Impact Of Rising Respiratory Disease Prevalence On The Alpha-1 Antitrypsin Deficiency Augmentation Therapy Market Driver: Leading Transformation in the Alpha-1 Antitrypsin Deficiency Augmentation Therapy Market in 2025

What industry-specific factors are fueling the growth of the alpha-1 antitrypsin deficiency augmentation therapy market?
The surge in respiratory diseases is fuelling the expansion of the alpha-1 antitrypsin deficiency augmentation therapy market since these complications entail adverse effects on the lungs and respiratory system, culminating to impaired lung activities and breathing challenges. The objective of the alpha-1 antitrypsin deficiency augmentation therapy is addressing respiratory ailments by providing the body with the protein it's deficient in for individuals suffering from alpha-1 antitrypsin deficiency. Its efficacy is proven by recalibrating protease-antiprotease levels in the lungs and protecting lung tissues from damages brought about by heightened neutrophil elastase activities and curbing inflammation. The Centers for Disease Control and Prevention reported in March 2023 that the US had 8,300 tuberculosis cases in 2022, an upsurge from the 7,874 cases of 2021, further emphasizing that a rise in respiratory diseases accelerates the alpha-1 antitrypsin deficiency augmentation therapy market's growth. Alpha-1 Antitrypsin Deficiency Augmentation Therapy Market Driver: The Anticipated Growth of Alpha-1 Antitrypsin Deficiency Augmentation Therapy Market Arises from an Increase in Clinical Trials

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What Is the projected market size and growth rate for the alpha-1 antitrypsin deficiency augmentation therapy market?
Recent years have seen significant growth in the market size of alpha-1 antitrypsin deficiency augmentation therapy. The market, which is expected to expand from $1.69 billion in 2024 to $1.82 billion in 2025, is predicted to have a compound annual growth rate (CAGR) of 7.3%. Contributing factors to this growth during the historic period include better diagnostic practices, awareness initiatives, clinical studies, and an aging population.

It is predicted that the alpha-1 antitrypsin deficiency augmentation therapy market will see a robust surge in size over the coming years. The market is projected to expand to a value of $2.47 billion by 2029, growing at a compound annual growth rate (CAGR) of 7.9%. This growth through the forecasted period is credited to developments in telehealth, remote monitoring, precision medicine and gene therapy. Amid the forecast period, key trends to monitor include the long-term safety and efficacy data, models of care that center on the patient, tele-rehabilitation programs and individualized dosage plans.

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What are the most significant trends transforming the alpha-1 antitrypsin deficiency augmentation therapy market today?
Leading corporations in the acute respiratory distress syndrome (ARDS) market are investing in the development of novel treatments, such as those based on recombinant technology, to maintain their market status. The method used for recombinant technology-based drug development employs recombinant DNA technology, which involves altering the DNA of live organisms to produce specific proteins. For instance, in March 2022, Inhibrx Inc., a biotech firm based in the United States, declared that the US Food and Drug Administration (FDA) has granted orphan drug status to INBRX-101 for the treatment of alpha-1 antitrypsin deficiency (AATD). INBRX-101 is a recombinant human AAT-Fc fusion protein with the capacity for once-monthly dosage, designed to safely reach and maintain AAT levels seen in healthy individuals.

What major market segments define the scope and growth of the alpha-1 antitrypsin deficiency augmentation therapy market?
The alpha-1 antitrypsin deficiency augmentation therapy market covered in this report is segmented -

1) By Product Type: Glassia, Aralast NP, Prolastin C, Zemaira And Respreeza
2) By Route Of Administration: Oral, Injection, Inhalation
3) By End User: Hospitals, Specialty Clinics, Other End Users

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Which region dominates the alpha-1 antitrypsin deficiency augmentation therapy market?
North America was the largest region in the alpha-1 antitrypsin deficiency augmentation therapy market in 2024. The regions covered in alpha-1 antitrypsin deficiency augmentation therapy market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

Which key market leaders are driving the alpha-1 antitrypsin deficiency augmentation therapy industry growth?
Major companies operating in the alpha-1 antitrypsin deficiency augmentation therapy market are Pfizer Inc., Sanofi S.A., AstraZeneca PLC, GlaxoSmithKline PLC, Takeda Pharmaceutical Company Limited, Amgen Inc., Baxter International Inc., CSL Limited, Biogen Inc., Vertex Pharmaceuticals Incorporated, Grifols S.A., BioMarin Pharmaceutical Inc., LFB Group, Octapharma AG, Arrowhead Pharmaceuticals Inc., Kamada Ltd., Krystal Biotech Inc., Intellia Therapeutics Inc., Mereo BioPharma Group PLC, Protalix BioTherapeutics Inc., Centessa Pharmaceuticals Limited, Inhibrx Inc., Liminal BioSciences Inc., Applied Genetic Technologies Corporation, Abeona Therapeutics Inc.

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What Is Covered In The Alpha-1 Antitrypsin Deficiency Augmentation Therapy Global Market Report?

• Market Size Forecast: Examine the alpha-1 antitrypsin deficiency augmentation therapy market size across key regions, countries, product categories, and applications.
• Segmentation Insights: Identify and classify subsegments within the alpha-1 antitrypsin deficiency augmentation therapy market for a structured understanding.
• Key Players Overview: Analyze major players in the alpha-1 antitrypsin deficiency augmentation therapy market, including their market value, share, and competitive positioning.
• Growth Trends Exploration: Assess individual growth patterns and future opportunities in the alpha-1 antitrypsin deficiency augmentation therapy market.
• Segment Contributions: Evaluate how different segments drive overall growth in the alpha-1 antitrypsin deficiency augmentation therapy market.
• Growth Factors: Highlight key drivers and opportunities influencing the expansion of the alpha-1 antitrypsin deficiency augmentation therapy market.
• Industry Challenges: Identify potential risks and obstacles affecting the alpha-1 antitrypsin deficiency augmentation therapy market.
• Competitive Landscape: Review strategic developments in the alpha-1 antitrypsin deficiency augmentation therapy market, including expansions, agreements, and new product launches.

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