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Global Gene Therapy Market to Reach $31.48 Billion by 2029, Growing at 17.8% CAGR

03-06-2025 12:08 PM CET | Health & Medicine

Press release from: The Business Research Company

Gene Therapy

Gene Therapy

What industry-specific factors are fueling the growth of the gene therapy market?
The escalating occurrence of cancer and a range of other diseases has spurred a demand for effective remedies, bolstering the development of the gene therapy market. The global surge in cancer incidents is predicted to augment the expansion of the gene therapy market within the forecasted period. For example, as stated by the American Cancer Society in January 2022, the US is predicted to have approximately 1.9 million fresh cancer diagnoses and 609,360 cancer-induced fatalities, averaging 1,670 deaths daily. Lung, prostate, bowel, and female breast cancer are the four most prevalent forms worldwide, comprising 43 percent of all emerging cancer cases. As a result, the global increase in cancer rates is expected to stimulate the demand for the gene therapy market in the forthcoming years. Gene therapy, an effective treatment in oncology, involves incorporating new genes into malignant or nearby cells to induce cell death or decelerate cancer growth.

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What Is the projected market size and growth rate for the gene therapy market?
The size of the gene therapy market has seen massive expansion in the past few years. Its growth is projected to increase from $12.52 billion in 2024 to $16.36 billion in 2025, reflecting a compound annual growth rate (CAGR) of 30.7%. Factors contributing to this upswing during the historic period include an increase in pharmaceutical R&D spending, growth in public-private collaborations, government funding and a surge in instances of spinal muscular atrophy.

The size of the gene therapy market is projected to experience substantial expansion in the coming years, reaching a value of $31.48 billion by 2029 with a compound annual growth rate (CAGR) of 17.8%. This predicted surge within the forecast period is due to factors such as the escalating number of cancer cases, an increasing elderly population, increased investment in research and development within the pharmaceutical sector, and an intensified focus on gene therapy. Dominant trends predicted for this period encompass achieving enhanced business operations by obtaining regulatory approvals, reinforcing business activities through strategic collaborations and partnerships, growing business capacity through strategic acquisitions, and solidifying operational abilities via business expansion.

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What new trends are reshaping the gene therapy market and its opportunities?
The gene therapy market is progressively seeing an increase in the application of machine learning and artificial intelligence (AI). AI refers to the replication of human intelligence processes by machines, specifically through self-learning algorithms. Machine learning is a component of AI. These technologies assist businesses in the gene therapy market to thoroughly analyze comprehensive data, discern relationships between tumor and immune cells, and provide a more precise evaluation of tissue samples. An instance of this was in May 2023, when Form Bio, an American company specializing in life-science software, produced FORMsightAI. This advanced AI-based solution set predicts and optimizes manufacturing outcomes of cell and gene therapy constructs. FORMsightAI merges dynamic AI models with Form Bio's basic platform, supported by a proficient team of computational life sciences professionals with experience in biology, bioinformatics, and data science. The solution tackles frequent challenges encountered by cell and gene therapy developers such as construct truncations and manufacturing contaminations. These issues are primary contributors to low manufacturing yields, delays in market entry, and problems with therapeutic safety.

What major market segments define the scope and growth of the gene therapy market?
The gene therapy market covered in this report is segmented -

1) By Gene Therapy Type: Germline Therapy, Somatic Cell Therapy
2) By Vector: Viral Vector, Non-Viral Vector
3) By Application: Oncology, Orphan Disease, Knee Osteoarthritis, Neurological Disorders
4) By End Users: Biopharmaceutical Companies, Research Institutes, Other End Users

Subsegments:
1) By Germline Therapy: Inherited Disease Treatment, Genetic Modification Of Embryos, Gene Editing Techniques, Ethical And Regulatory Considerations
2) By Somatic Cell Therapy: Cancer Gene Therapy, Monogenic Disorder Treatment, Gene Replacement Therapy, RNA-Based Therapies, Gene Editing Techniques

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Which region dominates the gene therapy market?
North America was the largest region in the gene therapy market in 2024. The regions covered in the gene therapy market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

Which key market leaders are driving the gene therapy industry growth?
Major companies operating in the gene therapy market include UniQure NV, REGENXBIO Inc., Bristol-Myers Squibb, BioMarin Pharmaceuticals Inc., Jazz Pharmaceuticals Inc., Biocon, Cipla, EdiGene Inc, Takeda Pharmaceutical, Daiichi Sankyo Company, Mitsubishi Tanabe Pharma, Merck, GE Healthcare, Lonza, Pfizer, Cellular Biomedicine Group, GenScript, Albumedix Ltd, Catalent, Freeline Therapeutics, DiNAQOR AG, Vivet Therapeutics, Allergan, Amgen, Biocad, Celgene Corporation, Johnson & Johnson, Eli Lilly and Company, AstraZeneca, Bayer AG, Juno Therapeutics, Allogene Therapeutics, Bluebird Bio, Regen BioPharma, Bellicum, Biotchpharma, BrainStorm Cell Therapeutics, Pluristem, Sanofi

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What Is Covered In The Gene Therapy Global Market Report?

• Market Size Forecast: Examine the gene therapy market size across key regions, countries, product categories, and applications.
• Segmentation Insights: Identify and classify subsegments within the gene therapy market for a structured understanding.
• Key Players Overview: Analyze major players in the gene therapy market, including their market value, share, and competitive positioning.
• Growth Trends Exploration: Assess individual growth patterns and future opportunities in the gene therapy market.
• Segment Contributions: Evaluate how different segments drive overall growth in the gene therapy market.
• Growth Factors: Highlight key drivers and opportunities influencing the expansion of the gene therapy market.
• Industry Challenges: Identify potential risks and obstacles affecting the gene therapy market.
• Competitive Landscape: Review strategic developments in the gene therapy market, including expansions, agreements, and new product launches.

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