Oligonucleotide Therapy Market Poised for 12.3 % Growth, Set to Hit $3827.78 Billion by 2029

Which drivers are expected to have the greatest impact on the over the oligonucleotide therapy market's growth?
The increase in cancer incidence globally is expected to fuel the expansion of the oligonucleotide therapy market in the upcoming years. For instance, according to the American Cancer Society's report in January 2022, the US will potentially witness 1.9 million fresh cancer cases and approximately 609,360 cancer-associated deaths, translating to about 1,670 deaths daily. Lung, prostate, bowel, and female breast cancer are the four most prevalent types of cancers globally, representing 43% of all new cancer diagnoses. Consequently, the growing rates of cancer worldwide are likely to stimulate the demand for the oligonucleotide therapy market in the near future.

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What Is the projected market size and growth rate for the oligonucleotide therapy market?
The market size for oligonucleotide therapy has experienced rapid expansion in the past few years. It's forecasted to surge from $5.55 billion in 2024 to $6.18 billion in 2025, reflecting a compound annual growth rate (CAGR) of 11.4%. The significant growth in the historic period can be credited to an increase in research and development investments, the introduction of early therapies, emergence of gene editing methods, earlier therapeutic findings, and the introduction of RNAi and antisense oligonucleotide.

In the coming years, the size of the oligonucleotide therapy market is anticipated to experience swift expansion. It is predicted to magnify to $9.82 billion by 2029 with a compound annual growth rate (CAGR) of 12.3%. The surge in this forecast period is credited to elements such as investment in research and development, broader global market penetration, expansion in the therapeutic field, strategies for modifying diseases, and adaptive regulatory procedures. Key trends in the said period comprise personalized treatments, enhanced delivery systems, advancements in RNA interference (RNAI), antisense oligonucleotide invention, and the incorporation of gene-editing techniques.

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What are the most significant trends transforming the oligonucleotide therapy market today?
Those involved in the creation and supply of the oligonucleotide therapy market are channeling resources into research and development with the aim to improve the therapeutic design, thereby lessening its adverse effects on patients. The state-of-the-art oligonucleotides permit the application of precision medicine tactics and can be specifically engineered to target any gene with limited side consequences. This is also advantageous for homing in on patient-based sequences which are the origin of uncommon diseases. In April 2023, the FDA gave the okey for Qalsody, an antisense oligonucleotide (ASO), to be utilized in treating patients suffering from amyotrophic lateral sclerosis (ALS) linked to a mutation in the superoxide dismutase 1 (SOD1) gene. Qalsody is designed to target SOD1 mRNA to decrease the formation of SOD1 protein.

Which key market segments comprise the oligonucleotide therapy market and drive its revenue growth?
The oligonucleotide therapy market covered in this report is segmented -

1) By Type: Antisense Oligonucleotide, Aptamer, Other Types
2) By Application: Infectious Diseases, Oncology, Neurodegenerative Disorders, Cardiovascular Diseases, Kidney Diseases, Other End-User
3) By End User: Hospitals, Research Institutes

Subsegments:
1) By Antisense Oligonucleotide: RNA-Targeted Antisense Oligonucleotides, DNA-Targeted Antisense Oligonucleotides, Chemically Modified Antisense Oligonucleotides
2) By Aptamer: DNA Aptamers, RNA Aptamers, Small Molecule Aptamers
3) By Other Types: siRNA (Small Interfering RNA), miRNA (Micro RNA), DNAzyme And Ribozymes, Synthetic Oligonucleotides For Gene Editing

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What regions are at the forefront of oligonucleotide therapy market expansion?
North America was the largest region in the oligonucleotide therapy market in 2024. The regions covered in the oligonucleotide therapy market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

Who are the leading players fueling growth in the oligonucleotide therapy market?
Major companies operating in the oligonucleotide therapy market include Pfizer Inc., Merck & Co. Inc., GlaxoSmithKline plc, Gilead Sciences Inc., BioNTech SE, Moderna Inc., Biogen Inc., Jazz Pharmaceuticals plc, QIAGEN Company, Alnylam Pharmaceuticals Inc., Sarepta Therapeutics Inc., Ionis Pharmaceuticals Inc., Akcea Therapeutics Inc., Arrowhead Pharmaceuticals Inc., Dicerna Pharmaceuticals Inc., SomaGenics Inc., Wave Life Sciences Ltd., Exicure Inc., Avidity Biosciences Inc., Miragen Therapeutics Inc., ProQR Therapeutics NV, Regulus Therapeutics Inc., Kastle Therapeutics LLC, Santaris Pharma A/S, InteRNA Technologies B.V., Dynacure S.A., Arcturus Therapeutics Holdings Inc., Intellia Therapeutics Inc., Regeneron Pharmaceuticals Inc., Editas Medicine Inc., Evox Therapeutics Ltd., PepGen Ltd.

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What Is Covered In The Oligonucleotide Therapy Global Market Report?

•Market Size Forecast: Examine the oligonucleotide therapy market size across key regions, countries, product categories, and applications.
•Segmentation Insights: Identify and classify subsegments within the oligonucleotide therapy market for a structured understanding.
•Key Players Overview: Analyze major players in the oligonucleotide therapy market, including their market value, share, and competitive positioning.
•Growth Trends Exploration: Assess individual growth patterns and future opportunities in the oligonucleotide therapy market.
•Segment Contributions: Evaluate how different segments drive overall growth in the oligonucleotide therapy market.
•Growth Factors: Highlight key drivers and opportunities influencing the expansion of the oligonucleotide therapy market.
•Industry Challenges: Identify potential risks and obstacles affecting the oligonucleotide therapy market.
•Competitive Landscape: Review strategic developments in the oligonucleotide therapy market, including expansions, agreements, and new product launches.

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