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Advanced Kidney Cancer Clinical Pipeline | 50+ Companies Transforming the Future of Treatment
Advanced Kidney Cancer Clinical Pipeline
DelveInsight's 'Advanced Kidney Cancer Pipeline Insight 2024' report provides comprehensive global coverage of pipeline Advanced Kidney Cancer therapies in various stages of clinical development. Major pharmaceutical companies are working to advance the pipeline space and future growth potential of the Advanced Kidney Cancer pipeline domain.
For emerging Advanced Kidney Cancer drugs, the Advanced Kidney Cancer pipeline analysis report provides a 360° view of the therapeutics landscape by development point, product type, route of administration, molecule type, and MOA. The pipeline research covers business opportunities, challenges, future partnerships, strong competitors, and growth strategies.
Key Takeaways from the Advanced Kidney Cancer Pipeline Report
• DelveInsight's Advanced Kidney Cancer Pipeline analysis depicts a robust space with 50+ active players working to develop 55+ pipeline drugs for Advanced Kidney Cancer treatment.
• The leading Advanced Kidney Cancer companies include Janux Therapeutics, Infinity Pharmaceuticals, Merck Sharp & Dohme, Xencor, Exelixis, X4 Pharmaceuticals, Nykode Therapeutics, Tarus Therapeutics, AstraZeneca, RemeGen, NiKang Therapeutics, NGM Biopharmaceuticals, MedImmune, and others are evaluating their lead assets to improve the Advanced Kidney Cancer treatment landscape.
• Key Advanced Kidney Cancer pipeline therapies in various stages of development include Savolitinib, Relatlimab, JANX008, TQB2450, Tc-99m Pentetate, BMS-986488, Belzutifan, DFF332, RAD001, PDR001, NIR178, Atezolizumab, Zanzalintinib, and others.
• In Feb 2025, Telix Pharmaceuticals announced that the FDA accepted the Biologics License Application (BLA) for TLX250-CDx (Zircaix®), a breakthrough kidney cancer PET imaging agent. The FDA granted a Priority Review and set a PDUFA date of August 27, 2025, for a potential U.S. launch.
Request a sample and discover the recent breakthroughs happening in the Advanced Kidney Cancer pipeline landscape @ https://www.delveinsight.com/report-store/advanced-kidney-cancer-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=jpr
Advanced Kidney Cancer Overview
Advanced kidney cancer, primarily advanced renal cell carcinoma (RCC), is the most common kidney cancer in adults, accounting for over 90% of cases. Other types include transitional cell carcinomas of the renal pelvis, which resemble bladder cancers, and the rare renal sarcoma. Major risk factors for RCC include smoking, obesity-particularly in women-high blood pressure, chronic renal failure, and occupational exposure to harmful chemicals. Reducing tobacco use and excess body weight could significantly lower RCC incidence. Conversely, moderate alcohol intake, a diet rich in fruits and vegetables, and long-term fatty fish consumption are associated with a lower risk. Genetic mutations also play a role, with VHL mutations linked to both sporadic and familial clear cell RCC, while MET mutations are characteristic of familial papillary RCC.
Managing advanced or metastatic RCC requires a multidisciplinary approach, involving oncology specialists, nurses, dietitians, and pharmacists to optimize treatment and monitor toxicities. Accurate staging is essential for effective management, guiding treatment decisions. Early-stage RCC (Stage 1a and 1b) is typically treated with nephron-sparing surgery or radical nephrectomy, followed by imaging surveillance. Stages 2 and 3 often require radical nephrectomy with structured follow-ups. In Stage 4, systemic targeted therapies like VEGF-TKIs and rapamycin inhibitors are preferred, while nephrectomy combined with immunotherapy has shown improved survival outcomes. Regular imaging and patient evaluations ensure treatment efficacy and safety, emphasizing the importance of comprehensive patient education on side effects and management strategies.
