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Major Market Shift in Chronic Rhinosinusitis With Nasal Polyps Industry: Advancements In Anti-IL-5 Biologics For CRSwNP Treatment

02-10-2025 06:11 AM CET | Health & Medicine

Press release from: The Business Research Company

Chronic Rhinosinusitis With Nasal Polyps Market Size

Chronic Rhinosinusitis With Nasal Polyps Market Size

What Is the Forecasted Market Size and Growth Rate for the Chronic Rhinosinusitis With Nasal Polyps Market?
In recent years, the market size for chronic rhinosinusitis with nasal polyps has witnessed substantial growth. It is predicted to increase from $4.02 billion in 2024 to $4.4 billion in 2025, at a compound annual growth rate (CAGR) of 9.3%. Factors that have led to this growth historically include a rise in incidence rates, enhanced diagnostic methods, innovative treatment techniques, increased patient awareness, and an upturn in healthcare expenditure.

The market for chronic rhinosinusitis with nasal polyps is predicted to experience robust expansion in the coming years, escalating to a value of $6.21 billion in 2029, with a compound annual growth rate (CAGR) of 9.0%. The anticipated growth within this period is linked to the development of biologic therapies, the rise of personalized medicine, technological progress, an increase in regulatory permissions, the rise of patient-centric care and observation of epidemiological trends. Key trends projected for this period involve the innovation of drug delivery systems, improved understanding of pathophysiology, clinical trials, longitudinal research, growing awareness, assimilation of care models, and the prevalence and incidence of the disease.

What Are the Key Drivers Behind the Growth of the Chronic Rhinosinusitis With Nasal Polyps Market?
The chronic rhinosinusitis with nasal polyps market is predicted to expand due to the growing occurrence of respiratory diseases. These diseases include a wide variety of conditions affecting the lungs and airways. A myriad of factors such as air pollution, smoking, climate change, infections, working environment exposure, and allergies contribute to the increase in respiratory diseases. The rise in conditions like asthma and chronic obstructive pulmonary disease (COPD) results in an increased rate of related conditions like CRSwNP. Consequently, there is a heightened demand for diagnostic tools, interventions, and treatments. For example, data from the National Center for Health Statistics (NCHS), a US health statistics agency, revealed in May 2024 that the cases of asthma in adults over 18 years in the United States escalated from 8.4% in 2021 to 8.7% in 2022. Moreover, the rate of asthma episodes in this age group also increased from 3.3% in 2021 to 3.7% in 2022. Therefore, the escalating occurrence of respiratory infections will stimulate the growth of the chronic rhinosinusitis with nasal polyps market.

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Which Businesses Are at the Forefront of Chronic Rhinosinusitis With Nasal Polyps Market Development?
Major companies operating in the chronic rhinosinusitis with nasal polyps market are Pfizer Inc., Roche Holding AG, Merck & Co Inc, Bayer AG, Sanofi SA, Bristol-Myers Squibb Company, AstraZeneca PLC, Novartis AG, GlaxoSmithKline plc, Takeda Pharmaceutical Company Limited, Medtronic plc, Boehringer Ingelheim International GmbH, Amgen Inc, Teva Pharmaceutical Industries Ltd, Regeneron Pharmaceuticals Inc, Daiichi Sankyo Company Limited, Olympus Corporation, Eisai Co Ltd, Smith & Nephew PLC, Genentech USA Inc, Mallinckrodt Pharmaceuticals, Lyra Therapeutics Inc, Sunovion Pharmaceuticals, Acclarent Inc., Optinose US Inc, SinuSys Corporation, Biohaven Pharmaceuticals

What Are the Latest Innovations in the Chronic Rhinosinusitis With Nasal Polyps Market?
Leading firms in the market for chronic rhinosinusitis with nasal polyps are exploring alternative treatment options such as anti-IL-5 biologics in an effort to enhance patient health outcomes and establish a competitive edge. Anti-IL-5 biologics are specialized therapies that alleviate eosinophilic inflammation seen in severe asthma and eosinophilic conditions, thus bettering symptom management and patient quality of life. For example, in March 2024, Optinose, an American pharmaceutical corporation specializing in the development and commercialization of groundbreaking products, was granted approval by the U.S. Food and Drug Administration (FDA) for its product XHANCE. This is a prescripted nasal spray used for the treatment of adult chronic rhinosinusitis, specifically chronic rhinosinusitis both with and without nasal polyps. The active agent in XHANCE is fluticasone propionate, a corticosteroid that diminishes inflammation in the nasal passages. A key characteristic of XHANCE is its unique Exhalation Delivery System (EDS), enabling patients to exhale into the device while administering the medication. This enhances the delivery of the medication deep into the nasal passages, effectively targeting the places where nasal polyps develop and where the sinuses drain.

How Is the Chronic Rhinosinusitis With Nasal Polyps Market Segmented?
The chronic rhinosinusitis with nasal polyps market covered in this report is segmented -

1) By Treatment: Medications, Surgical Methods
2) By Route Of Administration: Nasal, Oral, Other Routes Of Administration
3) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies

Subsegments:
1) By Medications: Corticosteroids (Nasal Sprays, Oral Steroids), Biologics (Monoclonal Antibodies Like Dupilumab), Antibiotics, Antihistamines, Leukotriene Modifiers
2) By Surgical Methods: Endoscopic Sinus Surgery (ESS), Polypectomy (Polyps Removal), Balloon Sinuplasty

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Where Is the Chronic Rhinosinusitis With Nasal Polyps Market Growth Most Prominent?
North America was the largest region in the chronic rhinosinusitis with nasal polyps market in 2023. The regions covered in the chronic rhinosinusitis with nasal polyps market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

What Is Covered In The Chronic Rhinosinusitis With Nasal Polyps Global Market Report?

- Market Size Analysis: Analyze the Chronic Rhinosinusitis With Nasal Polyps Market size by key regions, countries, product types, and applications.
- Market Segmentation Analysis: Identify various subsegments within the Chronic Rhinosinusitis With Nasal Polyps Market for effective categorization.
- Key Player Focus: Focus on key players to define their market value, share, and competitive landscape.
- Growth Trends Analysis: Examine individual growth trends and prospects in the Market.
- Market Contribution: Evaluate contributions of different segments to the overall Chronic Rhinosinusitis With Nasal Polyps Market growth.
- Growth Drivers: Detail key factors influencing market growth, including opportunities and drivers.
- Industry Challenges: Analyze challenges and risks affecting the Chronic Rhinosinusitis With Nasal Polyps Market.
- Competitive Developments: Analyze competitive developments, such as expansions, agreements, and new product launches in the market.

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