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Protein Expression Market Analysis and Forecast: Segments, Applications, and Leading Players.

01-27-2025 08:09 AM CET | Health & Medicine

Press release from: Insightace Analytic Pvt Ltd.

Protein Expression Market

Protein Expression Market

InsightAce Analytic Pvt. Ltd. announces the release of a market assessment report on the "Protein Expression Market"-, By Type of Protein Expression System (Algal, Cell-free, Insect, Mammalian, Prokaryotic and Yeast), Protein Expression-related Offerings (Competent Cells, Expression Vectors, Instruments, Kits and Reagents, and Protein Expression Services), Application Area (Research and Diagnostics, and Therapeutics), End-users (Academic and Research Institutes, CROs and CDMOs, Pharmaceutical / Biotechnology Companies, and Other End-users), Type of Operation (In-house and Outsourced Operations), Industry Trends, and Global Forecasts, 2024-2031 And Segment Revenue and Forecast To 2031."

The Protein Expression Market is estimated to reach over USD 4.6 billion by 2031, exhibiting a CAGR of 7.7% during the forecast period.

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Protein expression refers to the process by which proteins are produced, regulated, and modified within living organisms, utilizing competent cells, chemicals, tools, services, and expression vectors. The protocol for protein expression is heavily reliant on reagents, which are expected to hold the largest market share due to the significant volumes required in bio-experiments. The protein expression market is poised for substantial growth, driven by increased funding from government and non-government organizations for protein research, the rising prevalence of chronic diseases, and the expansion of the life science sector. Additionally, the growing demand for protein biologics and the increased incidence of chronic disorders are expected to further propel the market's expansion during the forecast period.

The rise of contract research organizations (CROs) and contract development and manufacturing organizations (CDMOs) has created opportunities for businesses to outsource protein production, enabling them to focus on other areas of development. Innovations in expression systems, such as plant-based or yeast systems, provide alternative and more sustainable methods for producing complex proteins efficiently. With the increasing number of biologics and biosimilars, there is a growing demand for efficient protein expression systems to support the development of therapeutic proteins, including monoclonal antibodies and vaccines. Government and private sector funding for protein research, biotechnology advancements, and drug development are driving the demand for protein expression technologies. This investment supports both academic research and commercial-scale production.

List of Prominent Players in the Protein Expression Market:
• Agilent Technologies
• Ajinomoto Bio-Pharma Services
• Aldevron
• ARTES Biotechnology GmbH
• Bio-Rad Laboratories
• BIONEER CORPORATION
• Cayman Chemical
• Charles River Laboratories
• CORNING INCORPORATED
• Domainex
• DANAHER CORPORATION
• Eurofins CALIXAR
• FUJIFILM IRVINE SCIENTIFIC, INC.
• GeNext Genomics
• GenScript Biotech
• Lonza
• Lucigen Corporation
• LifeSensors Inc
• LEADING BIOLOGY, INC.
• Merck KGaA
• New England Biolabs
• Oxford Expression Technologies
• ProMab
• Promega
• ProteoGenix
• Peak Proteins Ltd
• QIAGEN
• Sartorius
• Synbio Technologies
• Syngene
• Synthetic Genomics Inc
• Sino Biological Inc
• JENA BIOSCIENCE
• Takara Bio
• Thermo Fisher Scientific
• WuXi Biologics

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Market Dynamics:
Drivers:
The increasing use of biologics (therapeutic proteins, monoclonal antibodies, and vaccines) for treating diseases like cancer, autoimmune disorders, and chronic conditions is a major driver. Biologics are more complex than traditional small-molecule drugs, requiring efficient protein expression systems for their development. The rapid expansion of the biotechnology and pharmaceutical sectors is driving demand for advanced protein expression technologies. This growth is linked to new drug discovery, personalized medicine, and therapeutic proteins. Innovations in expression systems, including mammalian, yeast, plant-based, insect, and cell-free systems, are improving the efficiency, scalability, and sustainability of protein production, fueling market growth.

