Press release
Homozygous Familial Hypercholesterolemia Market to Witness Substantial Growth by 2031 | AstraZeneca, Viatris Inc., Teva Pharmaceutical Industries Ltd.
Global Homozygous Familial Hypercholesterolemia Market reached US$ 83.7 million in 2022 and is expected to reach US$ 101.8 million by 2030 growing with a CAGR of 2.5% during the forecast period 2023-2030.Homozygous Familial Hypercholesterolemia Market report, published by DataM Intelligence, provides in-depth insights and analysis on key market trends, growth opportunities, and emerging challenges. Committed to delivering actionable intelligence, DataM Intelligence empowers businesses to make informed decisions and stay ahead of the competition. Through a combination of qualitative and quantitative research methods, it offers comprehensive reports that help clients navigate complex market landscapes, drive strategic growth, and seize new opportunities in an ever-evolving global market.
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Homozygous Familial Hypercholesterolemia (HoFH) is a rare, inherited disorder characterized by extremely high levels of low-density lipoprotein (LDL) cholesterol from birth. It results from mutations in both copies of the LDL receptor gene, leading to impaired cholesterol clearance and a high risk of early-onset cardiovascular disease, including heart attacks and aortic stenosis. Symptoms may include xanthomas (cholesterol deposits in the skin and tendons) and corneal arcus (cholesterol buildup in the eyes). Treatment involves aggressive lipid-lowering therapies such as statins, PCSK9 inhibitors, LDL apheresis, and, in severe cases, liver transplantation.
List of the Key Players in the Homozygous Familial Hypercholesterolemia Market:
AstraZeneca, Viatris Inc., Teva Pharmaceutical Industries Ltd., Accord Healthcare, Changzhou Pharmaceutical Factory, Regeneron Pharmaceuticals, Inc., Amryt Pharma plc, Amgen Inc., Organon, Global Inc., CMP Pharma
Industry Development:
On September 20, 2021, the FDA granted accelerated approval to tisotumab vedotin-tftv (Tivdak, Seagen Inc.), a tissue factor-directed antibody-drug conjugate, for adults with recurrent or metastatic cervical cancer that progressed during or after chemotherapy.
On October 13, 2021, Merck announced FDA approval of KEYTRUDA, its anti-PD-1 therapy, in combination with chemotherapy, with or without bevacizumab, for treating persistent, recurrent, or metastatic cervical cancer in patients whose tumors express PD-L1 (CPS ≥1) as determined by an FDA-approved test.
Growth Forecast Projected:
The Global Homozygous Familial Hypercholesterolemia Market is anticipated to rise at a considerable rate during the forecast period, between 2024 and 2031. In 2023, the market is growing at a steady rate, and with the rising adoption of strategies by key players, the market is expected to rise over the projected horizon.
Research Process:
Both primary and secondary data sources have been used in the global Homozygous Familial Hypercholesterolemia Market research report. During the research process, a wide range of industry-affecting factors are examined, including governmental regulations, market conditions, competitive levels, historical data, market situation, technological advancements, upcoming developments, in related businesses, as well as market volatility, prospects, potential barriers, and challenges.
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Segment Covered in the Homozygous Familial Hypercholesterolemia Market:
By Drug Class: Statins, Cholesterol Absorption Inhibitors, PCSK9 Inhibitors, MTP Inhibitors, ANGPTL3 Inhibitors
By Route of Administration: Oral, Parenteral, Nasal, By Technology, CRISPR-Cas9, RNA Interference, Nanoparticle-Based Therapies
By Distribution Channel: Hospitals, Retail Pharmacies, Online Pharmacies
Regional Analysis for Homozygous Familial Hypercholesterolemia Market:
The regional analysis of the Homozygous Familial Hypercholesterolemia Market covers key regions including North America, Europe, Asia Pacific Middle East and Africa and South America. The North America with a focus on the U.S., Canada, and Mexico; Europe, highlighting major countries like the U.K., Germany, France, and Italy, along with other nations in the region; Asia-Pacific, covering India, China, Japan, South Korea, and Australia, among others; South America, with emphasis on Colombia, Brazil, and Argentina; and the Middle East & Africa, which includes Saudi Arabia, the U.A.E., South Africa, and other countries. This comprehensive regional breakdown helps identify unique market trends and growth opportunities specific to each area.
⇥ North America (U.S., Canada, Mexico)
⇥ Europe (U.K., Italy, Germany, Russia, France, Spain, The Netherlands and Rest of Europe)
⇥ Asia-Pacific (India, Japan, China, South Korea, Australia, Indonesia Rest of Asia Pacific)
⇥ South America (Colombia, Brazil, Argentina, Rest of South America)
⇥ Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of Middle East & Africa)
Benefits of the Report:
➡ A descriptive analysis of demand-supply gap, market size estimation, SWOT analysis, PESTEL Analysis and forecast in the global market.
➡ Top-down and bottom-up approach for regional analysis
➡ Porter's five forces model gives an in-depth analysis of buyers and suppliers, threats of new entrants & substitutes and competition amongst the key market players.
➡ By understanding the value chain analysis, the stakeholders can get a clear and detailed picture of this Market
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People Also Ask:
➠ What is the global sales, production, consumption, import, and export value of the Homozygous Familial Hypercholesterolemia market?
➠ Who are the leading manufacturers in the global Homozygous Familial Hypercholesterolemia industry? What is their operational status in terms of capacity, production, sales, pricing, costs, gross margin, and revenue?
➠ What opportunities and challenges do vendors in the global Homozygous Familial Hypercholesterolemia industry face?
➠ Which applications, end-users, or product types are expected to see growth? What is the market share for each type and application?
➠ What are the key factors and limitations affecting the growth of the Homozygous Familial Hypercholesterolemia market?
➠ What are the various sales, marketing, and distribution channels in the global industry?
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Introduction
Homozygous Familial Hypercholesterolemia (HoFH) is a rare genetic lipid disorder characterized by extremely high low-density lipoprotein cholesterol (LDL-C) levels from birth, often exceeding 500 mg/dL. Caused by mutations in both alleles of the LDLR, APOB, or PCSK9 genes, HoFH leads to early-onset atherosclerosis, cardiovascular disease, and premature mortality if untreated.
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