Prominent Advanced Therapy Medicinal Products Contract Development And Manufacturing Organization (CDMO) Market Trend for 2025: Transforming Cell Therapy Manufacturing With Innovations In Advanced Therapy Medicinal Products

How Are the key drivers contributing to the expansion of the advanced therapy medicinal products contract development and manufacturing organization (cdmo) market?
The growth of the advanced therapy medicinal products CDMO market is anticipated to be driven by the escalating number of clinical trials. These trials, conducted in humans, are design to test the safety and effectiveness of various medical interventions, including drugs and preventive measures. There's been a surge in clinical trial numbers to cater to the rising need for groundbreaking treatments and contend with the escalating global disease burden. Advanced therapy medicinal products precipitate a rising demand for CDMO manufacturing services, hence, taking advantage of specialized expertise and facilities. Manufacturing optimization, scalability assurance, and maintenance of quality to satisfy larger clinical and commercial needs are achieved via clinical trial data. For instance, the Association of the British Pharmaceutical Industry, a UK-based trade organization, reported in November 2023 that there was a minor 4.3% increase in the initiation of industry clinical trials per year in the UK, from 394 in 2021 to 411 in 2022. Consequently, the burgeoning number of clinical trials stimulates the growth of the advanced therapy medicinal products CDMO market.

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What growth opportunities are expected to drive the advanced therapy medicinal products contract development and manufacturing organization (cdmo) market's CAGR through 2034?
The market size of the contract development and manufacturing organization (CDMO) for advanced therapy medicinal products (ATMP) has seen a significant expansion in the recent past. It's predicted that the growth will surge from $5.31 billion in 2024 to $6.22 billion in 2025, with a compound annual growth rate (CAGR) of 17.0%. This growth during the historical period is as a result of factors including the rise in the number of ATMP clinical trials, growing understanding and faith among scientists about the advantages of advanced therapy, the existence of numerous ATMP CDMOs, increased endeavours to create new therapies for a range of diseases, and beneficial government initiatives.

The market size for advanced therapy medicinal products contract development and manufacturing organization (CDMO) is predicted to experience significant expansion in the coming years, reaching $11.53 billion in 2029 with a compound annual growth rate (CAGR) set at 16.7%. This surge during the forecast period is credited to factors such as elevated investment levels by CDMOs, the rise of new key players in the cell and gene therapy (CGT) field, an increase in grants and investments dedicated to cell and gene therapies development, a rise in pharmaceutical R&D expenditure, and increasing numbers of clinical trials for ATMPs. Dominant trends during this period are expected to be improvements in AAV biomanufacturing facilities, the expansion of cell and gene therapy production, advanced technology in cell and gene therapy, a need for access to progressive platforms and technologies, and the inclusion of advanced technologies like CRISPR and next-generation sequencing for improved accuracy.

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What are the emerging trends shaping the future of the advanced therapy medicinal products contract development and manufacturing organization (cdmo) market?
Big corporations involved in the CDMO sector for advanced therapy medicinal products are innovating advanced cell therapy production services. This attempt is to address major complications in cell therapy production and enhance the advancement activities of their counterparts. These services related to manufacturing organization contracts and developments come with a variety of options from the beginning of preclinical development to the final stages of clinical trials and commercialization. For example, Pluristem Therapeutics Inc., a biotech firm based in Israel focusing on converting cells into solutions, initiated a new business segment named PluriCDMO in January 2024. This entity offers cell therapy manufacturing and employs a patented bioreactor system that facilitates 3D cell multiplication. This aids in the production of diverse cell types like stem cells, induced pluripotent stem cells, exosomes, and immune therapies. The goal of PluriCDMO is to deliver valuable, high-quality medicine to patients while ensuring a consistent batch-to-batch production in a good manufacturing practice environment that is both scalable and cost-effective.

Which growth-oriented segments of the advanced therapy medicinal products contract development and manufacturing organization (cdmo) market are leading the industry's development?
The advanced therapy medicinal products contract development and manufacturing organization (CDMO) market covered in this report is segmented -

1) By Product: Gene Therapy, Cell Therapy, Tissue Engineered
2) By Phase: Phase I, Phase II, Phase III, Phase IV
3) By Indication: Oncology, Cardiology, Central Nervous System And Musculoskeletal, Infectious Disease, Dermatology, Endocrine, Metabolic, Genetic, Immunology And Inflammation, Ophthalmology, Hematology

Subsegments:
1) By Gene Therapy: Viral Vectors, Non-Viral Vectors, Dna Or Rna-Based Products
2) By Cell Therapy: Autologous Cell Therapy, Allogeneic Cell Therapy, Stem Cell Therapy
3) By Tissue Engineered: Skin Substitutes, Cartilage And Bone Tissue, Vascular Grafts And Organs

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What regions are leading the charge in the advanced therapy medicinal products contract development and manufacturing organization (cdmo) market?
North America was the largest region in the advanced therapy medicinal product contract development and manufacturing organization (CDMO) market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the advanced therapy medicinal products contract development and manufacturing organization (CDMO) market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

What companies are at the forefront of innovation in the advanced therapy medicinal products contract development and manufacturing organization (cdmo) market?
Major companies operating in the advanced therapy medicinal products contract development and manufacturing organization (CDMO) market are Thermo Fisher Scientific Inc., Merck KGaA, Resonac Corporation, Lonza Group AG, Catalent Inc., Charles River Laboratories International Inc., Recipharm AB, KBI Biopharma, Takara Bio Inc., Rentschler Biopharma SE, Ajinomoto Co. Inc., ElevateBio LLC, Fujifilm Diosynth Biotechnologies, Axplora Group GmbH, WuXi Advanced Therapies Inc., Celonic Group, Batavia Biosciences B.V., BioCentriq, Cytovance Biologics, Andelyn Biosciences, Genezen, AGC Biologics, ABL Manufacturing, Minaris Regenerative Medicine, Porton Advanced Solutions

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What Is Covered In The Advanced Therapy Medicinal Products Contract Development And Manufacturing Organization (CDMO) Global Market Report?

•Market Size Forecast: Examine the advanced therapy medicinal products contract development and manufacturing organization (cdmo) market size across key regions, countries, product categories, and applications.
•Segmentation Insights: Identify and classify subsegments within the advanced therapy medicinal products contract development and manufacturing organization (cdmo) market for a structured understanding.
•Key Players Overview: Analyze major players in the advanced therapy medicinal products contract development and manufacturing organization (cdmo) market, including their market value, share, and competitive positioning.
•Growth Trends Exploration: Assess individual growth patterns and future opportunities in the advanced therapy medicinal products contract development and manufacturing organization (cdmo) market.
•Segment Contributions: Evaluate how different segments drive overall growth in the advanced therapy medicinal products contract development and manufacturing organization (cdmo) market.
•Growth Factors: Highlight key drivers and opportunities influencing the expansion of the advanced therapy medicinal products contract development and manufacturing organization (cdmo) market.
•Industry Challenges: Identify potential risks and obstacles affecting the advanced therapy medicinal products contract development and manufacturing organization (cdmo) market.
•Competitive Landscape: Review strategic developments in the advanced therapy medicinal products contract development and manufacturing organization (cdmo) market, including expansions, agreements, and new product launches.

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