Hypertrophic Cardiomyopathy Treatment Market 2034: Clinical Trials, EMA, PDMA, FDA Approvals, Medication, Patient Pool, MOA, ROA and Companies by DelveInsight

Hypertrophic Cardiomyopathy Companies are Edgewise Therapeutics, Inc., Lexicon Pharmaceuticals, Shandong Suncadia Medicine, Ji Xing Pharmaceuticals, Rocket Pharmaceuticals, Bristol-Myers Squibb, Novartis, Gilead Sciences, Cytokinetics, Imbria Pharmaceuticals, MyoKardia, Inc., Cytokinetics, Tenaya Therapeutics, Novartis, and others.
(Albany, UJSA) DelveInsight's "Hypertrophic Cardiomyopathy Market Insights, Epidemiology and Market Forecast 2034" report delivers an in-depth understanding of the Hypertrophic Cardiomyopathy, historical and forecasted epidemiology as well as the Hypertrophic Cardiomyopathy market trends in the United States, EU4 (Germany, Spain, Italy, and France) and the United Kingdom, and Japan.

Hypertrophic Cardiomyopathy Treatment Market is projected to witness substantial growth over the next few years, driven by advancements in treatment modalities and increasing awareness of the condition. The pipeline for Hypertrophic Cardiomyopathy Therapeutics includes promising candidates that aim to not only treat acute attacks but also prevent recurrence.

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Key Takeaways from the Hypertrophic Cardiomyopathy Market Report

* The Hypertrophic Cardiomyopathy market size was valued ~USD 646 million in 2023 and is anticipated to grow with a significant CAGR of 20% during the study period (2020-2034)
* In December 2024, Tenaya Therapeutics, Inc. (NASDAQ: TNYA), a clinical-stage biotechnology company focused on discovering, developing, and delivering potentially curative therapies for heart disease, has announced promising early results from the first cohort of patients in the MyPEAK-1 clinical trial of TN-201 gene therapy. TN-201 is being developed as a potential treatment for MYBPC3-associated hypertrophic cardiomyopathy (HCM), a condition caused by inadequate levels of myosin-binding protein C (MyBP-C).
* In September 2024, Edgewise Therapeutics reported promising top-line results from two clinical trials evaluating EDG-7500 as a potential treatment for obstructive hypertrophic cardiomyopathy (HCM). The findings include data from a Phase I trial in healthy participants and the single-dose arm of the Phase II CIRRUS-HCM trial. EDG-7500, an oral and selective modulator, is specifically designed to target cardiac relaxation challenges associated with HCM.
* In April 2024, Imbria Pharmaceuticals, Inc., a clinical-stage cardiometabolic company focused on developing innovative therapies to enhance patient symptoms and functional capacity by improving cellular energetics, announced that findings from the Phase 2 IMPROVE-HCM clinical trial investigating ninerafaxstat in patients with symptomatic nHCM were unveiled during a late-breaking clinical trial session at the American College of Cardiology's Annual Scientific Session & Expo (ACC.24) and published in the Journal of the American College of Cardiology (JACC).
* As per DelveInsight's assessments, males are more affected by HCM than females. Also, the cases are projected to increase by 2034 in the United States.
* As per assessments by DelveInsight analysts, there were nearly 2,887 diagnosed prevalent cases of Obstructive HCM (HOCM), and 1,443 diagnosed prevalent cases of Non-obstructive HCM (HNCM) in 2023 in Japan.
* In the assessment done by DelveInsight, the estimated total diagnosed prevalent cases of HCM in the 7MM was 246,272 in 2023. The highest diagnosed prevalent cases of HCM were accounted by the US for 48% in 2022 which were approximately of the 7MM. These cases are expected to increase during the forecast period (2023-2034).
* Key Hypertrophic Cardiomyopathy Companies: Edgewise Therapeutics, Inc., Lexicon Pharmaceuticals, Shandong Suncadia Medicine, Ji Xing Pharmaceuticals, Rocket Pharmaceuticals, Bristol-Myers Squibb, Novartis, Gilead Sciences, Cytokinetics, Imbria Pharmaceuticals, MyoKardia, Inc., Cytokinetics, Tenaya Therapeutics, Novartis, and others
* Key Hypertrophic Cardiomyopathy Therapies: EDG-7500, Sotagliflozin, HRS-1893, Aficamten, RP-A501, Mavacamten, MYK-224, LCZ696, Ranolazine, CK-3773274, IMB-1018972, MYK-461, TN-201, LCZ696, and others

