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Antisense Oligonucleotides Market reached US$ 2,985.97 million in 2024 and is expected to reach US$ 5,286.96 million by 2033 | Sarepta Therapeutics, Alnylam Pharmaceuticals, Inc. Percheron Therapeutics.
The Global Antisense Oligonucleotides Market reached US$ 2,985.97 million in 2024 and is expected to reach US$ 5,286.96 million by 2033, growing at a CAGR of 6.5% during the forecast period 2025-2033.Antisense Oligonucleotides Market report, published by DataM Intelligence, provides in-depth insights and analysis on key market trends, growth opportunities, and emerging challenges. Committed to delivering actionable intelligence, DataM Intelligence empowers businesses to make informed decisions and stay ahead of the competition. Through a combination of qualitative and quantitative research methods, it offers comprehensive reports that help clients navigate complex market landscapes, drive strategic growth, and seize new opportunities in an ever-evolving global market.
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Antisense oligonucleotides (ASOs) are short, synthetic strands of nucleotides designed to bind to specific mRNA sequences, modulating gene expression. They work by blocking the translation of disease-causing proteins or promoting the degradation of faulty RNA. ASOs are used to treat genetic disorders, neurodegenerative diseases, and certain cancers, with therapies like nusinersen (Spinraza) for spinal muscular atrophy and inotersen (Tegsedi) for hereditary transthyretin amyloidosis. This precision medicine approach offers a targeted way to address previously untreatable conditions. Ongoing research aims to expand ASO applications across various therapeutic areas, including rare diseases.
List of the Key Players in the Antisense Oligonucleotides Market:
Ionis Pharmaceuticals, Inc. Sarepta Therapeutics, Alnylam Pharmaceuticals, Inc. Percheron Therapeutics, Isarna Therapeutics GmbH, Novartis AG, Jazz Pharmaceuticals, Akcea Pharma, Genzyme and Biogen among others.
Industry Development:
In January 2024, Vanda Pharmaceuticals received FDA approval for an Investigational New Drug (IND) application to evaluate VCA-894A, an antisense oligonucleotide (ASO) therapy, for the treatment of Charcot-Marie-Tooth disease, axonal, type 2S (CMT2S). This rare neuromuscular disorder is caused by cryptic splice site variants in the IGHMBP2 gene, and the investigational therapy aims to address the underlying genetic cause of the disease.
Growth Forecast Projected:
The Global Antisense Oligonucleotides Market is anticipated to rise at a considerable rate during the forecast period, between 2024 and 2031. In 2023, the market is growing at a steady rate, and with the rising adoption of strategies by key players, the market is expected to rise over the projected horizon.
Research Process:
Both primary and secondary data sources have been used in the global Antisense Oligonucleotides Market research report. During the research process, a wide range of industry-affecting factors are examined, including governmental regulations, market conditions, competitive levels, historical data, market situation, technological advancements, upcoming developments, in related businesses, as well as market volatility, prospects, potential barriers, and challenges.
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Segment Covered in the Antisense Oligonucleotides Market:
By Drug Type: Eteplirsen, Fomivirsen, Mipomersen, Defibrotide, Volanesorsen, Inclisiran, Givosiran, Nusinersen, Lumasiran, Others.
By Indication: Adult, Pediatric.
Regional Analysis for Antisense Oligonucleotides Market:
The regional analysis of the Antisense Oligonucleotides Market covers key regions including North America, Europe, Asia Pacific Middle East and Africa and South America. The North America with a focus on the U.S., Canada, and Mexico; Europe, highlighting major countries like the U.K., Germany, France, and Italy, along with other nations in the region; Asia-Pacific, covering India, China, Japan, South Korea, and Australia, among others; South America, with emphasis on Colombia, Brazil, and Argentina; and the Middle East & Africa, which includes Saudi Arabia, the U.A.E., South Africa, and other countries. This comprehensive regional breakdown helps identify unique market trends and growth opportunities specific to each area.
⇥ North America (U.S., Canada, Mexico)
⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)
⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)
⇥ South America (Colombia, Brazil, Argentina, Rest of South America)
⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)
Benefits of the Report:
âž¡ A descriptive analysis of demand-supply gap, market size estimation, SWOT analysis, PESTEL Analysis and forecast in the global market.
âž¡ Top-down and bottom-up approach for regional analysis
âž¡ Porter's five forces model gives an in-depth analysis of buyers and suppliers, threats of new entrants & substitutes and competition amongst the key market players.
âž¡ By understanding the value chain analysis, the stakeholders can get a clear and detailed picture of this Market
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People Also Ask:
âž What is the global sales, production, consumption, import, and export value of the Antisense Oligonucleotides market?
âž Who are the leading manufacturers in the global Antisense Oligonucleotides industry? What is their operational status in terms of capacity, production, sales, pricing, costs, gross margin, and revenue?
âž What opportunities and challenges do vendors in the global Antisense Oligonucleotides industry face?
âž Which applications, end-users, or product types are expected to see growth? What is the market share for each type and application?
âž What are the key factors and limitations affecting the growth of the Antisense Oligonucleotides market?
âž What are the various sales, marketing, and distribution channels in the global industry?
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