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Upstream Bioprocessing Market Forecast 2025-2034: Analysing Major Trends, Opportunities, and Growth Drivers

03-27-2025 07:28 AM CET | Health & Medicine

Press release from: The Business Research Company

Upstream Bioprocessing

Upstream Bioprocessing

Which drivers are expected to have the greatest impact on the over the upstream bioprocessing market's growth?
The outsourcing of biopharmaceutical manufacturing is expected to drive the growth of the upstream bioprocessing market. The outsourcing of manufacturing processes, particularly in biopharmaceutical production, is a growing trend due to its cost efficiency and ability to provide specialized expertise. Outsourcing allows companies to focus on core competencies while leveraging external manufacturers for production stages. As biopharmaceutical companies increasingly outsource production, particularly in upstream processes like cell culture and fermentation, demand for upstream bioprocessing services is expected to rise. According to BDO USA, by 2025, contract development and manufacturing organizations are expected to control 44% of global mammalian capacity, further highlighting the importance of outsourcing in biopharmaceutical manufacturing and its impact on the growth of the upstream bioprocessing market.

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What is the future CAGR of the upstream bioprocessing market, and how will it impact industry expansion?
The upstream bioprocessing market has expanded rapidly, projected to grow from $12.03 billion in 2024 to $13.66 billion in 2025, at a CAGR of 13.6%. Growth is fueled by the demand for process optimization, safe and efficient biomolecule production, commercial success of bio-therapeutics, adoption of process analytical technology, rising chronic disease prevalence, and increased biosimilar research.

The upstream bioprocessing market is expected to grow to $22.43 billion by 2029 at a CAGR of 13.2%. Growth drivers include increased adoption of single-use bioreactors, rising demand for biopharmaceutical outsourcing, and rapid expansion of the biotech industry. Key trends include advanced filtration technologies, increased R&D investments, and new technological innovations in upstream bioprocessing.

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What are the most significant trends transforming the upstream bioprocessing market today?
In the upstream bioprocessing market, companies are innovating with advanced bioreactors to enhance the performance, scalability, and flexibility of cell culture processes. Cytiva, a US-based life sciences company, introduced the X-platform bioreactors in April 2023. These bioreactors support single-use bioprocessing and feature a modular design, optimizing operations without requiring custom hardware. The design also includes improved cable management and an online Bioreactor Scaler tool for determining optimal scale-up parameters.

Which key market segments comprise the upstream bioprocessing market and drive its revenue growth?
The upstream bioprocessing market covered in this report is segmented -

1) By Product type: Bioreactors, Fermenters, Cell Culture Media, Filters, Bags And Containers
2) By Workflow: Media Preparation, Cell Culture, Cell Separation
3) By Usage type: Single-Use, Multi-Use
4) By Mode: In House, Outsourced
5) By End User: Contract Development and Manufacturing Organization (CDMOs) Or Contract Research Organization (CROs), Research And Academic Institutes, Biopharmaceutical Companies

Subsegments:
1) By Bioreactors: Single-Use Bioreactors, Multi-Use Bioreactors
2) By Fermenters: Laboratory Fermenters, Pilot Scale Fermenters, Industrial Fermenters
3) By Cell Culture Media: Powdered Media, Liquid Media
4) By Filters: Sterile Filters, Air Filters, Capsule Filters
5) By Bags And Containers: Single-Use Bags, Bioprocess Containers, Storage Bags

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What regions are at the forefront of upstream bioprocessing market expansion?
North America was the largest region in the upstream bioprocessing market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the upstream bioprocessing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

Who are the leading players fueling growth in the upstream bioprocessing market?
Major companies operating in the upstream bioprocessing market are Thermo Fisher Scientific Inc., Danaher Corp, Merck KGaA, GE HealthCare Technologies, Parker Hannifin Corp, Corning Inc., AGC Biologics, Avantor, AGC Inc., Boehringer Ingelheim International GmbH, Catalent Inc., Sartorius AG, Entegris Inc., Getinge AB, Bio-Rad Laboratories Inc., Samsung Biologics Co. Ltd., Eppendorf AG, Repligen Corporation, Takara Bio Inc., KBI Biopharma Inc., Rentschler Biopharma SE, Just Biotherapeutics Inc., PBS Biotech Inc., Stobbe Group, Applikon Biotechnology

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What Is Covered In The Upstream Bioprocessing Global Market Report?

•Market Size Forecast: Examine the upstream bioprocessing market size across key regions, countries, product categories, and applications.
•Segmentation Insights: Identify and classify subsegments within the upstream bioprocessing market for a structured understanding.
•Key Players Overview: Analyze major players in the upstream bioprocessing market, including their market value, share, and competitive positioning.
•Growth Trends Exploration: Assess individual growth patterns and future opportunities in the upstream bioprocessing market.
•Segment Contributions: Evaluate how different segments drive overall growth in the upstream bioprocessing market.
•Growth Factors: Highlight key drivers and opportunities influencing the expansion of the upstream bioprocessing market.
•Industry Challenges: Identify potential risks and obstacles affecting the upstream bioprocessing market.
•Competitive Landscape: Review strategic developments in the upstream bioprocessing market, including expansions, agreements, and new product launches.

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