Challenges:
Producing complex proteins, especially those that require post-translational modifications like glycosylation, can be challenging. Prokaryotic systems like E. coli are often unable to produce properly folded or modified proteins, necessitating more complex and costly systems like mammalian cells.

Regional Trends:
North America, particularly the U.S., holds the largest market share due to its well-established biotechnology and pharmaceutical industries, extensive research and development (R&D) activities, and high healthcare expenditure. The growing prevalence of chronic diseases, including cancer and autoimmune disorders, creates significant demand for therapeutic proteins like monoclonal antibodies and vaccines. However, The Asia-Pacific region is experiencing the fastest growth in the protein expression market, driven by increasing investment in biotechnology, growing pharmaceutical industries, and rising healthcare needs. Asia-Pacific is a hub for outsourcing protein expression and biopharmaceutical production due to lower costs and the availability of skilled labor. Many global companies outsource production to countries in this region.

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Recent Developments:
• In June 2024, HERCULES, Calif.,Bio-Rad Laboratories, Inc. The launch of the ddSEQTM Single-Cell 3' RNA-Seq Kit and corresponding Omnition v1.1 analysis software for single-cell transcriptome and gene expression research was announced by a global leader in life science research and clinical diagnostics products.
• In April 2023, Eurofins CALIXAR, declared the purchase of CALIXAR, a pioneer in providing the best membrane proteins for the life sciences. The purchase strengthens Eurofins Discovery and Eurofins DiscoverX®'s scientific leadership in G Protein-Coupled Receptors (GPCRs) and ion channels and provides critical capabilities in membrane protein synthesis of highly druggable targets. Gaining more knowledge in these crucial fields enhances the business's Biophysics and Biotherapeutics platforms, as well as its Integrated Drug Discovery platform, DiscoveryOneTM.
• In March 20022, ProteoGenix, declares the release of its transient expression system, XtenCHOTM. In comparison to previous methods, the novel patented mammalian cell-based expression host produces up to ten times higher yields with less hands-on time because of its optimised metabolism and enhanced plasmid stability. The novel CHO host seeks to expedite early phase drug screening and streamline the manufacture of recombinant proteins.

Segmentation of Protein Expression Market.
Global Protein Expression Market- By Type of Protein Expression System
• Algal Expression Systems
• Cell-free Expression Systems
• Insect Expression Systems
• Mammalian Expression Systems
• Prokaryotic Expression Systems
• Yeast Expression Systems
Global Protein Expression Market - Protein Expression-related Offerings
• Competent Cells
• Expression Vectors
• Instruments
• Kits and Reagents
• Protein Expression Services
Global Protein Expression Market - By Application
• Research and Diagnostics
• Therapeutics
Global Protein Expression Market - By End user
• Academic and Research Institutes
• CROs and CDMOs
• Pharmaceutical and Biotechnology Companies
• Other End-users
• Type of Operation
• In-house Operations
• Outsourced Operations
Global Protein Expression Market - Type of Operation
• In-house Operations
• Outsourced Operations
Global Protein Expression Market - By Region
North America-
• The US
• Canada
• Mexico
Europe-
• Germany
• The UK
• France
• Italy
• Spain
• Rest of Europe
Asia-Pacific-
• China
• Japan
• India
• South Korea
• Southeast Asia
• Rest of Asia Pacific
Latin America-
• Brazil
• Argentina
• Rest of Latin America
Middle East & Africa-
• GCC Countries
• South Africa
• Rest of the Middle East and Africa

About Us:
InsightAce Analytic is a market research and consulting firm that enables clients to make strategic decisions. Our qualitative and quantitative market intelligence solutions inform the need for market and competitive intelligence to expand businesses. We help clients gain competitive advantage by identifying untapped markets, exploring new and competing technologies, segmenting potential markets and repositioning products. Our expertise is in providing syndicated and custom market intelligence reports with an in-depth analysis with key market insights in a timely and cost-effective manner.

Contact us:
InsightAce Analytic Pvt. Ltd.
Visit: www.insightaceanalytic.com
Tel : +1 551 226 6109
Asia: +91 79 72967118
info@insightaceanalytic.com

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