Gene Synthesis Market Growth Analysis, Market Dynamics, Key Players and Innovations, Outlook and Forecast 2025-2031

The Gene Synthesis Market refers to the global industry focused on the artificial creation of DNA sequences or genes in laboratories, using chemical synthesis. This technology enables researchers and companies to design and construct genetic materials without the need for a pre-existing DNA template. Gene synthesis is an essential tool in synthetic biology, biotechnology, and genomics, facilitating advances in areas such as drug development, agriculture, and genetic engineering. Key products include synthetic DNA, oligonucleotides, and custom genes, which are used across various industries for research, therapeutics, and industrial applications.

➣ Market Size

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In 2023, the global Gene Synthesis market was valued at US$ 576 million and is projected to grow to US$ 1,661 million by 2030, registering a compound annual growth rate (CAGR) of 16.35% during the forecast period of 2024 to 2030. This robust growth reflects the increasing adoption of gene synthesis technologies across sectors like biotechnology, pharmaceuticals, and academic research.

North America accounted for a significant share of the market, valued at US$ 198.42 million in 2023, and is expected to reach US$ 477 million by 2030, with a CAGR of 13.48%.

Asia-Pacific, on the other hand, is witnessing exponential growth, increasing from US$ 209.61 million in 2023 to US$ 748.59 million by 2030, at an impressive CAGR of 19.77%.

The European market and other regions like the Middle East and South America also contribute significantly, driven by advancements in synthetic biology and growing investments in research.

North America accounted for a significant share of the market, valued at US$ 198.42 million in 2023, and is expected to reach US$ 477 million by 2030, with a CAGR of 13.48%.

Asia-Pacific, on the other hand, is witnessing exponential growth, increasing from US$ 209.61 million in 2023 to US$ 748.59 million by 2030, at an impressive CAGR of 19.77%.

The European market and other regions like the Middle East and South America also contribute significantly, driven by advancements in synthetic biology and growing investments in research.

Key statistics highlight that the market's growth trajectory is supported by the increasing demand for custom DNA synthesis, advancements in gene-editing technologies like CRISPR, and the rise in biopharmaceutical research activities globally.

Market Dynamics (Drivers, Restraints, Opportunities, and Challenges)

➣ Drivers

Rising Demand for Synthetic Biology: The growing application of synthetic biology in medicine, agriculture, and industrial biotechnology is a major driver of the gene synthesis market.

Advancements in Gene-Editing Technologies: Innovations like CRISPR-Cas9 and TALEN have increased the demand for custom gene synthesis to support gene-editing research.

Expanding Biopharmaceutical Sector: Pharmaceutical companies are leveraging synthetic genes for drug discovery and development, particularly in creating novel biologics and vaccines.

Reduction in Costs: Advances in technology and automation have significantly lowered the cost of gene synthesis, making it more accessible to researchers and industries.

➣ Restraints

Technical Complexities: Challenges related to the synthesis of long and complex DNA sequences can limit market growth.

Regulatory Hurdles: Stringent government regulations concerning synthetic biology and gene-editing research can act as barriers, especially in regions with strict bioethics frameworks.

Intellectual Property Issues: Patent-related concerns and legal disputes can hinder innovation and commercialization in the gene synthesis space.

➣ Opportunities

Expansion in Emerging Markets: Countries in Asia-Pacific, South America, and the Middle East offer untapped potential due to increasing investments in biotechnology and research.

Customized Solutions: The growing need for personalized medicine and tailored synthetic biology solutions presents lucrative opportunities for companies.

Collaboration and Partnerships: Strategic alliances between biotech firms and academic institutions can accelerate research and expand market reach.

➣ Challenges

Biosecurity Concerns: The potential misuse of gene synthesis technologies for unethical purposes poses a significant challenge for the industry.

Limited Expertise: A shortage of skilled professionals with expertise in synthetic biology can slow market expansion.

Regional Analysis

➣ North America

Market Size (2023): US$ 198.42 million

Projected Size (2030): US$ 477 million

CAGR: 13.48%

North America dominates the gene synthesis market, driven by robust research infrastructure, high adoption of advanced technologies, and significant investments in biotechnology. The presence of major companies like Thermo Scientific and GenScript also contributes to the region's leadership position.

