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Key Trends Shaping the Future Pyrogen Testing Market From 2025-2034: Animal-Free Pyrogen Testing With Pyrodetect And Pyromat Mat Systems

02-25-2025 10:44 AM CET | Industry, Real Estate & Construction

Press release from: The Business Research Company

Pyrogen Testing Market Forecast

Pyrogen Testing Market Forecast

Which drivers are expected to have the greatest impact on the over the pyrogen testing market's growth?
The escalating investments in the research and development sector of the pharmaceutical and biotech industries are bolstering the growth of the pyrogen testing market. This type of testing is adopted by pharmaceutical, biotech, and various drug manufacturing businesses to ensure the production and release of products that are free from infection. For instance, the Association of the British Pharmaceutical Industry, a trade association based in the UK, revealed in 2022 that the innovative pharmaceutical industry has infused about £9 billion into UK research and development (R&D). This has the possibility to propel both the nation's health and economy. Consequently, the extensive investments made by pharmaceutical firms in research and development are propelling the pyrogen testing market.

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What is the future CAGR of the pyrogen testing market, and how will it impact industry expansion?
In the last few years, the pyrogen testing market has expanded dramatically. It is projected to increase from $1.68 billion in 2024 to $1.91 billion in 2025, with a compound annual growth rate (CAGR) of 13.8%. The augmentation during the historic period can be linked to the expansion of the pharmaceutical and biotechnology sector, drug safety regulations, advances in test procedures, an upsurge in infectious disease outbreaks, and utilization in medical device manufacturing.

The pyrogen testing market is predicted to experience a fast-paced expansion in the coming years, with its market size expected to reach $3.1 billion by 2029, growing at a compound annual growth rate (CAGR) of 12.8%. Factors such as tailored pyrogen testing solutions, the rise of rapid and automated testing methods, breakthroughs in in vitro pyrogen detection, and the embracing of pyrogen testing in cell therapy and sustainable, environmental testing practices, have all contributed to this predicted growth. Foreseen trends for the forecast period include adoption of point-of-care pyrogen testing, maintaining regulatory compliance in pyrogen testing, the integration of artificial intelligence in pyrogen detection and analysis, the development of personalized and patient-specific pyrogen testing, and the emphasis on transparency and traceability in testing procedures.

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What are the most significant trends transforming the pyrogen testing market today?
Firms are prioritizing the development of numerous animal-independent pyrogen testing techniques, such as monocyte activation assay (MAT), to navigate the limitations of the rabbit pyrogen testing method and LAL test, thereby fostering a more humane treatment of animals. The MAT method offers an elevated level of pyrogenic activity prediction while enhancing the simulation of the fever response better than the RPT or BET/LAL. The MAT technique is employed for identifying both endotoxin and non-endotoxin pyrogens, contrasting with the LAL test which can only detect endotoxin pyrogen. Take Merck for example, they concentrated on two MAT systems for pyrogen detection, these are PyroDetect and PyroMAT.

Which key market segments comprise the pyrogen testing market and drive its revenue growth?
The pyrogen testing market covered in this report is segmented -

1) By Test Type: LAL Test, In Vitro Test, Rabbit Test
2) By Product And Service: Assays, Kits, And Reagents, Instruments, Services
3) By Application: Pharmaceutical And Biologics, Medical Devices, Other Applications

Subsegments:
1) By Test Limulus Amebocyte Lysate (LAL) Test: Gel Clot LAL Test, Chromogenic LAL Test, Turbidimetric LAL Test
2) By In Vitro Test: Monocyte Activation Test (MAT), Recombinant Factor C (rFC) Assay, Other In Vitro Tests
3) By Rabbit Test: Pyrogen Test in Rabbits, Other Animal-Based Tests

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What regions are at the forefront of pyrogen testing market expansion?
North America was the largest region in the pyrogen testing market in 2024. Asia-Pacific is expected to continue to be the fastest growing region in the pyrogen testing market share during the forecast period. The regions covered in the pyrogen testing market report include Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

Who are the leading players fueling growth in the pyrogen testing market?
Major companies operating in the pyrogen testing market include Thermo Fisher Scientific Inc., Merck KGaA, Charles River Laboratories Inc., Lonza Group Ltd., Ellab A/S, Nelson Laboratories LLC, Associates of Cape Cod Inc., GenScript Biotech Corporation, bioMérieux SA, Hyglos GmbH, Sanquin Blood Supply Foundation, Wako Chemicals USA Inc., Pyrostar International Inc., Eurofins Scientific SE, SGS SA, WuXi AppTec Group, Sigma-Aldrich Co. LLC, Bio-Rad Laboratories Inc., Microcoat Biotechnologie GmbH, Sartorius AG, Pacific Biolabs Inc., Toxikon Corporation, STERIS Corporation, Avance Biosciences Inc., BioReliance Corporation, Microbiological Consulting LLC, Microbac Laboratories Inc., North American Science Associates Inc., Pace Analytical Life Sciences LLC

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What Is Covered In The Pyrogen Testing Global Market Report?

•Market Size Forecast: Examine the pyrogen testing market size across key regions, countries, product categories, and applications.
•Segmentation Insights: Identify and classify subsegments within the pyrogen testing market for a structured understanding.
•Key Players Overview: Analyze major players in the pyrogen testing market, including their market value, share, and competitive positioning.
•Growth Trends Exploration: Assess individual growth patterns and future opportunities in the pyrogen testing market.
•Segment Contributions: Evaluate how different segments drive overall growth in the pyrogen testing market.
•Growth Factors: Highlight key drivers and opportunities influencing the expansion of the pyrogen testing market.
•Industry Challenges: Identify potential risks and obstacles affecting the pyrogen testing market.
•Competitive Landscape: Review strategic developments in the pyrogen testing market, including expansions, agreements, and new product launches.

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With over 15,000+ reports from 27 industries covering 60+ geographies, The Business Research Company has built a reputation for offering comprehensive, data-rich research and insights. Our flagship product, the Global Market Model delivers comprehensive and updated forecasts to support informed decision-making.

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