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A Deep Dive into Leukocyte Adhesion Deficiency Management Market 2025: Key Drivers, Growth Factors, and Projections 2025-2034

02-06-2025 08:05 AM CET | Health & Medicine

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Leukocyte Adhesion Deficiency Management Market Size

Leukocyte Adhesion Deficiency Management Market Size

What Are the Market Size and Growth Forecast for the Leukocyte Adhesion Deficiency Management Market?
The leukocyte adhesion deficiency management market will grow from $8.07 billion in 2024 to $8.61 billion in 2025, at a CAGR of 6.7%. Growth is attributed to increased awareness and education on the condition, advancements in genetic testing, orphan drug designations, and the global push for pediatric healthcare advancements.

The leukocyte adhesion deficiency management market will grow to $11.25 billion by 2029, driven by precision medicine, novel therapeutics, and expanded genetic testing. Trends include stem cell innovations, biomarker technologies, and telemedicine adoption.

What Is Contributing to the Growth of the Leukocyte Adhesion Deficiency Management Market?
The growing prevalence of primary immunodeficiency is anticipated to drive the expansion of the leukocyte adhesion deficiency management market. Primary immunodeficiency (PID) comprises a group of genetic disorders that compromise the immune system, making individuals more prone to infections due to defects in immune responses. Managing leukocyte adhesion deficiency aids in understanding immune system disorders and may result in better diagnostic tools and treatments for both conditions. For instance, in April 2023, data from the World Primary Immunodeficiency (WPI) Awareness Week, collected by Peace Hospital, an India-based multi-specialty hospital, revealed that primary immunodeficiency (PI) impacts an estimated 60 lakh people globally, with 70% to 90% of those affected undiagnosed. As a result, the increasing prevalence of primary immunodeficiency will propel the growth of the leukocyte adhesion deficiency management market.

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Which Key Market Leaders Are Driving Leukocyte Adhesion Deficiency Management Industry Growth?
Major companies operating in the leukocyte adhesion deficiency management market report are F. Hoffmann-La Roche Ltd., Novartis AG, GlaxoSmithKline PLC, Gilead Sciences Inc., Teva Pharmaceuticals Industries Limited, CSL Behring LLC, Vertex Pharmaceuticals Inc., Grifols International S.A., Aurobindo Pharma Ltd., BioMarin Pharmaceutical Inc., Cadila Healthcare Ltd., Ipca Laboratories Ltd., Sana Biotechnology Inc., Rocket Pharmaceuticals Inc., PT Sanbe Farma, Magenta Therapeutics Inc., Avalo Therapeutics Inc., Aspen Neuroscience Inc., Sandoz International GmbH, Orpha Labs Inc., Swiss Pharm Holding AG, Rubius Therapeutics Inc., Enochian Biosciences Inc., Sigma-Aldrich LLC, Bluebird Bio Inc.

What Are the Major Trends Shaping the Leukocyte Adhesion Deficiency Management Market?
Key companies in the leukocyte adhesion deficiency management market are advancing lentiviral vector-based gene therapies to enhance targeted treatments and improve patient outcomes. This approach involves delivering corrective genes into cells to restore immune function. For instance, in February 2024, Rocket Pharmaceuticals, a US-based biotech firm, introduced Kresladi (marnetegragene autotemcel) for treating severe leukocyte adhesion deficiency-I (LAD-I). In a Phase 1/2 trial, it showed a 100% survival rate at 12 months, significantly reducing infections and improving symptoms, offering a revolutionary treatment option in the LAD market.

What Are the Main Segments in the Leukocyte Adhesion Deficiency Management Market?
The leukocyte adhesion deficiency management market covered in this report is segmented -

1) By Treatment: Hematopoietic Stem Cell Transplantation, Recombinant Human Interferon-Gamma Treatment, Prophylactic Immunoglobulin Therapy, Antimicrobial Therapy, Prophylactic Therapy, Fucose Supplementation, Monoclonal Antibodies, Coagulation Factors
2) By Diagnosis: Blood Test, Genetic Testing, Biopsy, Other Types
3) By End-Users: Hospitals, Specialty Clinics, Other End-Users

Subsegments:
1) By Hematopoietic Stem Cell Transplantation: Related Donor Transplant, Unrelated Donor Transplant
2) By Recombinant Human Interferon-Gamma Treatment: Standard Dosing, Customized Dosing
3) By Prophylactic Immunoglobulin Therapy: Intravenous Immunoglobulin (IVIG), Subcutaneous Immunoglobulin (SCIG)
4) By Antimicrobial Therapy: Antibiotics, Antifungal Treatments
5) By Prophylactic Therapy: Vaccination Strategies, Infection Prevention Protocols
6) By Fucose Supplementation: Oral Supplements, Intravenous Supplements
7) By Monoclonal Antibodies: Specific Target Monoclonal Antibodies, Combination Therapy Monoclonal Antibodies
8) By Coagulation Factors: Factor Replacement Therapies, Novel Coagulation Agents

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Which Geographic Area Leads the Leukocyte Adhesion Deficiency Management Market?
North America was the largest region in the leukocyte adhesion deficiency management market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the leukocyte adhesion deficiency management market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

What Is Covered In The Leukocyte Adhesion Deficiency Management Global Market Report?

- Market Size Analysis: Analyze the Leukocyte Adhesion Deficiency Management Market size by key regions, countries, product types, and applications.
- Market Segmentation Analysis: Identify various subsegments within the Leukocyte Adhesion Deficiency Management Market for effective categorization.
- Key Player Focus: Focus on key players to define their market value, share, and competitive landscape.
- Growth Trends Analysis: Examine individual growth trends and prospects in the Market.
- Market Contribution: Evaluate contributions of different segments to the overall Leukocyte Adhesion Deficiency Management Market growth.
- Growth Drivers: Detail key factors influencing market growth, including opportunities and drivers.
- Industry Challenges: Analyze challenges and risks affecting the Leukocyte Adhesion Deficiency Management Market.
- Competitive Developments: Analyze competitive developments, such as expansions, agreements, and new product launches in the market.

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