➣ Asia-Pacific

Market Size (2023): US$ 209.61 million

Projected Size (2030): US$ 748.59 million

CAGR: 19.77%

Asia-Pacific is the fastest-growing region, with countries like China, Japan, and South Korea leading the way. Government initiatives to promote biotechnology and increasing R&D investments by academic and private institutions drive growth in this region.

Europe

Europe represents a mature market with steady growth. Key contributors include Germany, the U.K., and France, where synthetic biology research and biopharmaceutical developments are flourishing.

Rest of the World

Regions such as Latin America, the Middle East, and Africa are gradually expanding their presence in the market, with increasing focus on biotechnology research and collaborations with global players.

Competitor Analysis (in Brief)

The global gene synthesis market is highly consolidated, with the top five companies accounting for 72.41% of the market share in 2023. Key players include:

GenScript: A leading provider of gene synthesis services, focusing on custom DNA synthesis and related solutions.

Thermo Scientific: Known for its comprehensive portfolio of synthetic biology products and services.

IDT: A major player offering high-quality custom oligonucleotide synthesis.

Twist Bioscience: Renowned for its innovative silicon-based DNA synthesis platform.

Eurofins Genomics: A global provider of genomic products and services, including synthetic DNA and RNA.

Other notable companies include DNA 2.0 (ATUM), Azenta Life Sciences, and OriGene, which are investing heavily in R&D and expanding their global footprints.

Global Gene Synthesis: Market Segmentation Analysis

This report provides a deep insight into the global Gene Synthesis market, covering all its essential aspects. This ranges from a macro overview of the market to micro details of the market size, competitive landscape, development trend, niche market, key market drivers and challenges, SWOT analysis, value chain analysis, etc.

The analysis helps the reader to shape the competition within the industries and strategies for the competitive environment to enhance the potential profit. Furthermore, it provides a simple framework for evaluating and assessing the position of the business organization. The report structure also focuses on the competitive landscape of the Global Gene Synthesis market. This report introduces in detail the market share, market performance, product situation, operation situation, etc., of the main players, which helps the readers in the industry to identify the main competitors and deeply understand the competition pattern of the market.

In a word, this report is a must-read for industry players, investors, researchers, consultants, business strategists, and all those who have any kind of stake or are planning to foray into the Gene Synthesis market in any manner.

➣ Market Segmentation (by Application)
• Commercial
• Academic Research

➣ Market Segmentation (by Type)
• Below 1000 bp
• 1001-3000 bp
• 3001-5000 bp
• Above 5000 bp

➣ Key Company
• GenScript
• Thermo Scientific
• IDT
• Eurofins Genomics
• DNA 2.0 (ATUM)
• BBI
• Azenta Life Sciences
• SBS Genetech
• Bio Basic
• Twist Bioscience
• OriGene

➣ North America
• United States
• Canada
• Mexico

➣ Asia-Pacific
• China
• Japan
• South Korea
• Southeast Asia
• India
• Rest of Asia

➣ Europe
• Germany
• France
• U.K.
• Italy
• Russia
• Rest of Europe

➣ South America
• Brazil
• Rest of South America

➣ Middle East & Africa
• Middle East
• Africa

➣ Middle East & Africa
• Middle East
• Africa

➣ FAQ

➣ What is the current market size of the Gene Synthesis market?

▶ The global Gene Synthesis market was valued at US$ 576 million in 2023 and is projected to reach US$ 1,661 million by 2030.

➣ Which are the key companies operating in the Gene Synthesis market?

▶ Major companies include GenScript, Thermo Scientific, IDT, Eurofins Genomics, and Twist Bioscience.

➣ What are the key growth drivers in the Gene Synthesis market?

▶ The market is driven by rising demand for synthetic biology, advancements in gene-editing technologies, and increasing investments in biopharmaceutical research.

➣ Which regions dominate the Gene Synthesis market?

▶ North America and Asia-Pacific are the leading regions, with significant contributions from the United States, China, and Japan.

➣ What are the emerging trends in the Gene Synthesis market?

▶ Emerging trends include the increasing adoption of personalized medicine, advancements in automation technologies, and collaborations between academia and industry players.

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