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Hypertrophic Cardiomyopathy Epidemiology Segmentation in the 7MM

* Total Prevalent Cases
* Diagnosed Prevalent Cases
* Gender-specific Diagnosed Prevalent Cases
* Type-specific Diagnosed Prevalent Cases
* Total Treated Cases

Hypertrophic Cardiomyopathy Market Insights

Current pharmacological strategies for hypertrophic cardiomyopathy (HCM) focus on symptom management, particularly for obstructive HCM. Treatment primarily targets left ventricular outflow tract (LVOT) obstruction, using -adrenergic antagonists, calcium channel blockers, and antiarrhythmic drugs. "CAMZYOS (Mavacamten) is the first and only cardiac myosin inhibitor approved by the US FDA indicated for the treatment of adults with symptomatic New York Heart Association (NYHA) class II-III obstructive HCM to improve functional capacity and symptoms."

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Hypertrophic Cardiomyopathy Marketed Drugs

* Mavacamten: Bristol Myers Squibb

Mavacamten is an investigational, novel, oral, allosteric modulator of cardiac myosin; mavacamten reduces cardiac muscle contractility by inhibiting excessive myosin-actin cross-bridge formation, resulting in hypercontractility, left ventricular hypertrophy, and reduced compliance.

Hypertrophic Cardiomyopathy Emerging Drugs

* Aficamten (CK-274): Cytokinetics

Aficamten, or CK-274, is an investigational, novel, oral, small molecule cardiac myosin inhibitor discovered by company scientists independent of its collaborations for the potential treatment of hypertrophic cardiomyopathies (hypertrophic cardiomyopathy).

* MYK-224: Bristol Myers Squibb

MYK-224 is a small molecule drug that is being developed by MyoKardia, a subsidiary of Bristol-Myers Squibb, to treat diastolic heart failure (HFpEF) and obstructive hypertrophic cardiomyopathy. It is taken orally and targets the heart's cardiac myosin motor protein to normalize filling and contractility.

Hypertrophic Cardiomyopathy Market Outlook

Cardiomyopathy is a term that refers to abnormalities of heart muscle contractility, covering a heterogeneous range of etiologies. Hypertrophic cardiomyopathy is characterized by left ventricular hypertrophy and hypercontractility. It is almost always caused by mutations of genes encoding sarcomeric proteins. Current pharmacological treatment strategies of Hypertrophic cardiomyopathy are mainly centered on managing the symptoms and minimizing disease progression. However, it is important to keep in mind that these strategies are not disease-specific since they target the neurohormonal system and excitation-contraction coupling (ECC) while the basic disease mechanism remains untreated.

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Scope of the Hypertrophic Cardiomyopathy Market Report

* Coverage- 7MM
* Key Hypertrophic Cardiomyopathy Companies: Edgewise Therapeutics, Inc., Lexicon Pharmaceuticals, Shandong Suncadia Medicine, Ji Xing Pharmaceuticals, Rocket Pharmaceuticals, Bristol-Myers Squibb, Novartis, Gilead Sciences, Cytokinetics, Imbria Pharmaceuticals, MyoKardia, Inc., Cytokinetics, Tenaya Therapeutics, Novartis, and others
* Key Hypertrophic Cardiomyopathy Therapies: EDG-7500, Sotagliflozin, HRS-1893, Aficamten, RP-A501, Mavacamten, MYK-224, LCZ696, Ranolazine, CK-3773274, IMB-1018972, MYK-461, TN-201, LCZ696, and others
* Hypertrophic Cardiomyopathy Competitive Intelligence Analysis: SWOT analysis and Market entry strategies
* Hypertrophic Cardiomyopathy Unmet Needs, KOL's views, Analyst's views, Hypertrophic Cardiomyopathy Market Access and Reimbursement

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Table of Content

1 Key Insights

2 Report Introduction

3 Hypertrophic Cardiomyopathy Market Overview at a Glance

4 Epidemiology And Market Forecast Methodology

5 Executive Summary of Hypertrophic Cardiomyopathy

6 Key Events

7 Disease Background and Overview

8 Epidemiology and Patient Population

9 Patient Journey

10 Marketed Drugs

11 Emerging Products

12 Hypertrophic Cardiomyopathy: Market Analysis

13 KOL Views

14 SWOT Analysis

15 Unmet Needs

16 Reimbursement and Market Access

17 Appendix

18 Bibliography

19 Report Methodology

20 About DelveInsight

About Us

DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve.

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