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In-Depth Analysis of the Downstream Processing Market: Growth Opportunities, Key Trends, and Forecast 2025-2034

03-03-2025 10:39 AM CET | Health & Medicine

Press release from: The Business Research Company

Downstream Processing Market

Downstream Processing Market

What combination of drivers is leading to accelerated growth in the downstream processing market?
The downstream processing market stands to benefit from the rise in healthcare spending. Healthcare spending encompasses all costs associated with health services, family planning programs, nutrition initiatives, and medical emergency aid. This increase in expenditure can spur sales in downstream processing because it facilitates the extraction of a drug substance (DS) from natural origins, be it bacterial or animal cells, followed by the purification of the DS. For instance, the National Health Expenditure (NHE) report for 2021-2030, released by the Centers for Medicare & Medicaid Services, a division of the US Department of Health and Human Services, foresees an average annual boost in national health spending of 5.1% between 2021 and 2030, reaching an estimated total of $6.8 trillion by 2030. Furthermore, Medicare outlays are projected to rise at a yearly average of 7.2%, whereas Medicaid spending is forecasted to see a 5.6% annual increase throughout the 2021-2030 period. Hence, the surge in healthcare costs is fueling the growth of the downstream processing market.

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What is the projected compound annual growth rate (CAGR) of the downstream processing market from 2025 to 2034, and what factors influence it?
In recent times, there's been a significant expansion in the downstream processing market size. This market is projected to rise from $31.26 billion in 2024 to $35.54 billion in 2025, boasting a compound annual growth rate (CAGR) of 13.7%. Factors contributing to the growth during the historic period encompass increased investment in biopharmaceuticals, strict regulatory standards, the global spread of biopharmaceutical production, and a higher prevalence of chronic diseases.

In the forthcoming years, the downstream processing market is projected to experience a significant expansion. The market is predicted to reach a value of "$58.96 billion by 2029, with a compound annual growth rate (CAGR) of 13.5%. This projected growth can be accredited to factors such as the heightened demand for biopharmaceuticals, an emphasis on sustainable and green processing, collaborations and partnerships, and the adoption of continuous bioprocessing. The rising demand for personalized medications is also a key contributor. The forecast period will witness major trends such as the integration of digitalization and industry 4.0, technological progress, the use of single-use systems, growth in the biopharmaceutical industry, and the rise in continuous processing.

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How are the latest trends influencing the growth of the downstream processing market?
The downstream processing market sees key trends in product innovations. A lot of leading organizations in this sector are focusing on inventing new technological tools to solidify their footing in the market. Such is the case with Tosoh Bioscience LLC, a specialty materials and global chemical company based in the USA, that initiated the Octave BIO Multi-Column Chromatography (MCC) system in September 2022. This comprehensive MCC system, designed for intensifying biomolecule purification processes, is a novel development for process intensification in downstream processing. The unique modular design can handle a variety of needs, and offers benefits like savings on MCC's resin and buffer costs among others.

What are the major segments of the downstream processing market and their role in driving growth?
The downstream processing market covered in this report is segmented -

1) By Product: Centrifuges, Dryers, Chromatography Systems, Filters, Evaporators, Other Products
2) By Technique: Purification Techniques, Solid-Liquid Separation, Clarification Or Concentration
3) By Application: Monoclonal Antibody Production, Vaccine Production, Insulin Production, Immunoglobulin Production, Erythropoietin Production, Other Applications

Subsegments:
1) By Centrifuges: Analytical Centrifuges, Preparative Centrifuges
2) By Dryers: Spray Dryers, Freeze Dryers, Fluidized Bed Dryers
3) By Chromatography Systems: Liquid Chromatography Systems, Gas Chromatography Systems, Affinity Chromatography Systems
4) By Filters: Membrane Filters, Depth Filters, Cartridge Filters
5) By Evaporators: Thin Film Evaporators, Forced Circulation Evaporators, Falling Film Evaporators
6) By Other Products: Mixers, Precipitation Systems, Storage Tanks

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Which regions are key players in the growth of the downstream processing market?
North America was the largest region in the downstream processing market in 2024.Asia-Pacific is expected to be the fastest-growing region in the global downstream processing market report during the forecast period. The regions covered in the downstream processing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

Who are the key firms paving the way for growth in the downstream processing market?
Major companies operating in the downstream processing market include Sartorius AG, General Electric Company, Merck KGaA, Thermo Fisher Scientific Inc., Danaher Corporation, Repligen Corporation, Lonza Group Ltd., Eppendorf AG, Corning Corporation, Ashai Kasei Corporation, Finesse Solutions Inc., MilliporeSigma, Pall Corporation, Bio-Rad Laboratories, Charles River Laboratories International Inc., Waters Corporation, Becton Dickinson and Company (BD), Entegris Inc., Novasep, Avantor Sciences, Tecan Group, Agilent Technologies, Boehringer Ingelheim International GmbH, Ahlstrom-Munksjö Oyj, Grifols S.A., GenScript Biotech Corporation

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What Is Covered In The Downstream Processing Global Market Report?

• Market Size Forecast: Examine the downstream processing market size across key regions, countries, product categories, and applications.
• Segmentation Insights: Identify and classify subsegments within the downstream processing market for a structured understanding.
• Key Players Overview: Analyze major players in the downstream processing market, including their market value, share, and competitive positioning.
• Growth Trends Exploration: Assess individual growth patterns and future opportunities in the downstream processing market.
• Segment Contributions: Evaluate how different segments drive overall growth in the downstream processing market.
• Growth Factors: Highlight key drivers and opportunities influencing the expansion of the downstream processing market.
• Industry Challenges: Identify potential risks and obstacles affecting the downstream processing market.
• Competitive Landscape: Review strategic developments in the downstream processing market, including expansions, agreements, and new product launches.

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