Find out more about Advanced Kidney Cancer medication @ https://www.delveinsight.com/report-store/advanced-kidney-cancer-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=jpr
Advanced Kidney Cancer Treatment Analysis: Drug Profile
Savolitinib: AstraZeneca
Savolitinib is an oral, potent, and highly selective MET TKI that has demonstrated clinical activity in advanced solid tumors. It blocks atypical activation of the MET receptor tyrosine kinase pathway that occurs because of mutations or gene amplification. The drug is currently being evaluated under Phase III clinical trial for the treatment of advanced kidney cancer.
Relatlimab: Bristol-Myers Squibb
Relatlimab is a lymphocyte activation gene-3 (LAG-3) blocking antibody and is expressed in a recombinant CHO cell line. The drug is currently being evaluated under Phase II clinical trial for the treatment of patients with advanced kidney cancer.
Key Advanced Kidney Cancer Therapies and Companies
• Savolitinib: AstraZeneca
• Relatlimab: Bristol-Myers Squibb
• JANX008: Janux Therapeutics
• TQB2450: Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
• Tc-99m Pentetate: NYU Langone Health
• BMS-986488: Bristol-Myers Squibb
• Belzutifan: Merck Sharp & Dohme LLC
• DFF332/RAD001/PDR001/ NIR178: Novartis Pharmaceuticals
• Atezolizumab: Hoffmann-La Roche
• Zanzalintinib: Qian Qin
Learn more about the novel and emerging Advanced Kidney Cancer pipeline therapies @ https://www.delveinsight.com/report-store/advanced-kidney-cancer-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=jpr
Advanced Kidney Cancer Therapeutics Assessment
By Product Type
• Mono
• Combination
• Mono/Combination.
By Stage
• Late stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I) along with the details of
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates
By Route of Administration
• Intravenous
• Subcutaneous
• Oral
• Intramuscular
By Molecule Type
• Monoclonal antibody
• Small molecule
• Peptide
Scope of the Advanced Kidney Cancer Pipeline Report
• Coverage: Global
• Key Advanced Kidney Cancer Companies: Janux Therapeutics, Infinity Pharmaceuticals, Merck Sharp & Dohme, Xencor, Exelixis, X4 Pharmaceuticals, Nykode Therapeutics, Tarus Therapeutics, AstraZeneca, RemeGen, NiKang Therapeutics, NGM Biopharmaceuticals, MedImmune, and others.
• Key Advanced Kidney Cancer Pipeline Therapies: Savolitinib, Relatlimab, JANX008, TQB2450, Tc-99m Pentetate, BMS-986488, Belzutifan, DFF332, RAD001, PDR001, NIR178, Atezolizumab, Zanzalintinib, and others.
Dive deep into rich insights for drugs used for Advanced Kidney Cancer treatment; visit @ https://www.delveinsight.com/report-store/advanced-kidney-cancer-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=jpr
Table of Contents
1. Introduction
2. Executive Summary
3. Advanced Kidney Cancer Pipeline: Overview
4. Analytical Perspective In-depth Commercial Assessment
5. Advanced Kidney Cancer Pipeline Therapeutics
6. Advanced Kidney Cancer Pipeline: Late-Stage Products (Phase III)
7. Advanced Kidney Cancer Pipeline: Late-Stage Products (Phase III)
8. Advanced Kidney Cancer Pipeline: Mid-Stage Products (Phase II)
9. Advanced Kidney Cancer Pipeline: Early Stage Products (Phase I)
10. Therapeutic Assessment
11. Inactive Products
12. Company-University Collaborations (Licensing/Partnering) Analysis
13. Key Companies
14. Key Products
15. Unmet Needs
16. Market Drivers and Barriers
17. Future Perspectives and Conclusion
18. Analyst Views
19. Appendix
Contact Us:
Jatin Vimal
jvimal@delveinsight.com
+14699457679
Healthcare Consulting
https://www.delveinsight.com/consulting-services
About DelveInsight
DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve.
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