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Impact Of Rising Cancer Prevalence On The Cell-Free DNA (cfDNA) Testing Market Driver: Leading Transformation in the Cell Free DNA (cfDNA) Testing Market in 2025

03-19-2025 05:07 AM CET | Health & Medicine

Press release from: The Business Research Company

Cell Free DNA (cfDNA) Testing

Cell Free DNA (cfDNA) Testing

Which drivers are expected to have the greatest impact on the over the cell free dna (cfdna) testing market's growth?
The escalating incidence of cancer is seen as a significant factor in driving progress in the cell-free DNA (cfDNA) testing market. Cancer, a multifaceted collection of diseases, is marked by abnormal cell growth and infiltration that can ravage healthy tissue and cause excessive body damage if not regulated. The increased occurrence of cancer can be traced to aging demographics, lifestyle modifications, environmental factors, and improvements in detection and diagnostic methodologies. cfDNA testing is crucial in detecting cancer-linked genetic anomalies at an early stage, often even before visible symptoms manifest. The benefit of this early detection is that it facilitates prompt treatment, boosting a patient's chances of recovery and survival rates by locating cancer in its primary stages. For example, the World Health Organization (WHO), based in Switzerland, stated in February 2024 that they anticipated over 35 million new cancer cases in 2050, which is a 77% surge compared to the 20 million cased predicted in 2022. Hence, it is suggested that the increasing incidence of cancer is fuelling growth in the cell-free DNA (cfDNA) testing market.

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What is the future CAGR of the cell free dna (cfdna) testing market, and how will it impact industry expansion?
The market size for cell free dna (cfDNA) testing has experienced remarkable growth in the past few years. It's projected to inflate from $8.74 billion in 2024, advancing to $10.86 billion in 2025, representing a compound annual growth rate (CAGR) of 24.2%. The dramatic growth during the historic period is attributable to an increased implementation of cfDNA testing in prenatal care, intensified usage of cfDNA analysis, surging interest in cfDNA studies within diverse medical specialties, and a rising trend in obtaining endorsements from regulatory authorities.

In the coming years, significant growth is anticipated in the cell free dna (cfDNA) testing market, with projections indicating it will increase to $25.56 billion by 2029 - an impressive compound annual growth rate (CAGR) of 23.9%. Several factors contributing to this expected growth are the transition to personalized healthcare, improvements in medical infrastructure, an aging demographic and the rising prevalence of cancer. Additional drivers include the growing adoption of precision medicine, enhanced awareness and acceptance of liquid biopsy methods, and increased investment in cfDNA research. Key trends observed in the forecasted period are the increased adoption of liquid biopsy technology, advancements in Next-Generation Sequencing (NGS), the integration of AI and machine learning in cfDNA testing, the development of on-the-spot cfDNA tests, and the use of cloud-based platforms for data storage and analysis.

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What are the most significant trends transforming the cell free dna (cfdna) testing market today?
Cell-free DNA (cfDNA) testing market's leading entities are investing in the creation of cutting-edge technologies like liquid biopsy tests. These tests increase the sensitivity, specificity, and accuracy of detecting cancer-related mutations and genetic alterations. Oncologists utilize liquid biopsy tests as diagnostic tools to evaluate circulating cell-free DNA that tumor cells release. This helps formulate personalized, specific therapy schedules. Laboratory Corporation of America Holdings (Labcorp), a life sciences company from the US, introduced Labcorp Plasma Focus in May 2023. This is a new type of liquid biopsy test developed for patients battling advanced or metastatic solid tumors. Through a straightforward blood draw, the test evaluates circulating cell-free DNA (cfDNA) released by tumor cells. It is not invasive and delivers swift results. It aims to bolster precision oncology access by identifying and targeting clinically significant biomarkers in numerous common cancers, like non-small cell lung, colorectal, breast, esophageal, gastroesophageal junction, gastric cancers, and melanoma.

Which key market segments comprise the cell free dna (cfdna) testing market and drive its revenue growth?
The cell free dna (cfDNA) testing market covered in this report is segmented -

1) By Product: Donor-Derived Cell-Free DNA, Circulating Cell-Free Tumor DNA, Cell-Free Fetal DNA
2) By Platforms: Next Generation Sequencing (NGS), rPCR And Multiplexed PCR, qPCR And dPCR, Other platforms
3) By Application: Oncology, Non-Invasive Prenatal Test (NIPT), Gynecology, Transplantation, Other Applications

Subsegments:
1) By Donor-Derived Cell-Free DNA: Organ Transplant Monitoring, Graft Rejection Detection
2) By Circulating Cell-Free Tumor DNA: Cancer Detection, Minimal Residual Disease Monitoring, Liquid Biopsy
3) By Cell-Free Fetal DNA: Non-Invasive Prenatal Testing (NIPT), Fetal Genetic Disorder Screening

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North America was the largest region in the cell-free DNA (cfDNA) testing market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the cell free DNA (cfDNA) testing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

Who are the leading players fueling growth in the cell free dna (cfdna) testing market?
Major companies operating in the cell free DNA (cfDNA) testing market are F. Hoffmann-La Roche Ltd., Thermo Fisher Scientific Inc., Laboratory Corporation of America Holdings, Quest Diagnostics Incorporated, Agilent Technologies Inc., Illumina Inc., Qiagen N.V., Exact Sciences Corporation, Bio-Techne Corporation, Natera Inc., Myriad Genetics Inc., NeoGenomics Laboratories Inc., Invitae Corporation, Foundation Medicine Inc., Guardant Health Inc., Integrated DNA Technologies Inc., Caris Life Sciences Inc., Twist Bioscience Corporation, Adaptive Biotechnologies Corporation, Biodesix Inc., Biocept Inc., Personal Genome Diagnostics Inc., Agena Bioscience Inc., Menarini Silicon Biosystems Inc., Circulogene Theranostics LLC

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What Is Covered In The Cell Free DNA (cfDNA) Testing Global Market Report?

•Market Size Forecast: Examine the cell free dna (cfdna) testing market size across key regions, countries, product categories, and applications.
•Segmentation Insights: Identify and classify subsegments within the cell free dna (cfdna) testing market for a structured understanding.
•Key Players Overview: Analyze major players in the cell free dna (cfdna) testing market, including their market value, share, and competitive positioning.
•Growth Trends Exploration: Assess individual growth patterns and future opportunities in the cell free dna (cfdna) testing market.
•Segment Contributions: Evaluate how different segments drive overall growth in the cell free dna (cfdna) testing market.
•Growth Factors: Highlight key drivers and opportunities influencing the expansion of the cell free dna (cfdna) testing market.
•Industry Challenges: Identify potential risks and obstacles affecting the cell free dna (cfdna) testing market.
•Competitive Landscape: Review strategic developments in the cell free dna (cfdna) testing market, including expansions, agreements, and new product launches.

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