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Global Actinic Keratosis Market Projected to Surpass $10.58 Billion by 2029 with 5.8% Annual Growth

03-25-2025 05:36 AM CET | Health & Medicine

Press release from: The Business Research Company

Actinic Keratosis

Actinic Keratosis

What market dynamics are playing a key role in accelerating the growth of the actinic keratosis market?
The rising incidence of severe sunburns is expected to accelerate the growth of the actinic keratosis market. Severe sunburns result from excessive exposure to ultraviolet (UV) radiation, causing redness, pain, swelling, and sometimes blistering. Factors such as prolonged UV exposure, inadequate sun protection, increased outdoor activities during peak UV hours, and climate change-induced temperature rises contribute to sunburn cases. Sunburns can lead to actinic keratosis by causing DNA damage in skin cells through UV radiation, leading to mutations that interfere with normal cell function and contribute to the formation of precancerous lesions, especially after repeated sun exposure. For instance, in May 2024, Melanoma Focus, a UK-based charity, reported that in 2022-23, there were 201 hospital admissions due to sunburn, including 89 children and 25 infants under one year old. Additionally, 66% of UK adults aged 16-65 recalled experiencing sunburn during childhood, with 65% suffering from severe sunburn with blisters at least once. This number increased to 77% for individuals with light, pale, or white skin. Therefore, the rising incidence of severe sunburns is driving the actinic keratosis market.

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How will the growth rate of the actinic keratosis market shape industry trends by 2034?
The actinic keratosis market has seen consistent growth over the years. It is projected to grow from $7.95 billion in 2024 to $8.44 billion in 2025, at a CAGR of 6.1%. The key factors behind this historical growth include increased exposure to UV radiation, an aging population, greater awareness of skin cancer, a rising prevalence of actinic keratosis, improved healthcare infrastructure, higher disposable incomes, government initiatives, and an increased focus on preventive skincare.

The actinic keratosis market size is anticipated to witness substantial growth in the upcoming years. By 2029, it is projected to reach $10.58 billion, growing at a compound annual growth rate (CAGR) of 7.4%. The expected growth is fueled by the emergence of advanced therapies, improvements in AI-powered diagnostic tools, a rising adoption of combination treatments, increasing demand for non-invasive procedures, the growing use of teledermatology, broader applications of photodynamic therapy, increased awareness of cosmetic outcomes, the development of targeted biologic treatments, rising healthcare investment in emerging markets, and a stronger focus on early detection and prevention. Major trends during this period include AI-driven diagnostic tools, machine learning for lesion analysis, advancements in photodynamic therapy, wearable UV monitoring devices, nanotechnology-based drug delivery systems, 3D imaging for personalized treatments, portable home-based phototherapy devices, biosensors for early detection, automated lesion classification software, and hydrogel-based therapeutic systems.

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What trends are poised to drive the future success of the actinic keratosis market?
In the actinic keratosis market, major players are focusing on topical ointments to treat precancerous lesions and improve patient compliance with shorter treatment durations. A key example is Klisyri (tirbanibulin), developed by Almirall SA, a Spain-based biopharmaceutical company. In June 2024, Klisyri received FDA approval for its expanded use on up to 100 cm2 of affected skin, offering a more targeted treatment for actinic keratosis on the face or scalp.

Which primary segments of the actinic keratosis market are driving growth and industry transformations?
The actinic keratosis market covered in this report is segmented -

1) By Treatment Type: Topical Treatment, Surgical Procedure, Photodynamic Therapy, Other Treatment Types
2) By Distribution Channels: Hospital Pharmacies, Drug Stores And Retail Pharmacies, Online Providers
3) By End-User: Hospitals, Dermatology Clinics, Spas And Rejuvenation Centers, Homecare Settings, Other End-Users

Subsegments:
1) By Topical Treatment: 5-Fluorouracil (5-FU), Imiquimod, Diclofenac, Ingenol Mebutate, Retinoids
2) By Surgical Procedure: Cryotherapy, Curettage And Electrodessication, Excision
3) By Photodynamic Therapy: Aminolevulinic Acid (ALA) Plus Light Therapy, Methyl Aminolevulinate (MAL) Plus Light Therapy
4) By Other Treatment Types: Laser Therapy, Chemical Peels, Combination Therapies

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Which geographical regions are pioneering growth in the actinic keratosis market?
North America was the largest region in the actinic keratosis market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the actinic keratosis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

Who are the influential players reshaping the actinic keratosis market landscape?
Major companies operating in the actinic keratosis market are Pfizer Inc., F. Hoffmann-La Roche AG, Merck & Co. Inc., AbbVie Inc., Sanofi S.A., Bristol-Myers Squibb, Novartis AG, GSK plc, Amgen Inc., Bausch Health Companies Inc., Perrigo Company plc, Galderma SA, Incyte Corporation, Leo Pharma Inc., Almirall S.A., Athenex Inc., G&E Herbal Biotechnology Co. Ltd., Aclaris Therapeutics Inc., Biofrontera Inc., Hill Dermaceuticals Inc.

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What Is Covered In The Actinic Keratosis Global Market Report?

•Market Size Forecast: Examine the actinic keratosis market size across key regions, countries, product categories, and applications.
•Segmentation Insights: Identify and classify subsegments within the actinic keratosis market for a structured understanding.
•Key Players Overview: Analyze major players in the actinic keratosis market, including their market value, share, and competitive positioning.
•Growth Trends Exploration: Assess individual growth patterns and future opportunities in the actinic keratosis market.
•Segment Contributions: Evaluate how different segments drive overall growth in the actinic keratosis market.
•Growth Factors: Highlight key drivers and opportunities influencing the expansion of the actinic keratosis market.
•Industry Challenges: Identify potential risks and obstacles affecting the actinic keratosis market.
•Competitive Landscape: Review strategic developments in the actinic keratosis market, including expansions, agreements, and new product launches.

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