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Global Inhaled Nitric Oxide Delivery Systems Market Poised for Growth Amid Rising Respiratory Disorders and Industry Collaborations
Inhaled Nitric Oxide Delivery Systems Market
A major breakthrough came in January 2023 when VERO Biotech secured USD 30 million in funding to advance its GENOSYL Delivery System, a tankless solution designed to simplify the administration of nitric oxide therapy. Innovations like this are improving patient outcomes by making treatment more efficient and accessible.
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Collaborations between companies are also leading to advancements in nitric oxide delivery across various healthcare settings, such as neonatal and acute care units. By improving ease of use and cost-effectiveness, these developments are encouraging broader adoption of iNO therapy worldwide.
Rising Prevalence of Respiratory Disorders Fuels Market Growth
Respiratory diseases, including pulmonary hypertension, neonatal respiratory distress syndrome, and chronic obstructive pulmonary disease (COPD), are major drivers of the iNO delivery systems market. According to the NCD Alliance, chronic respiratory diseases impact over 550 million adults worldwide, contributing to increased demand for effective treatments.
Studies have shown that iNO therapy significantly improves oxygenation and blood circulation in patients with respiratory distress. Its adoption is particularly high in neonatal intensive care units, where it is used to treat pulmonary hypertension in newborns. As the incidence of respiratory conditions continues to rise, healthcare providers are increasingly turning to iNO therapies as a reliable solution.
To meet this demand, companies are introducing new-generation delivery systems that enhance safety, ease of use, and treatment efficiency. These advancements are expected to further accelerate market growth in the coming years.
High Costs Remain a Key Challenge
Despite the benefits of iNO therapy, the high costs associated with delivery systems and ongoing treatment expenses pose challenges to market expansion. The equipment required for nitric oxide therapy is expensive, and maintaining a steady supply of nitric oxide gas adds to the financial burden on healthcare facilities.
Limited budgets in smaller hospitals and developing regions have restricted access to this treatment, despite its proven effectiveness. While larger medical institutions in developed countries continue to invest in advanced nitric oxide delivery systems, affordability remains a key issue for broader adoption.
Market Segmentation Insights
The Inhaled Nitric Oxide Delivery Systems market is segmented based on application into hypoxic respiratory failure (HRF), acute hypoxemic respiratory failure (AHRF), and others. In 2024, the acute hypoxemic respiratory failure (AHRF) segment leads the market due to its strong association with conditions like severe respiratory distress syndrome (ARDS) and pulmonary hypertension. iNO's ability to selectively dilate pulmonary blood vessels makes it a critical treatment option for these conditions.
Meanwhile, the hypoxic respiratory failure (HRF) segment is the fastest-growing, driven by the increasing prevalence of COPD and asthma. Ongoing research and clinical trials are further expanding the potential applications of iNO therapy, highlighting its growing role in respiratory care.
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Inhaled Nitric Oxide Delivery Systems Top Companies and Competitive Landscape
The Inhaled Nitric Oxide Delivery Systems industry is evolving with significant contributions from key players such as Mallinckrodt Pharmaceuticals, Getinge AB, VERO Biotech, Linde plc, and Beyond Air, Inc. These companies are at the forefront of developing advanced delivery systems for inhaled nitric oxide (iNO), a treatment primarily used in managing respiratory conditions such as pulmonary hypertension and acute respiratory distress syndrome (ARDS).
These systems, which deliver controlled doses of nitric oxide to patients, aim to improve oxygenation and reduce complications associated with respiratory failure. Notable developments include Mallinckrodt's INOmax EVOLVE DS system and VERO Biotech's GENOSYL Delivery System, which have enhanced the treatment landscape. As the market continues to grow, the integration of new technologies and increased funding are driving advancements in device precision and the overall effectiveness of iNO therapies.
In October 2024, Mallinckrodt announced the expanded rollout of the INOmax Evolve DS Delivery System to U.S. hospitals. The system delivers inhaled nitric oxide to treat respiratory complications in neonates, including those with pulmonary hypertension. This expansion highlights the company's focus on enhancing patient care in critical neonatal environments.
Some of the key companies in the global Inhaled Nitric Oxide Delivery Systems Market include:
Mallinckrodt Pharmaceuticals
Getinge AB
VERO Biotech
Linde plc
Beyond Air, Inc.
SLE Ltd.
Bellerophon Therapeutics
Air Liquide Healthcare
Circassia Pharmaceuticals
International Biomedical
Inhaled Nitric Oxide Delivery Systems Latest Industry Updates
In December 2023, Mallinckrodt plc received U.S. FDA clearance for its INOmax EVOLVE DS delivery system, designed to deliver INOmax (nitric oxide) gas for inhalation. The system includes a specialized injector module that tracks gas delivery waveforms, ensuring synchronized and proportional dosing of nitric oxide. It is compatible with various ventilators and respiratory care devices that are validated for use with the INOmax EVOLVE DS.
In January 2023, VERO Biotech Inc. secured USD 30 million in funding from Petrichor to support the development and commercialization of its GENOSYL Delivery System (DS), a tankless solution for inhaled nitric oxide (iNO). This investment aims to accelerate the availability of the innovative delivery system for clinical use.
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Inhaled Nitric Oxide Delivery Systems Market Segmentation Analysis
By Type Outlook (Revenue, USD Million; 2020-2033)
Paediatric
Adult
By Application Outlook (Revenue, USD Million; 2020-2033)
Hypoxic Respiratory Failure (HRF)
Acute Hypoxemic Respiratory Failure (AHRF)
Others
By Product Outlook (Revenue, USD Million; 2020-2033)
Disposables
System
By End User Outlook (Revenue, USD Million; 2020-2033)
Hospitals
Ambulatory Centers
Clinics
By Regional Outlook (Revenue, USD Million; 2020-2033)
North America
United States
Canada
Mexico
Europe
Germany
France
United Kingdom
Italy
Spain
Benelux
Rest of Europe
Asia-Pacific
China
India
Japan
South Korea
Rest of Asia-Pacific
Latin America
Brazil
Rest of Latin America
Middle East and Africa
Saudi Arabia
UAE
South Africa
Turkey
Rest of MEA
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Inhaled Nitric Oxide Delivery Systems Market Size@ https://www.emergenresearch.com/industry-report/inhaled-nitric-oxide-delivery-systems-market/market-size
Inhaled Nitric Oxide Delivery Systems Market Share@ https://www.emergenresearch.com/industry-report/inhaled-nitric-oxide-delivery-systems-market/market-share
Inhaled Nitric Oxide Delivery Systems Market Trends@ https://www.emergenresearch.com/industry-report/inhaled-nitric-oxide-delivery-systems-market/market-trends
Inhaled Nitric Oxide Delivery Systems Regional Market Demand@ https://www.emergenresearch.com/industry-report/inhaled-nitric-oxide-delivery-systems-market/regional-market-demand
Inhaled Nitric Oxide Delivery Systems Market Analysis@ https://www.emergenresearch.com/industry-report/inhaled-nitric-oxide-delivery-systems-market/market-analysis
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