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Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Pipeline Analysis, Clinical Trials, EMA, PDMA, FDA Approvals, Medication, Treatment Market, Therapies, MOA, ROA, Companies by DelveInsight

01-15-2025 07:03 AM CET | Health & Medicine

Press release from: DelveInsight Business Research

Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Pipeline

Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Pipeline

(Albany, USA) "Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Pipeline Insight 2024" report by DelveInsight provides a comprehensive analysis of the ongoing clinical development activities and growth prospects across the Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Therapeutics Market.

Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Pipeline constitutes 180+ key companies continuously working towards developing 200+ Chimeric Antigen Receptor T-Cell Therapy (CAR-T) treatment therapies, analyzes DelveInsight.

Download a sample report @ https://www.delveinsight.com/report-store/chimeric-antigen-receptor-t-cell-therapy-car-t-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr

Key Takeaways from the Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Pipeline Report:
• DelveInsight's Chimeric Antigen Receptor T-Cell Therapy (CAR-T) pipeline report depicts a robust space with 180+ active players working to develop 220+ pipeline therapies for Chimeric Antigen Receptor T-Cell Therapy (CAR-T) treatment.
• On November 8, 2024, Autolus Therapeutics (Nasdaq: AUTL) announced that the U.S. FDA granted approval for AUCATZYL® (obecabtagene autoleucel) to treat adult patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (r/r B-ALL).
• In March 2024, Bristol Myers Squibb announced that the U.S. FDA approved BREYANZI as the first CAR T-cell therapy specifically for adults with relapsed or refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).
• In May 2024, Verismo Therapeutics received FDA clearance for an investigational new drug (IND) application for SynKIR-310 to treat relapsed or refractory B-cell non-Hodgkin lymphoma (NHL).
• Key Chimeric Antigen Receptor T-Cell Therapy (CAR-T) companies such as Cartesian Therapeutics, Arcellx, Inc, Nexcella, Inc, Autolus Therapeutics, Sana Biotechnology, and others are evaluating new drugs for Chimeric Antigen Receptor T-Cell Therapy (CAR-T) to improve the treatment landscape.
• Promising Chimeric Antigen Receptor T-Cell Therapy (CAR-T) pipeline therapies in various stages of development include Descartes-08, CART-ddBCMA, NXC-201, AUTO-8, SG299, and others.

Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Overview:

CAR T-cells are engineered fusion proteins combining a single-chain fragment variable (scFv) from a specific monoclonal antibody with one or more intracellular signaling domains of T-cell receptors (TCR). These chimeric antigen receptors (CARs) merge antigen-binding domains-typically derived from the variable regions of antibodies-with TCR signaling domains and additional co-stimulatory domains, such as CD28, OX40, or CD137. CAR T-cells not only have the potential to eliminate all cancer cells but may also persist in the body for months post-infusion.

T-cells, a type of white blood cell, play a crucial role in identifying and combating illness and infections by recognizing antigens-proteins or molecules that trigger immune responses. When foreign or abnormal antigens are detected, the immune system targets and destroys them. Since their initial development in 1989, CAR T-cells have evolved into four generations, distinguished by their intracellular domain structures.

Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Pipeline Analysis
The report provides insights into:
• The report provides detailed insights into the key companies that are developing therapies in the Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Market.
• The report also evaluates different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Chimeric Antigen Receptor T-Cell Therapy (CAR-T) treatment.
• It analyzes the key companies involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
• It navigates the emerging drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement, and financing details for future advancement of the Chimeric Antigen Receptor T-Cell Therapy (CAR-T) market.

Request for a sample report @ https://www.delveinsight.com/report-store/chimeric-antigen-receptor-t-cell-therapy-car-t-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr

Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Companies
There are approx. 180+ key companies which are developing the therapies for Chimeric Antigen Receptor T-Cell Therapy (CAR-T). The companies which have their Chimeric Antigen Receptor T-Cell Therapy (CAR-T) drug candidates in the most advanced stage, i.e. phase II include, Cartesian Therapeutics.

DelveInsight's report covers around 200+ products under different phases of clinical development like
• Late stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I) along with the details of
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates

Chimeric Antigen Receptor T-Cell Therapy (CAR-T) pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
• Oral
• Intravenous
• Subcutaneous
• Parenteral
• Topical

CAR-T Products have been categorized under various Molecule types such as
• Recombinant fusion proteins
• Small molecule
• Monoclonal antibody
• Peptide
• Polymer
• Gene therapy

Download Sample Pages to Get an in-depth Assessment of the Emerging Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Therapies and Key Companies: Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Clinical Trials and advancements - https://www.delveinsight.com/sample-request/chimeric-antigen-receptor-t-cell-therapy-car-t-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr

Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Pipeline Therapeutic Assessment
• Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Assessment by Product Type
• Chimeric Antigen Receptor T-Cell Therapy (CAR-T) By Stage
• Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Assessment by Route of Administration
• Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Assessment by Molecule Type

Download Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Sample report to know in detail about the Chimeric Antigen Receptor T-Cell Therapy (CAR-T) treatment market @ Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Therapeutic Assessment
https://www.delveinsight.com/report-store/chimeric-antigen-receptor-t-cell-therapy-car-t-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr

Table of Content
1. Report Introduction
2. Executive Summary
3. Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Current Treatment Patterns
4. Chimeric Antigen Receptor T-Cell Therapy (CAR-T) - DelveInsight's Analytical Perspective
5. Therapeutic Assessment
6. Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Late-Stage Products (Phase-III)
7. Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Mid-Stage Products (Phase-II)
8. Early Stage Products (Phase-I)
9. Pre-clinical Products and Discovery Stage Products
10. Inactive Products
11. Dormant Products
12. Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Discontinued Products
13. Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Product Profiles
14. Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Key Companies
15. Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Key Products
16. Dormant and Discontinued Products
17. Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Unmet Needs
18. Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Future Perspectives
19. Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Analyst Review
20. Appendix
21. Report Methodology

Request the Sample PDF to Get Detailed Insights About the Chimeric Antigen Receptor T-Cell Therapy (CAR-T) Pipeline Reports Offerings: https://www.delveinsight.com/report-store/chimeric-antigen-receptor-t-cell-therapy-car-t-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr

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Ankit Nigam
Manager Marketing
info@delveinsight.com
+14699457679
https://www.delveinsight.com/
Case Study: https://www.delveinsight.com/case-study/conference-intelligence-product-assessment

About DelveInsight
DelveInsight is a leading Life Science market research and business consulting company recognized for its off-the-shelf syndicated market research reports and customized solutions to firms in the healthcare sector.

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