth. On the other hand, emerging markets and technological advancements in hydrophobic interaction chromatography (HIC) present new growth opportunities.

Market Segment Insights

Product Segment Dominance

By product and service, the product segment held the largest market share in 2023, accounting for more than four-fifths of the hydrophobic interaction chromatography market revenue. The segment is expected to maintain its leadership and register the highest CAGR of 7.6% during the forecast period. The demand for high-quality chromatography products, particularly in biopharmaceuticals and biotechnology industries, is fueling this growth. The increasing use of HIC for purifying monoclonal antibodies, therapeutic proteins, and vaccines is further boosting demand for advanced chromatography products.

Monoclonal Antibodies Lead the Sample Type Segment

By sample type, the monoclonal antibodies segment held the largest market share in 2023, accounting for around two-fifths of the hydrophobic interaction chromatography market revenue. This segment is projected to maintain its dominance and register the highest CAGR of 7.9% during the forecast period. The rise in demand for monoclonal antibodies for treating cancer, autoimmune disorders, and other chronic diseases is driving the need for efficient and reliable purification methods like HIC.

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Protein and Antibody Purification Drives Application Segment

By application, the protein and antibody purification segment accounted for more than two-fifths of the hydrophobic interaction chromatography market revenue in 2023 and is expected to remain the largest segment throughout the forecast period. The increasing demand for high-purity proteins and antibodies in the biopharmaceutical industry, particularly for monoclonal antibodies, therapeutic proteins, and vaccines, is fueling segment growth.

Additionally, the growing focus on biologics, biosimilars, and personalized medicine, along with stringent regulatory requirements, further strengthens this segment's expansion.

Pharmaceutical & Biopharmaceutical Companies Lead End-User Segment

By end user, the pharmaceutical and biopharmaceutical companies segment held the largest market share in 2023, contributing to half of the hydrophobic interaction chromatography market revenue. The demand for biologics, including monoclonal antibodies, therapeutic proteins, and vaccines, which require efficient purification techniques like HIC, is driving growth in this segment.

The contract research organizations (CROs) and contract manufacturing organizations (CMOs) segment is expected to register the highest CAGR of 7.9% during the forecast period. The increasing trend of outsourcing in the pharmaceutical and biotechnology industries, where CROs and CMOs are relied upon for research, development, and manufacturing processes, is fueling market expansion.

Regional Insights

North America dominated the market in 2023, accounting for around two-fifths of the global hydrophobic interaction chromatography market revenue. The region's well-established biopharmaceutical industry, strong presence of pharmaceutical and biotechnology companies, and extensive use of HIC for biologics purification contribute to its market leadership.

However, the Asia-Pacific region is expected to register the highest CAGR of 8.2% during the forecast period. The growing demand for biologics, biosimilars, and therapeutic proteins is driving the adoption of advanced purification technologies like HIC. Additionally, lower production costs, expanding contract research and manufacturing services, increasing investments in healthcare infrastructure, and supportive government policies are fueling market growth in this region.

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Leading Market Players

• Tosoh Corporation
• Thermo Fisher Scientific Inc.
• Danaher Corporation
• Agilent Technologies, Inc.
• Merck KGaA
• Sepax Technologies, Inc.
• Sartorius AG
• Geno Technology, Inc.
• Waters Corporation
• KNAUER Wissenschaftliche Geräte GmbH
• Bio-Rad Laboratories, Inc.

These key players are actively adopting strategies such as acquisitions, product innovations, and technological advancements to strengthen their market position and enhance their global presence.

Frequently Asked Questions?

Q1. What is the base year of hydrophobic interaction chromatography market in the globe?

Q2. What is the leading application of hydrophobic interaction chromatography market?

Q3. Which is the largest regional market for hydrophobic interaction chromatography?

Q4. What is the estimated industry size of hydrophobic interaction chromatography?

Q5. Which are the top companies to hold the market share in hydrophobic interaction chromatography?

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