Press release
The total Knee Replacement Market Growth to Accelerate in Forecast Period (2025-2035) | Zimmer Biomet , Stryker Corporation , DePuy Synthes , Smith & Nephew , Medtronic

The total Knee Replacement market accounted for USD 10.2 Billion in 2024 and is expected to reach USD 18.0 Billion by 2035, growin
The total Knee Replacement market accounted for USD 10.2 Billion in 2024 and is expected to reach USD 18.0 Billion by 2035, growing at a CAGR of around 5.3% between 2025 and 2035. The Total Knee Replacement Market is poised for significant growth shortly considering the progress made in surgical technologies, the increasing aging population, and the increasing incidences of knee diseases like osteoarthritis and rheumatoid arthritis.
The increasing use of robots in surgeries and the use of customized implants made via 3D printers are improving the accuracy of surgeries as well as patient welfare through value additions hence making new markets for the industry. Besides, knowledge about joint replacement surgeries, and better healthcare accessibility across the world especially in developing nations, are also driving factors. Nevertheless, barriers like high implant cost, low insurance coverage across certain parts of the world, and risks of complications related to surgery could slow down market advancements. Strategic sourcing is now done based on innovation, collaborations, and location since key players need to sustain competition.
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List of Companies:
• Zimmer Biomet
• Stryker Corporation
• DePuy Synthes
• Smith & Nephew
• Medtronic
• B. Braun Melsungen AG
• Conformis, Inc.
• MicroPort Scientific Corporation
• Exactech, Inc.
• Corin Group
• DJO Global
• Wright Medical Group N.V.
• Aesculap Implant Systems
• Mathys AG Bettlach
• Arthrex, Inc
Segment Analysis
Based on Procedure Type, the segment of primary knee replacement holds the largest share in the total knee replacement market because it is the first surgical option for patients with osteoarthritis or other severe conditions of the knee joint. It represents the largest procedures done across the globe thanks to increased surgical knowledge and skills, rising incidences of knee disorders, and improved sensitization among patients on the efficiency of early surgical operations. The simplicity of primary knee replacement compared to revision surgeries also makes it cheaper hence affordable to the patient its high demand by hospitals and orthopedic clinics.
Regional Analysis
Regional Analysis
North America Market occupies the largest share which has high indicators of the development of the healthcare sector, high spending on healthcare, and an increased life expectancy. Knee-related issues like osteoarthritis are more predominant in this area and hence are the drivers of knee replacement surgeries. Overall, North America has more progress using innovative instruments including robotic-based MIS surgical tools, and patient-customized implants that improve intraoperative accuracy and effectiveness of surgeries.
Competitive Landscape
The Total Knee Replacement Market is highly competitive, with key players focusing on innovation, strategic partnerships, and geographic expansion to maintain their market positions. Major companies like Zimmer Biomet, Stryker Corporation, DePuy Synthes (Johnson & Johnson), and Smith & Nephew dominate the market through their extensive product portfolios and global presence. These players are also emphasizing growth in research and development to come up with new implants including patient-specific and robotic-assisted systems to improve surgical accuracy and thus the patients' results.
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Report Coverage:
By Procedure Type
• Primary Knee Replacement
• Revision Knee Replacement
• Partial Knee Replacement
By Device Type
• Three-compartmental knee implants
• Bicompartmental knee implants
• Unicompartmental knee implants
By Implant Type
• Fixed-Bearing Implants
• Mobile-Bearing Implants
• Posterior-Stabilized Implants
• Cruciate-Retaining Implants
By Material Type
• Metal-on-Polyethylene
• Ceramic-on-Polyethylene
• Ceramic-on-Ceramic
• Metal-on-Metal
• Other
By Fixation Method
• Cemented Fixation
• Cementless Fixation
• Hybrid Fixation
By End-User
• Hospitals
• Ambulatory Surgical Centers (ASCs)
• Orthopedic Clinics
By Region
North America (US, Canada, Mexico)
Europe (U.K, France, Germany, Italy, Rest of Europe.)
Asia-Pacific (China, Japan, India, Australia, South Korea, Rest of Asia Pacific)
South America (Brazil, Argentina, Mexico, Rest of Latin America)
Middle East & Africa (GCC Countries, South Africa, Rest of Middle East & Africa)
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