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Leading Growth Driver in the Primary Biliary Cholangitis Market in 2025: Rising Smoking Rates Fueling Growth in the Primary Biliary Cholangitis Market Driver's Influence
Primary Biliary Cholangitis Market
The primary biliary cholangitis market has grown rapidly in recent years. It will grow from $0.98 billion in 2024 to $1.09 billion in 2025, at a CAGR of 11.8%. This growth is linked to rising disease awareness, increased global healthcare spending, strategic collaborations in healthcare, advocacy for patients, and government initiatives for liver health.
The primary biliary cholangitis market is expected to reach $1.6 billion by 2029, growing at a CAGR of 9.9%. Growth is driven by advancements in biomarker research, rare disease management efforts, clinical trial collaborations, patient-centric healthcare approaches, and a rising demand for liver transplants. Key trends include biomarker advancements, non-invasive diagnostic techniques, immunomodulatory therapies, AI integration, patient-reported outcomes in clinical trials, and emerging fibrosis-targeting therapies.
What Is Contributing to the Growth of the Primary Biliary Cholangitis Market?
The rise in smoking is likely to boost the primary biliary cholangitis (PBC) market. Smoking involves inhaling and exhaling tobacco smoke, which is a known risk factor for liver diseases, including PBC. Higher smoking rates can contribute to an increase in individuals requiring medical intervention for liver-related conditions. For instance, Statistics Canada reported in July 2023 that cigarette production in Canada increased by 2.2% compared to June 2023. Additionally, cigarette sales in June rose by 2.6%, reaching 1.4 billion units compared to May. Thus, the increasing prevalence of smoking is anticipated to accelerate the growth of the primary biliary cholangitis market.
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Which Key Market Leaders Are Driving Primary Biliary Cholangitis Industry Growth?
Major companies operating in the primary biliary cholangitis market report are Pfizer Inc., F. Hoffmann-La Roche Ltd., Merck And Co. Inc., Novartis AG, Bristol-Myers Squibb Company, AstraZeneca PLC, GlaxoSmithKline PLC, Takeda Pharmaceutical Company, Amgen Inc., Boehringer Ingelheim International GmbH., Gilead Sciences Inc., Vertex Pharmaceuticals, Dr. Reddy's Laboratories Ltd., Amneal Pharmaceuticals LLC, Alnylam Pharmaceuticals Inc., Ionis Pharmaceuticals Inc., Intercept Pharmaceuticals Inc., Arrowhead Pharmaceuticals Inc., CureVac N.V., Sangamo Therapeutics Inc., Calliditas Therapeutics AB, NGM Biopharmaceuticals Inc., Bluebird Bio Inc., Intellia Therapeutics Inc., Albireo Pharma Inc., TARGET PharmaSolutions Inc., Genfit S.A., Editas Medicine Inc., CymaBay Therapeutics Inc., Ascletis Pharma Inc.
What Are the Emerging Trends in the Primary Biliary Cholangitis Industry?
Companies in the primary biliary cholangitis market are concentrating on developing specialized treatments, including orphan drugs combining obeticholic acid (OCA) and bezafibrates, to secure market exclusivity. This combination aims to offer a more effective treatment for primary biliary cholangitis (PBC), enhancing patient outcomes. For instance, in May 2023, Intercept Pharmaceuticals, Inc., a US-based biopharmaceutical company, received orphan drug designation from the FDA for the combination of obeticholic acid (OCA) and bezafibrate, a PPAR agonist. Obeticholic acid (marketed as Ocaliva) is already approved for PBC in the US, and the new combination therapy seeks to provide improved treatment options for this progressive liver disease.
What Are the Main Segments in the Primary Biliary Cholangitis Market?
The primary biliary cholangitis market covered in this report is segmented -
1) By Treatment Type: Drugs, Liver Transplantation
2) By Diagnosis: Imaging Tests, Magnetic Resonance Elastography (MRE), Magnetic Resonance Cholangiopancreatography (MRCP), Ultrasound, Fibroscan, Blood Tests, Cholesterol Test, Antibody Tests, Liver Tests, Other Diagnoses
3) By End-Users: Specialty Clinics, Homecare, Other End-Users
Subsegments:
1) By Drugs: Ursodeoxycholic Acid (UDCA), Obeticholic Acid (OCA), Fibrates, Immunosuppressive Drugs, Other Targeted Therapies
2) By Liver Transplantation: Orthotopic Liver Transplantation (OLT), Living Donor Liver Transplantation, Hepatobiliary Surgery For Liver Transplant
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Which Geographic Area Leads the Primary Biliary Cholangitis Market?
North America was the largest region in the primary biliary cholangitis market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the primary biliary cholangitis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
What Is Covered In The Primary Biliary Cholangitis Global Market Report?
- Market Size Analysis: Analyze the Primary Biliary Cholangitis Market size by key regions, countries, product types, and applications.
- Market Segmentation Analysis: Identify various subsegments within the Primary Biliary Cholangitis Market for effective categorization.
- Key Player Focus: Focus on key players to define their market value, share, and competitive landscape.
- Growth Trends Analysis: Examine individual growth trends and prospects in the Market.
- Market Contribution: Evaluate contributions of different segments to the overall Primary Biliary Cholangitis Market growth.
- Growth Drivers: Detail key factors influencing market growth, including opportunities and drivers.
- Industry Challenges: Analyze challenges and risks affecting the Primary Biliary Cholangitis Market.
- Competitive Developments: Analyze competitive developments, such as expansions, agreements, and new product launches in the market.
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